Abstract
Radiation therapy is an important modality in the management of pelvic malignancies. Of cancer diagnosed in the year 2005, approximately 45% of male patients (prostate, rectal, bladder) and 25% of female patients (uterine, rectal, cervical, and bladder) had pelvic malignancies. More than half of all patients diagnosed with cancer receive radiation as part of their treatment.
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Hall E. Radiobiology for the Radiologist. Philadelphia: Lippincott Williams & Wilkins; 2000:5–91.
Halperin EC, Schmidt-Ullrich, Perez C, Brady L. The discipline of radiation oncology. In: Perez C, Halperin E, Brady L, Schmidt-Ullrich R, eds. Principles and Practice of Radiation Oncology. Philadelphia: Lippincott Williams & Wilkins; 2004:17.
Alektiar K, Zelefsky M. Instruments and techniques in brachytherapy. In: Leibel S, Phillips T, eds. Textbook of Radiation Oncology. New York: Elsevier; 2004:265–90.
Dearlnaley D, Khoo V, Norman A, Meyer L, Nahum A, Tait D, Yarnold J, Horwich A. Comparison of radiation side effects of conformal and conventional radiotherapy in prostate cancer: a randomized trial. Lancet. 1999;353:267–72.
Dong L, Mohan R. Intensity modulated radiation therapy physics and quality assurance. In: Chao C, ed. Practical Essentials of Intensity Modulated Radiation Therapy. Philadelphia: Lippincott Williams & Wilkins; 2005:1–18.
Pirzkall A, Carol M, Lohr F, Hoss A, Wannenmacher M, Debus J. Comparison of intensity-modulated radiotherapy with conventional conformal radiotherapy for complex-shaped tumors. Int J Radiat Oncol Biol Phys. 2000;48:1371–80.
Eifel P, Morris M, Wharton J, Oswald M. The influence of tumor size and morphology on the outcome of patients with FIGO stage IB squamous cell carcinoma of the uterine cervix. Int J Radiat Oncol Biol Phys. 1994;29:9–16.
Gelfand MD, Tepper M, Katz LA, Binder HJ, Yesner R, Floch MH. Acute irradiation proctitis in man: development of eosinophilic crypt abscesses. Gastroenterology. 1968;54:401–11.
Weisbrot IM, Liber AF, Gordon BS. The effects of therapeutic radiation on colon mucosa. Cancer. 1975;36:931–40.
Keys H, Bundy B, Stehman F, Muderspach L, Chafe W, Suggs C, Walker J, Gersell D. Cisplatin, radiation, and adjuvant hysterectomy compared with radiation and adjuvant hysterectomy for bulky stage IB cervical carcinoma. N Engl J Med. 1999;340:1154–61.
Milliat F, Francois A, Isoir M, Deutsch E, Tamarat R, Tarlet G, Atfi A, Validire P, Bourhis J, Sabourin J, Benderitter M. Influence of endothelial cells on vascular smooth muscle cells phenotype after irradiation. Am J Pathol. 2006;169:1484–95.
Anscher MS, Vujaskovic Z. Mechanisms and potential targets for prevention and treatment of normal tissue injury after radiation therapy. Semin Oncol. 2005 Apr;32(Suppl 3):S86–91.
Skwarchuk M, Jackson A, Zelefsky M, Venkatramna E, Cowen D, Levegrun S, Ling C. Late rectal toxicity after conformal radiotherapy of prostate cancer: multivariate analysis and dose response. Int J Radiat Oncol Biol Phys. 2000;47:103–13.
Hall E. A compilation of tissue and organ sensitivities. In: Hall E, ed. Radiobiology for the Radiologist. Philadelphia: Lippincott Williams & Wilkins; 2000:350.
Eifel PJ, Levenback, C, Wharton T, Oswald MJ. Time course and incidence of late complications in patients treated with radiation therapy for FIGO stage IB carcinoma of the uterine cervix. Int J Radiat Oncol Biol Phys. 1995;32:1289–300.
Wang C, Leung W, Chen C. The correlation of acute toxicity and late rectal injury in radiotherapy for cervical carcinoma: evidence suggestive of consequential late effect. Int J Radiat Oncol Biol Phys. 1998;40:85–91.
Reis ED, Vine AJ, Heimann T. Radiation damage to the rectum and anus: pathophysiology, clinical features and surgical implications. Colorectal Dis. 2001;4:2–12.
Antonakopoulos GN, Hicks RM, Berry RJ. The subcellular basis of damage to the human urinary bladder induced by irradiation. J Pathol. 1984;143:103–16.
Petrovich Z, Stein J, Jozsef G, Formenti S. Bladder—treatment toxicity and its impact on quality of life. In: Perez C, Halperin E, Brady L, Schmidt-Ullrich R, eds. Principles and Practice of Radiation Oncology. Philadelphia: Lippincott Williams & Wilkins; 2004:1685–6.
Gellrich, J, Hakenberg OW, Oehlschlager S, Wirth MP. Manifestation, latency, and management of late urological complications after curative radiotherapy for cervical carcinoma. Onkologie. 2003;26:334–40.
Stephenson AJ, Scardino PT, Bianco FJ Jr, DiBlasio CJ, Fearn PA, Eastham JA. Morbidity and functional outcomes of salvage radical prostatectomy for locally recurrent prostate cancer after radiation therapy. J Urol. 2004 Dec;172(6 Pt 1):2239–43.
Ward JF, Sebo TJ, Blute ML, Zincke H. Salvage surgery for radiorecurrent prostate cancer: contemporary outcomes. J Urol. 2005 Apr;173(4):1156–60.
Sanderson KM, Penson DF, Cai J, Groshen S, Stein JP, Lieskovsky G, Skinner DG. Salvage radical prostatectomy: quality of life outcomes and long-term oncological control of radiorecurrent prostate cancer. J Urol. 2006 Nov;176(5):2025–31; discussion 2031–2.
Vallancien G, Gupta R, Cathelineau X, Baumert H, Rozet F. Initial results of salvage laparoscopic radical prostatectomy after radiation failure. J Urol. 2003 Nov;170(5):1838–40.
Touma NJ, Izawa JI, Chin JL. Current status of local salvage therapies following radiation failure for prostate cancer. J Urol. 2005 Feb;173(2):373–9. Review.
Kim HL, Steinberg GD. The current status of bladder preservation in the treatment of muscle invasive bladder cancer. J Urol. 2000 Sep;164(3 Pt 1):627–32. Review.
Nieuwenhuijzen JA, Horenblas S, Meinhardt W, van Tinteren HV, Moonen LM. Salvage cystectomy after failure of interstitial radiotherapy and external beam radiotherapy for bladder cancer. BJU Int. 2004 Oct;94(6):793–7.
Bochner BH, Figueroa AJ, Skinner EC, Lieskovsky G, Petrovich Z, Boyd SD, Skinner DG. Salvage radical crystoprostatectomy and orthotopic uninary diversion following radiation failure. J Urol. 1998;160(1):29–33.
Wammack R, Wricke C, Hohenfellner R. Long-term results of ileocecal continent urinary diversion in patients treated with and without previous pelvic irradiation. J Urol. 2002 May;167(5):2058–62.
Evangelidis A, Lee EK, Karellas ME, Thrasher JB, Holzbeierlein JM. Evaluation of ureterointestinal anastomosis: Wallace vs Bricker. J Urol. 2006 May;175(5):1755–8; discussion 1758.
Chang SS, Alberts GL, Smith JA, Cookson MS. Ileal conduit urinary diversion in patients with previous history of abdominal/pelvic irradiation. World J Urol. 2004 Oct;22(4):272–6. Epub 2004 Sep 21.
Wilkin M, Horwitz G, Seetharam A, Hartenback E, Schink JC, Bruskewitz R, Jarrard DF. Long-term complications associated with the Indiana pouch urinary diversion in patients with recurrent gynecologic cancers after high-dose radiation. Urol Oncol. 2005 Jan–Feb;23(1):12–15.
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Lee, E.K., Klish, D., Holzbeierlein, J. (2009). Complications of Surgery After Pelvic Radiation. In: Billingham, R., Kobashi, K., Peters, W. (eds) Reoperative Pelvic Surgery. Springer, New York, NY. https://doi.org/10.1007/b14187_21
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DOI: https://doi.org/10.1007/b14187_21
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