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Mutational analysis of rhodotorulic acid synthesis in Rhodotorula pilimanae

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Siderophores from Microorganisms and Plants

Part of the book series: Structure and Bonding ((STRUCTURE,volume 58))

Abstract

The current status of research on the aerobactin gene complex of Escherichia coli has been reviewed from the standpoint of its organization and regulation. The reasons for selection of the basidiomycetous yeast, Rhodotorula pilimanae, as the most suitable eukaryotic species to which to extend similar studies have been enumerated. A convenient bio-assay is described for detection of mutants of Rhodotorula pilimanae blocked in the biosynthesis of rhodotorulic acid. The application of the bio-assay to a mutagenized culture of Rhodotorula pilimanae enabled collection of a series of mutants, one of which forms an altered version of the constituent amino acid of rhodotorulic acid, Nδ-acetyl-Nδ-hydroxyornithine.

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VIII. References

  1. Jacobs, A., Worwood, A. (eds.): Iron in Biochemistry and Medicine, Academic Press, London 1980

    Google Scholar 

  2. Neilands, J.: Ann. Rev. Nutr. 1, 27 (1981)

    Article  CAS  Google Scholar 

  3. Neilands, J. B.: Ann. Rev. Biochem. 50, 715 (1981)

    Article  CAS  Google Scholar 

  4. Bindereif, A., Neilands, J. B.: J. Bacteriol. 153, 111 (1983)

    Google Scholar 

  5. Bindereif, A., Thorsness, P. E., Neilands, J. B.: Inorganica Chemica Acta — Bioinorganic Chemistry 79, 78 (1983)

    Google Scholar 

  6. Bindereif, A., Baun, V., Hantke, K.: J. Bacteriol. 150, 1472 (1982)

    CAS  Google Scholar 

  7. Grewal, K. K., Warner, P. J., Williams, P. H.: FEBS Lettr. 140, 27 (1982)

    Article  CAS  Google Scholar 

  8. Van Tiel-Menkveld, G. J., Mentjox-Vervuurt, J. M., Oudega, B., DeGraff, F. K.: J. Bacteriol. 150, 490 (1982)

    Google Scholar 

  9. Bindereif, A., Neilands, J. B.: J. Biol. Chem., submitted

    Google Scholar 

  10. Bagg, A., Neilands, J. B.: Abstr. 84th Ann. Meeting, Am. Soc. Microbiol., St. Louis, MO, Mar. 4–9 (1984)

    Google Scholar 

  11. Takeda, Y., Ohlendorf, D. H., Anderson, W. F., Matthews, B. W.: Science 221, 1020 (1983)

    Article  CAS  Google Scholar 

  12. Anderson, W. F., Cygler, M., Vandonselaar, M., Ohlendorf, D. H., Matthews, B. W., Kim, J., Takeda, Y.: J. Mol. Biol. 168, 903 (1983)

    Article  CAS  Google Scholar 

  13. Klebba, P. E., McIntosh, M. A., Neilands, J. B.: J. Bacteriol. 149, 880 (1982)

    CAS  Google Scholar 

  14. Laird, A. J., Ribbons, D. W., Woodrow, G. C., Young, I. G.: Gene 11, 347 (1980)

    Article  CAS  Google Scholar 

  15. Laird, A. J., Young, I. G.: ibid. 11, 359 (1980)

    Article  CAS  Google Scholar 

  16. Atkin, C. L., Neilands, J. B.: Biochemistry 7, 3734 (1968)

    Article  CAS  Google Scholar 

  17. Widmer, J., Keller-Schierlein, W.: Helv. Chim. Acta 52, 388 (1969)

    Article  Google Scholar 

  18. Isowa, Y., Takashima, T., Ohmori, M., Kurita, H., Sato, M., Mori, K.: Bull. Chem. Soc. Japan 45, 1467 (1972)

    Article  CAS  Google Scholar 

  19. Fujii, T., Hatanaka, Y.: Tetrahedron 29, 3825 (1973)

    Article  CAS  Google Scholar 

  20. Atkin, C. L., Neilands, J. B., Phaff, H. J.: J. Bacteriol. 103, 722 (1970)

    CAS  Google Scholar 

  21. Akers, H. A., Neilands, J. B.: In Biological Oxidation of Nitrogen, (Gorrod, J. W., ed.), Elsevier North Holland, Amsterdam, p. 429 (1978)

    Google Scholar 

  22. Widmer, J., Keller-Schierlein, W.: Helv. Chim. Acta 57, 1904 (1974)

    Article  CAS  Google Scholar 

  23. Akers, H. A.: Doctoral Dissertation, Univ. of California, Berkeley 1974

    Google Scholar 

  24. Hantke, K.: Mol. Gen. Cenet. 191, 301 (1983)

    Article  CAS  Google Scholar 

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Author notes

  1. Alexander Liu

    Present address: Harvard Medical School, 02115, Boston, MA

Authors and Affiliations

  1. Department of Biochemistry, University of California, 94720, Berkeley, CA

    Alexander Liu & J. B. Neilands

Authors
  1. Alexander Liu
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  2. J. B. Neilands
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© 1984 Springer-Verlag

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Liu, A., Neilands, J.B. (1984). Mutational analysis of rhodotorulic acid synthesis in Rhodotorula pilimanae . In: Siderophores from Microorganisms and Plants. Structure and Bonding, vol 58. Springer, Berlin, Heidelberg. https://doi.org/10.1007/BFb0111312

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  • DOI: https://doi.org/10.1007/BFb0111312

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-13649-1

  • Online ISBN: 978-3-540-39028-2

  • eBook Packages: Springer Book Archive

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