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Action of polyvinyl pyrrolidone on the interaction of polysilicic acid with human serum albumin monolayers

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Polymere Aspekte

Part of the book series: Progress in Colloid & Polymer Science ((PROGCOLLOID,volume 58))

Abstract

The interaction between polysilicic acid and human serum albumin monolayers can be inhibited by the action of polyvinyl pyrrolidone (PVP). This effect is produced by a competition between the polymer and the protein for the silanol groups of polysilicic acid. The results obtained show that in a substrate containing 0.30 g/l of SiO2 in form of polysilicic acid a concentration of 80 mg/l of PVP is enough to produce the inhibition of the silicic-protein interaction.

The inhibition caused by a certain quantity of PVP depends on the polymerization time of silicic acid and on the time elapsed from the moment in which the acid is added to the substrate until the record of the isotherms starts.

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Author notes

  1. S. García Fernández

    Present address: Department of Physical Chemistry. Faculty of Pharmacy, University of Barcelona, Spain

Authors and Affiliations

  1. Department of Physical Chemistry, Faculty of Pharmacy, University of Santigo de Compostela, Spain

    J. Miñones, E. Iribarnegaray, S. García Fernández & P. Sanz Pedrero

Authors
  1. J. Miñones
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  2. E. Iribarnegaray
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  3. S. García Fernández
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  4. P. Sanz Pedrero
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© 1975 Dr. Dietrich Steinkopff Verlag GmbH & Co. KG

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Miñones, J., Iribarnegaray, E., Fernández, S.G., Pedrero, P.S. (1975). Action of polyvinyl pyrrolidone on the interaction of polysilicic acid with human serum albumin monolayers. In: Polymere Aspekte. Progress in Colloid & Polymer Science, vol 58. Steinkopff. https://doi.org/10.1007/BFb0117139

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  • DOI: https://doi.org/10.1007/BFb0117139

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  • Publisher Name: Steinkopff

  • Print ISBN: 978-3-7985-1796-7

  • Online ISBN: 978-3-7985-1797-4

  • eBook Packages: Springer Book Archive

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