Solid-State NMR Studies of Bone

  • Waclaw KolodziejskiEmail author
Part of the Topics in Current Chemistry book series (TOPCURRCHEM, volume 246)


Solid-state NMR studies on bone, bone mineral standards and collagen are reviewed. NMR spectroscopy was mostly applied to the bone mineral and confirmed that the structure resembles that of calcium carbonatoapatite of type B. Apatite in bone was found to be deficient in structural hydroxyl groups. Concentration and distribution of hydrogenphosphate and carbonate ions, and of water in apatite crystals (interior vs surface and crystal defects vs structural positions) were closely investigated. The NMR characterization of the organic matrix still remains a challenge for future research.

Bone Apatite Structure Solid-state NMR Cross-polarization 


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Copyright information

© Springer-Verlag Berlin Heidelberg 2005

Authors and Affiliations

  1. 1.Faculty of Pharmacy, Department of Inorganic and Analytical ChemistryMedical University of WarsawWarszawaPoland

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