Abstract
Interface tissue engineering is an exciting field which focuses on the development of tissue engineered grafts capable of promoting integration between different types of tissue and between the implant and surrounding tissue. Focusing on interface tissue engineering, and using the insertion site between the anterior cruciate ligament and bone as an example, this chapter discusses strategies in soft tissue to bone integration as well as current tissue engineering efforts in this area. This review begins with the clinical significance of this problem, followed by a review of existing fixation methods, and tissue engineering efforts aimed at addressing this critical issue. The development of multi-phased scaffolds designed for the replacement of more than one type of tissue, as well as novel in vitro co-culture systems will be introduced. Future directions in the field of interface tissue engineering will also be discussed.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
Abbreviations
- 3-D:
-
Three-dimensional
- ACL:
-
Anterior crucial ligament
- BG:
-
45S5 bioactive glass
- hBMSCs:
-
Human bone marrow stromal cells
- GAG:
-
Glycosaminoglycan
- PLAGA:
-
Poly(lactide-co-glycolide)
- SEM:
-
Scanning electron microscopy
References
Johnson RJ (1982) Int J Sports Med 3:71–79
American Academy of Orthopaedic Surgeons (1997) Arthoplasty and Total Joint Replacement Procedures: United States 1990–1997, United States
Noyes FR, Mangine RE, Barber S (1987) Am J Sports Med 15:149–160
Daniel DM et al. (1994) Am J Sports Med 22:632–644
Thomas NP, Turner IG, Jones CB (1987) J Bone Joint Surg Br 69:312–316
Fujikawa K, Iseki F, Seedhom BB (1989) J Bone Joint Surg Br 71:566–570
Bolton CW, Bruchman WC (1985) Clin Orthop 202–213
McCarthy DM, Tolin BS, Schwendeman L, Friedman MJ, Woo SL (1993) The Anterior Cruciate Ligament: Current and Future Concepts, Douglas W and Jackson MD (eds.) Raven, New York
McPherson GK et al. (1985) Clin Orthop 186–195
Yahia L (1997) Ligaments and Ligamentoplasties. Springer Verlag, Berlin Heidelberg New York
Friedman MJ et al. (1985) Clin Orthop 9–14
Larson RP (1994) The Crucial Ligaments: Diagnosis and Treatment of Ligamentous Injuries About the Knee, John A, Feagin JA (eds.) Churchill Livingstone, New York
Jackson DW (1992) Am Acad Orthop Surg Bull 40:10–11
Jackson DW, Grood ES, Arnoczky SP, Butler DL, Simon TM (1987) Am J Sports Med 15:528–538
Jackson DW, Grood ES, Goldstein JD, Rosen MA, Kurzweil PR, Simon TM (1991) Trans Orhtop Res Soc 16:208
Jackson DW et al. (1993) Am J Sports Med 21:176–185
Fleming BC, Abate JA, Peura GD, Beynnon BD (2001) J Orthop Res 19:841–844
Fleming BC, Beynnon B, Howe J, McLeod W, Pope M (1992) J Orthop Res 10:177–186
Beynnon BD et al. (1996) J Biomech Eng 118:227–239
Beynnon BD et al. (1997) Am J Sports Med 25:353–359
Loh JC et al. (2003) Arthroscopy 19:297–304
Markolf KL et al. (2002) J Orthop Res 20:1016–1024
Kurosaka M, Yoshiya S, Andrish JT (1987) Am J Sports Med 15:225–229
Robertson DB, Daniel DM, Biden E (1986) Am J Sports Med 14:398–403
Noyes FR, Barber-Westin SD (1996) Clin Orthop 116–129
Brand J, Weiler A, Caborn DN, Brown CH, Johnson DL (2000) Am J Sports Med 28:761–774
Steiner ME, Hecker AT, Brown CH, Hayes WC (1994) Am J Sports Med 22:240–246
Berg EE (1996) Arthroscopy 12:232–235
Matthews LS, Soffer SR (1989) Arthroscopy 5:225–226
Kurzweil PG, Frogameni AD, Jackson DW (1995) Arthroscopy 11:289–291
Burkart A, Imhoff AB, Roscher E (2000) Arthroscopy 16:91–95
Shellock FG, Mink JH, Curtin S, Friedman MJ (1992) J Magn Reson Imaging 2:225–228
Safran MR, Harner CD (1996) Clin Orthop 50–64
Allum RL (2001) Knee 8:69–72
Weiler A, Hoffmann RF, Bail HJ, Rehm O, Sudkamp NP (2002) Arthroscopy 18:124–135
Abate JA, Fadale PD, Hulstyn MJ, Walsh WR (1998) Arthroscopy 14:278–284
Pena P, Grontvedt T, Brown GA, Aune AK, Engebretsen L (1996) Am J Sports Med 24:329–334
Weiler A, Windhagen HJ, Raschke MJ, Laumeyer A, Hoffmann RF (1998) Am J Sports Med 26:119–126
Weiler A, Helling HJ, Kirch U, Zirbes TK, Rehm KE (1996) J Bone Joint Surg Br 78:369–376
Panni AS, Milano G, Lucania L, Fabbriciani C (1997) Clin Orthop 203–212
Thomopoulos S et al. (2002) J Orthop Res 20:454–463
Rodeo SA, Arnoczky SP, Torzilli PA, Hidaka C, Warren RF (1993) J Bone Joint Surg Am 75:1795–1803
Liu SH et al. (1997) Clin Orthop Related Res 253–260
Yoshiya S, Nagano M, Kurosaka M, Muratsu H, Mizuno K (2000) Clin Orthop 278–286
Anderson K et al. (2001) Am J Sports Med 29:689–698
Chen CH et al. (2003) Arthroscopy 19:290–296
Grana WA, Egle DM, Mahnken R, Goodhart CW (1994) Am J Sports Med 22:344–351
Blickenstaff KR, Grana WA, Egle D (1997) Am J Sports Med 25:554–559
Fu FH, Bennett CH, Ma CB, Menetrey J, Lattermann C (2000) Am J Sports Med 28:124–130
Rodeo SA, Suzuki K, Deng XH, Wozney J, Warren RF (1999) Am J Sports Med 27:476–488
Butler DL, Goldstein SA, Guilak F (2000) J Biomech Eng 122:570–575
Harner CD et al. (1999) Arthroscopy 15:741–749
Messner K (1997) Acta Anatomica 160:261–268
Gao J, Messner K (1996) J Anat 188:367–373
Niyibizi C, Sagarrigo VC, Gibson G, Kavalkovich K (1996) Biochem Biophys Res Commun 222:584–589
Petersen W, Tillmann B (1999) Anat Embryol (Berl) 200:325–334
Sagarriga VC, Kavalkovich K, Wu J, Niyibizi C (1996) Arch Biochem Biophys 328:135–142
Wei X, Messner K (1996) Anat Embryol (Berl) 193:53–59
Cooper RR, Misol S (1970) J Bone Joint Surg Am 52:1–20
Clark JM, Sidles JA (1990) J Orthop Res 8:180–188
Mommersteeg TJ et al. (1994) J Orthop Res 12:238–245
Woo SL, Gomez MA, Seguchi Y, Endo CM, Akeson WH (1983) J Orthop Res 1:22–29
Butler DL et al. (1992) J Biomech 25:511–518
Gao J, Rasanen T, Persliden J, Messner K (1996) J Anat 189:127–133
Matyas JR, Anton MG, Shrive NG, Frank CB (1995) J Biomech 28:147–157
Woo SL, Newton PO, MacKenna DA, Lyon RM (1992) J Biomech 25:377–386
Benjamin M, Evans EJ, Rao RD, Findlay JA, Pemberton DJ (1991) J Anat 177:127–134
Scapinelli R, Little K (1970) J Pathol 101:85–91
Brody GA, Eisinger M, Arnoczky SP, Warren RF (1988) Am J Sports Med 16:203–208
Dunn MG, Liesch JB, Tiku ML, Maxian SH, Zawadsky JP (1994) Mater Res Soc 331:13–18
Bellincampi LD, Closkey RF, Prasad R, Zawadsky JP, Dunn MG (1998) J Orthop Res 16:414–420
Altman GH et al. (2002) Biomaterials 23:4131–4141
Altman GH et al. (2002) J Biomech Eng 124:742–749
Goulet F et al. (2000) Principles of Tissue Engineering, Lanza RP, Langer R, Vacanti JP, (eds.) Academic, New York
Cooper JA, Lu HH, Ko FK, Freeman JW, Laurencin CT (2005) Biomaterials 26:1523–1532
Lu HH, Cooper JA Jr, Manuel S, Freeman JW, Attawia MA, Ko FK, Laurencin CT (2005) Biomaterials 26:4805–4816
Cooper JA (2002) thesis, Drexel University
Lu HH, El Amin SF, Scott KD, Laurencin CT (2003) J Biomed Mater Res 64A:465–474
Jiang J, Nicoll SB, Lu HH (2003) Effects of Osteoblast and Chondrocyte Co-Culture on Chondrogenic and Osteoblastic Phenotype In Vitro. Trans Orth Res Soc 49
Lu HH, Jeffries DT, Choi RY, Oh S, Ahmad C, Policarpio EL (2003) Evaluation of Optimal Parameters in the Co-culture of Human Anterior Cruciate Ligament Fibroblasts and Osteoblasts for Interface Tissue Engineering. ASME 2003 Summer Bioengineering Conference
Wang IE, Jeffries DT, Jiang J, Chen FH, Lu HH (2004) Effects of co-culture on ligament fibroblast and osteoblast growth and differentiation. Transactions of the 50th Annual Meeting of the Orthopaedic Research Society
Spalazzi JP, Dionisio KL, Jiang J, Lu HH (2003) IEEE Eng Med Biol Mag 22:27–34
Amis AA, Kempson SA, Campbell JR, Miller JH (1988) J Bone Joint Surg Br 70:628–634
Dunn MG et al. (1992) Am J Sports Med 20:507–515
Bolton W, Bruchman B (1983) Aktuelle Probl Chir Orthop 26:40–51
Arnoczky SP, Torzilli PA, Warren RF, Allen AA (1988) Am J Sports Med 16:106–112
Amis AA, Camburn M, Kempson SA, Radford WJ, Stead AC (1992) J Bone Joint Surg Br 74:605–613
Paavolainen P, Mäkisalo S, Skutnabb K, Holmström T (1993) Acta Orthop Scand 64:323–328
Weiler A, Hoffmann RF, Bail HJ, Rehm O, Sudkamp NP (2002) Arthroscopy 18:124–135
Acknowledgments
The authors would like to acknowledge funding support from the Whitaker Foundation and the National Institutes of Health.
Author information
Authors and Affiliations
Corresponding author
Editor information
Rights and permissions
Copyright information
© 2005 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Lu, H.H., Jiang, J. (2005). Interface Tissue Engineeringand the Formulation of Multiple-Tissue Systems. In: Lee, K., Kaplan, D. (eds) Tissue Engineering I. Advances in Biochemical Engineering/Biotechnology, vol 102. Springer, Berlin, Heidelberg . https://doi.org/10.1007/b138509
Download citation
DOI: https://doi.org/10.1007/b138509
Published:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-31944-3
Online ISBN: 978-3-540-31948-1
eBook Packages: Chemistry and Materials ScienceChemistry and Material Science (R0)