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Ahlquist, R. P.: A study of the adrenotropic receptors. Amer. J. Physiol. 153, 586–600 (1948).
Annersten, Sv., A. Grönwall and E. Köiw: Determination of adrenaline in blood plasma by the fluorescence method. Nature (Lond.) 163, 136–137 (1949).
Åström, A.: Anti-sympathetic action of sympathomimetic amines. Acta physiol. scand. (Stockh.) 18, 295–307 (1949).
Auerbach, M. E., and E. Angell: The determination of arterenol in epinephrine. Science (Lancaster, Pa,) 109, 537–538 (1949).
Babsky, E. B.: Sur la formation de substance physiologiquement actives dans les fibres nerveux. Bull. biol. med. Exper. URSS. 5, 51–54 (1938).
Bacq, Z. M.: Recherches sur la physiologie du système nerveux autonome. III. Les proprietés biologiques et physico-chimiques de la sympathine comparées à celles de l'adrénaline. Arch. internat. Physiol. 36, 167–246 (1933).
—La pharmacologie du système nerveux autonome, et particulièrement du sympatique, d'après la théorie neurohumorale. Ann. de Physiol. 10, 467–553 (1934).
—Artérénol ou adrénaline dans les extraits de tissus. C. r. Soc. Biol. Paris 141, 963–964 (1947).
—Métabolisme et synthése de l'adrénaline. Bull. Acad. Suisse Sci. Med. 4, 127–140 (1948a).
—Facts and theories about sympathins. Science (Lancaster, Pa.) 108, 135 (1948b).
— and P. Fischer: Nature de la substance sympathicomimétique extraite des nerfs ou des tissus des mammifères. Arch. internat. Physiol. 55, 73 (1947).
—, and H. Frédéricq: Sur la nature de l'innervation de la rate. Actions de divers agents pharmacodynamiques. Arch. internat. Physiol. 41, 322–333 (1935).
Barcroft, H., and H. Konzett: action of noradrenaline and adrenaline on human heart-rate. Lancet 1949, 147–148.
Barger, G.: Georg Fisher Baker Lecture 5. New York: McGrow Hill, Co. 1930.
—, and H. H. Dale: Chemical structure and sympathomimetic action of amines. J. of Physiol. 41, 19–59 (1910–1911).
Bergström, S., and Hansson: To be published 1950.
—, U. S. v. Euler and U. Hamberg: Isolation of nor-adrenaline from the adrenal gland. acta chem. scand. (Stockh.) 3, 305 (1949).
— Isolation of noradrenaline from suprarenal medulla. Acta physiol. scand. (Stockh.) 20, 101–108 (1950).
Beyer, K. H., and S. H. Shapiro: The excretion of conjugated epinephrine related compounds. Amer. J. Physiol. 144, 321–330 (1945).
Biberfeld, J.: Pharmakologische Eigenschaften eines synthetisch dargestellten Suprarenins und einiger seiner Derivate. Med. Klin. 1906, 1177–1179.
Blaschko, H.: The activity of l(−)-dopa decarboxylase. J. of Physiol. 101, 337 bis 349 (1942).
—Substrate specificity of amino-acid decarboxylases. Biochim. et Biophys. Acta 4, 130–137 (1950).
—, P. Holton and G. H. S. Stanley: The decarboxylation of β 3∶4-dihydroxyphenylserine (Noradrenaline carboxylic acid). Brit. J. Pharmacol. 3, 315–319 (1948).
—, D. Richter and H. Schlossmann: Oxidation of adrenaline and other amines. Biochemic. J. 31, 2187–2196 (1937).
Bloor, W. R., and S. S. Bullen: The determination of adrenaline in blood. J. of biol. Chem. 138, 727–739 (1941).
Bülbring, E.: The methylation of noradrenaline by minced suprarenal tissue. Brit. J. Pharmacol 4, 234–244 (1949).
—, and J. H. Burn: Liberation of noradrenaline from the suprarenal gland. Brit. J. Pharmacol. 4, 202–208 (1949).
Burn, J. H., and D. E. Hutcheon: The action of noradrenaline. Brit. J. Pharmacol. 4, 373–380 (1949).
Calabro, Q.: Riv. Biol. 15, 299 (1933).
Cannon, W. B., and Z. M. Bacq: Studies on the conditions of activity in endocrine organs. XXVI. A hormone produced by sympathetic action on smooth muscle. Amer. J. Physiol. 96, 392–412 (1931).
—, and K. Lissák: Evidence for adrenaline in adrenergic neurones. Amer. J. Physiol. 125, 765–777 (1939).
—, and A. Rosenblueth: Sympathin E and sympathin I. Amer. J. Physiol. 104, 557–574 (1933).
— Autonomic neuro-effector systems. New York: MacMillan 1937.
—, and J. E. Uridil: Studies on the conditions of activity in endocrine glands. VIII. Some effects on the denervated heart of stimulating the nerves of the liver. Amer. J. Physiol. 58, 353 (1921).
Cerletti, A., and A. Kallenberger: Über die Beeinflussung der Hypoxieprobe am Menschen durch pharmakodynamische Sympathicolyse. Helvet. physiol. Acta 6, 795–806 (1948).
Consden, R., A. H. Gordon and A. J. P. Martin: Qualitative analysis of proteins: a partition chromatographic method using paper. Biochemic. J. 38, 224–232 (1944).
Craig, L. C.: Identification of small amounts of organic compounds by distribution studies. J. biol. Chem. 155, 519–534 (1944).
Dale, H. H.: Nomenclature of fibres in the autonomic system and their effects. J. of Physiol. 80, 10–11 (1934).
D'Silva, J. L.: Action of adrenaline-like substances on the serum potassium. J. of Physiol. 108, 218–225 (1949).
Easson, L. H., and E. Stedman: Studies on the relationship between chemical constitution and physiological action. Biochemic. J. 27, 1257–1266 (1933).
Engel, A., and U. S. v. Euler: To be published.
Euler, U. S. v.: The presence of a substance with sympathin E properties in spleen extracts. Acta physiol. scand. (Stockh.) 11, 168–186 (1946a).
—The presence of a sympathomimetic substance in extracts of mammalian heart. J. of Physiol. 105, 38–44 (1946b).
—A specific sympathomimetic ergone in adrenergic nerve fibres (sympathin) and its relation to adrenaline and noradrenaline. Acta physiol. scand. (Stockh.) 12, 73–97 (1946c).
—Identification of the sympathomimetic ergone in adrenergic nerves of cattle (sympathin N) with laevo-noradrenaline. Acta physiol. scand. (Stockh.) 16, 63–74 (1948c).
—Preparation, purification and evaluation of noradrenaline and adrenaline in organ extracts. Arch. internat. Pharmacodynamie 77, 477–485 (1948d).
—Sympathin E and noradrenaline. Science (Lancaster, Pa.) 107, 422 (1948e).
—Noradrenalin und Histamin als Wirkstoffe vegetativer Nerven. Z. Vitamin-, Hormon-u. Fermentforschg 2, 596–608 (1948/49).
—Histamine as a specific constituent of certain autonomic nerve fibres. Acta physiol. scand. (Stockh.) 19, 85–93 (1949a).
—The distribution of sympathin N and sympathin A in spleen and splenic nerves of cattle. Acta physiol. scand. (Stockh.) 19, 207–214 (1949b).
Euler, U. S. v.: To be published. 1950.
—, and A. Åström: Liberation of histamine and sympathin by stimulation of isolated splenic nerves from cattle. Acta physiol. scand. (Stockh.) 16, 97–104 (1948).
—, and U. Hamberg: Colorimetric determination of noradrenaline and adrenaline. Acta physiol. scand. (Stockh.) 19, 74–84 (1949a).
— Colorimetric estimation of noradrenaline in the presence of adrenaline. Science (Lancaster, Pa.) 110, 561 (1949b).
— l-nor-Adrenaline in the suprarenal medulla. Nature (Lond.) 163, 642–643 (1949c).
— , and A. Purkhold: Noradrenaline and adrenaline in the suprarenals of the guinea-pig. Experientia 5, 451 (1949).
Euler, U. S. v., and S. Hellner: To be published.
Euler, U. S. v., and B. Hökfelt: To be published.
—, and G. Liljestrand: Die Wirkung des Adrenalins auf das Minutenvolumen des Herzens beim Menschen. Skand. Arch. Physiol. (Berl. u. Lpzg.) 52, 243–252 (1927).
— Observations on the pulmonary arterial blood pressure in the cat. Acta physiol. scand. (Stockh.) 12, 301–320 (1946).
—, and R. Luft: Acta Endocrinolog. 3, 323–330 (1949).
—, and C. G. Schmiterlöw: Sympathomimetic activity in extracts of normal human and bovine blood. Acta physiol. scand. (Stockh.) 13, 1–8 (1947).
Ewins, A. J.: Some colour reactions of adrenaline and allied bases. J. of Physiol. 40, 317–326 (1910).
Farrerons-Co., F.: Sobre el antagonismo regulador histamina-simpatina, — Sobre los efectos antihistaminicos de la simpatina E. Rev. espan. Fisiol. 4, 57–71, 73–78 (1948).
Finkleman, B.: On the nature of inhibition in the intestine. J. of Physiol. 70, 145–157 (1930).
Folkow, B., J. Frost and B. Uvnäs: Action of acetylcholine, adrenaline and noradrenaline on the coronary blood flow of the dog. Acta physiol. scand. (Stockh.) 17, 201–205 (1949).
—, and B. Uvnäs: The chemical transmission of vasoconstrictor impulses to the hind limbs and the splanchnic region of the cat. Acta physiol. scand. (Stockh.) 15, 365–388 (1948).
— The chemical transmission of vasoconstrictor impulses to the hind limbs of the dog. Acta physiol. scand. (Stockh.) 17, 191–194 (1949).
Gaddum, J. H., and L. G. Goodwin: Experiments on liver sympathin. J. of Physiol. 105, 357–369 (1947).
—, M. A. Khayyal and H. Rydin: The release of pharmacologically active substances by nerve trunks during electrical stimulation. J. of Physiol. 89, 9–10 (1937).
—, and H. Kwiatkowski: The action of ephedrine. J. of Physiol. 94, 87–100 (1938).
—, and H. Schild: A sensitive physical test for adrenaline. J. of Physiol. 80, 9–10 (1934).
—, W. S. Peart and M. Vogt: The estimation of adrenaline and allied substances in blood. J. of Physiol. 108, 467–481 (1949).
Garcia de Jalon, P., J. Bayo Bayo and M. Garcia de Jalon: Farmacoterapia actual (1945).
Gaskell, J. F.: Adrenaline in annelids. J. gen. Physiol. 2, 73–85 (1919).
Gley, P.: Action adrénolytique mais non sympatholytique de la corynanthine. Arch. néerl. Physiol. 28, 462–465 (1947).
Goldenberg, M., K. L. Pines, E. F. Baldwin, D. G. Greene and C. E. Roh: The hemodynamic response of man to norepinephrine and epinephrine and its relation to the problem of hypertension. Amer. J. Med. 5, 792–806 (1948).
Goldenberg, M., M. Faber, E. J. Alston and E. C. Chargaff: Evidence for the occurrence of nor-epinephrine in the adrenal medulla. Science (Lancaster, Pa.) 109, 534–535 (1949).
Goodall, McCh.: The presence of noradrenaline, adrenaline, and an unknown sympathiocolytic factor in cattle heart. Acta Physiol scand. (Stockh.) 20, 137–151 (1950).
Goodall, McCh.: Dihydroxyphenylalanine and hydroxytyramine in mammalian suprarenals. Acta Chemica Scand. (Stockh.) 1950b.
Goodall, McCh.: To be published. 1950.
Green, D. E., and D. Richter: Adrenaline and adrenochrome. Biochemic. J. 31, 596–616 (1937).
Greer, C. M., O. J. Pinkston, J. H. Baxter and E. S. Brannon: Nor-epinephrine (-[3,4-dihydroxyphenyl]-β-hydroxyethylamine) as a possible mediator in the sympathetic division of the autonomic nervous system. J. of Pharmacol. 62, 189–227 (1938).
Harley-Mason, J.: The structure of adrenochrome and its reduction products. Experentia 4, 307–308 (1948).
Heard, R. D., and H. S. Raper: VI. A study of the oxidation of 3∶4-dihydroxyphenyl-N-methylanine with reference to its possible function as a precursor of adrenaline. Biochemic. J. 27, 36 (1933).
Heinrich, P., and W. Schuler: Demonstration der kolorimetrischen Bestimmung von Adrenalin und Arterenol nebeneinander. Helvet. chim. Acta 7, C.36–C.37 (1949).
Heymans, C., J. J. Bouckaert, U. S. v. Euler and L. Dautrebande: Sinus carotidients et réflexes vasomoteurs. Arch internat. Pharmacodynamie 43, 86–110 (1932).
Hillarp, N.-Å.: Structure of the synapse and the peripheral innervation apparatus of the autonomic nervous system. Acta Anatomica, Suppl. 4 (1946).
Hoffmann, F., E. J. Hoffmann, S. Middleton and J. Talesnik: The stimulating effect of acetylcholine on the mammalian heart and the liberation of an epinephrine-like substance by the isolated heart. Amer. J. Physiol. 144, 189–198 (1945).
Hökfelt, B.: To be published. 1950.
Holton, P.: Noradrenaline in adrenal medullary tumours. Nature (Lond.) 163, 217 (1949).
Holtz, P., and K. Credner: Die enzymatische Entstehung von Oxytyramin im Organismus und die physiologische Bedeutung der Dopadecarboxylase. Arch. exper. Path. u. Pharmakol. 200, 356–388 (1942).
— and G. Kroneberg: Über das sympathicomimetische pressorische Prinzip des Harns („Urosympathin⌉"). Arch. exper. Path. u. Pharmakol. 204, 228–243 (1947).
—, R. Heise and K. Lüdtke: Fermentativer Abbau von 1-dioxyphenylalanin (Dopa) durch Niere. Arch. exper. Path. u. Pharmakol. 191, 87–118 (1938/39).
—, and H. J. Schümann: Arterenol — ein neues Hormon des Nebennierenmarks. Naturwiss. 35, 159 (1948a).
— Über das Vorkommen von Arterenol in den Nebennieren. Naturwiss. 35, 191–192 (1948b).
— Karotissinusentlastung und Nebennieren. Arterenol chemischer Überträgerstoff sympathischer Nervenerregungen und Hormon des Nebennierenmarks. Arch. exper. Path. u. Pharmakol. 206, 49–64 (1949).
Houssay, B. A., and R. Gerschman: Glucogenolisis hepática por adrenalina y simpatina en saposnormales e hipofisoprivos. Rev. Soc. argent. Biol. 23, 72–80 (1947).
James, W. O.: Demonstration and separation of noradrenaline, adrenaline and methyladrenaline. Nature (Lond.) 161, 851–852 (1948).
Kappert, A., G. C. Sutton, A. Reale, K. H. Skoglund and G. Nylin: The clinical response of human beings to 1-noradrenaline and its clinical applicability. Acta Cardiologica 5, 121–136 (1950).
Kendall, E. C.: Hormones of the adrenal cortex. Endocrinology 30, 853–860 (1942).
Klopp, C. T.: The reactions of partially denervated smooth muscle to adrenaline and sympathin. Amer. J. Physiol. 130, 475–480 (1940).
Konschegg, Th.: Ursachen der Hypertonie. Wien. klin. Wschr. 1940, 269–273.
Konzett, H., and C. O. Hebb: Vaso-and bronchomotor actions of noradrenaline (arterenol) and of adrenaline in the isolated perfused lungs of the dog. Arch. internat. Pharmacodynamie 73, 210–224 (1949).
Kutschera-Aichbergen, H. v.: Die Überfunktion und die Unterfunktion der Nebennieren. Schweiz. med. Wschr. 1948, 135–140.
Lissák, K.: Effects of extracts of adrenergic fibres on the frog heart. Amer. J. Physiol. 125, 778–785 (1939a).
—Liberation of acetylcholine and adrenaline by stimulating isolated nerves. Amer. J. Physiol. 127, 263–271 (1939b).
Loewi, O.: Über humorale Übertragbarkeit der Herzennervenwirkung. Arch. ges. Physiol. 189, 239–242 (1921).
—Über den Adrenalingehalt des Säugerherzens. Arch. internat. Pharmacodynamie 57, 139–140 (1937).
Luco, J. V. and F. Goni: Synaptic fatigue and chemical mediators of postganglionic fibers. J. Neurophysiol. 11, 498–500 (1948).
—, and K. Lissák: Chemical mediators in the aqueous humor. Amer. J. Physiol. 124, 271–278 (1938).
Ludueña, F. P., E. Ananenko, O. H. Siegmund and Ll. C. Miller: Comparative pharmacology of the optical isomers of arterenol. J. of Pharmacol. 95, 155–169 (1949).
Luft, R., B. Sjögren and O. Cassmer: To be published.
Lund, A.: Simultaneous fluorimetric determination of adrenaline and noradrenaline in blood. Acta Pharmacol. et toxicol. scand. 1950.
Lundholm, L.: The effect of 1-noradrenaline and ergotamine on the oxygen consumption of guinea-pigs. Acta physiol. scand. (Stockh.) 18, 341–354, (1949).
Malméjac, J., et G. Chardon: Mécanisme de déclenchement et d'entretien de la sécrétion surrénale d'adrenaline en anoxie. C. r. Soc. Biol. Paris 141, 395–396 (1947).
Marrazzi, A. S., and R. N. Marrazzi: Chemical structure and the definition of sympathin E. Science (Lancaster, Pa.), 106, 520–521 (1947).
Marsh, D. F., and E. J. van Liere: The effect of adrenergic blocking agents on the vasoconstriction produced by acute oxygen lack. J. of Pharmacol. 94, 221–223 (1948).
Meier, R., and H. J. Bein: Der Einfluß der Nebenniere auf die Kreislaufwirkung des Adrenalines. Experientia 4, 358 (1948).
Melville, K. J.: Antisympathomimetic action of dioxane compounds (F 883 and F 933), with special reference to vascular responses to dihydroxyphenyl ethanolamine (arterenol) and nerve stimulation. J. of Pharmacol. 59, 317–327 (1937).
Morton M. C., and M. L. Tainter: Effects of sympathomimetic amines on perfused blood vessels. J. of Physiol. 98, 263–282 (1940).
Nasmyth, P. A.: The effect of some sympathomimetic amines on the ascorbic acid content of rats' adrenal glands. J. of Physiol. 110, 294–300 (1949).
Nisell, O.: Acta Physiol scand. (Stockh.) Suppl. 73 (1950).
Norlander, O.: To be published.
Östlund, E.: To be published 1950.
Page, I. H.: Personal communication.
Peart, W. S.: The nature of splenic sympathin. J. of Physiol. 108, 491–501 (1949).
Pekkarinen, A.: unpublished. 1949.
Porat, B. v., and U. S. v. Euler: unpublished.
Raab, W.: The pathogenic significance of adrenaline and related substances in the heart muscle. Exper. med. Surg. 1, 188–225 (1943a).
—Adrenaline and related substances in blood and tissues. Biochemic. J. 37, 470–473 (1943b).
Raab, W., and Lepeschkin: Unpublished.
Rein, H., O. Mertens, u. F. G. Valdecasas: Gefäßwirkungen des Adrenalins im ruhenden und arbeitenden Muskel. Pflügers Arch. 237, 454–475 (1936).
Rexed, B.: Personal communication.
Richter, D.: The inactivation of adrenaline in vivo in man. J. of Physiol. 98, 361–374 (1940).
—, and F. C. MacIntosh:Adrenaline ester. Amer. J. Physiol. 135, 1–5 (1941)
Rosenblueth, A., and T. Schlossberg: The sensitization of vascular response to „sympathin” by cocaine and the quantitation of „sympathin” in terms of adrenaline. Amer. J. Physiol. 97, 365–374 (1931).
Rydin, H.: The influence of different temperatures on the action of drugs on autonomic effector cells. Acta physiol. scand. (Stockh.) 11, 270–278 (1946).
Schäfer, H.: To be published 1950.
Scheiner, H.: Action hypertensive des extraits de rate sur le chien atropinisé et cocainisé. C. r. Soc. Biol. Paris 124, 877–879 (1937a).
—Effects hypertenseurs produits par l'excitation du nerf splénique chez le chien atropinisé et cocainisé. C. r. Soc. Biol. Paris 124, 1219 (1937b).
Schild, H.: Adrenaline in the suprarenal medulla. J. of Physiol. 99, 455–469 (1933).
Schmiterlöw, C.: The nature and occurrence of pressor and depressor substances in extracts from blood vessels. Acta physiol. scand. (Stockh.), Suppl., 16, 1–113 (1948).
Schuler, W., and P. Heinrich: Adrenalin und Arterenol im Nebennierenmark verschiedener Tiere. Helv. physiol. pharm. Acta 7, 515–519 (1949).
Schültz: Publ. Health Marine Hosp. Bull. Washington 1909, No 55.
Schümann, H. J.: Über die Wirkung von Nebennierenextrakten auf Blutdruck und Blutzucker. Arch. exper. Path. u. Pharmakol. 206, 475–483 (1949).
Shaw, F. H.: The estimation of adrenaline. Biochemic. J. 32, 19–25 (1938).
Stehle, R. L., and H. C. Ellsworth: Dihydroxyphenyl ethanolamine (arterenol) as a possible sympathetic hormone. J. of Pharmacol. 59, 114 (1937).
Stolz, F.: Über Adrenalin und Alkylaminoacetobrenzcatechin. Ber. dtsch. chem. Ges. 37, 4149–4153 (1904).
Swan, H. J. C.: Effect of noradrenaline on the human circulation. Lancet 257, 508–510 (1949).
Tainter, M. L.: Comparative actions of sympathomimetic compounds: catechol derivatives, and possible mechanism of the sensitization-desensitization phenomena of cocaine. Arch. internat. Pharmacodynamie 41, 365–376 (1931).
—, J. R. Pedden and M. James: Comparative actions of sympathomimetic compounds: Bronchodilator actions in perfused guinea pig lungs. J. Pharmacie 51, 371–386 (1934).
—, B. F. Tullar and F. P. Luduena: Levo-Arterenol. Science (Lancaster, Pa.) 107, 39–40 (1948).
Thibault, O.: Adrénaline et sympathine, Action de la nor-Adrénaline sur la consommation d'Oxygéne du Rat blanc. C. r. Soc. Biol. Paris 142, 47–50 (1948).
Tullar, B. F.: The resolution of dl-arterenol. J. amer. chem. Soc. 70, 2067–2068 (1948).
—The separation of 1-arterenol from natural U.S.P. epinephrine. Science (Lancaster, Pa.) 109, 536–537 (1949).
Utterback, R. A.: The innervation of the spleen. J. comp. Neur. 81, 55–68 (1944).
Verly, W.: La réactif arsénomolybdique permet-il de reconnaitre l'adrénaline et l'artérénol dans les extraits tissulaires. Arch. internat. Physiol. 55, 397–408 (1948a).
—Lévo-artérénol et artérénol racémique. Arch. internat. Physiol. 55, 409–411 (1948b).
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v. Euler, U.S. (1950). Noradrenaline (Arterenol), adrenal medullary hormone and chemical transmitter of adrenergic nerves. In: Ergebnisse der physiologie biologischen chemie und experimentellen pharmakologie. Ergebnisse der Physiologie, biologischen Chemie und experimentellen Pharmakologie, vol 46. Springer, Berlin, Heidelberg. https://doi.org/10.1007/BFb0112430
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