Synthetic Studies on the Pamamycin Macrodiolides

  • Peter MetzEmail author
Part of the Topics in Current Chemistry book series (TOPCURRCHEM, volume 244)


The pamamycins are structurally intriguing 16-membered macrodiolides displaying a wide range of interesting biological activities. A comprehensive survey of the total syntheses reported in this area so far and the various synthetic approaches to the hydroxy acid constituents of the pamamycins described to date is presented.

Pamamycins Macrodiolides Antibiotics Synthesis Hydroxy acids 


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Authors and Affiliations

  1. 1.Institut für Organische ChemieTechnische Universität DresdenDresdenGermany

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