Abstract
Current views on the structure and function of biological membranes imply a great variety of dynamical aspects. These range from the dynamic phase behaviour of phospholipids and conformational variations of membrane proteins during membrane-associated processes, to the interactions between membranes in fusion and pore formation. The structural description of these processes, many of which imply the possibility of intermediate structures, calls for fast time-resolved diffraction methods, i.e. the cinematographic approach. The present article gives first an overview on the specific problems and the theories for their solution in X-ray diffraction on membranes, and then reviews the present possibilities of time-resolved structural studies using synchrotron radiation on phospholipid model systems and functional membranes (sarcoplasmic reticulum membrane). It is shown that such studies bear great promise in entering the millisecond time domain and bridging the existing gap between static structural information and the wealth of dynamic data derived from spectroscopic methods.
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7 References
Worthington CR (1973) X-ray diffraction studies on biological membranes, in: Current Topics in Bioenergetics, Vol. V (eds) Sanadi DR, Packer L, p. 1, New York, Academic Press
Shipley GG (1973) Recent X-ray diffraction studies of biological membranes and membrane components, in: Biological Membranes, Vol. II (eds) Chapman D, Wallach DFH, p. 1, London, Academic Press
Franks NP, Levine YK (1981) Low-angle X-ray diffraction, in: Membrane Spectroscopy (ed) Grell E, p. 437, Springer, Berlin
Blaurock AE (1982) Biochim. Biophys. Acta 650: 176
Blaurock AE (1975) J. Mol. Biol. 93: 139
Henderson R (1975) ibid. 93: 123
Kirschner DA, Kaspar DLD (1977) Diffraction studies of molecular oganization, in: Myelin (ed) Morele P, p. 154, New York, Plenum Press
Worthington CR (1973) Exp. Eye Res. 17: 487
Chabre M (1975) Biochim. Biophys. Acta 382: 322
Kreuz W (1972) Angew. Chem. (Int. Ed.) 11: 551
Finean JB, Coleman R, Kuntton S, Limbrick AR, Thompson JE (1968) H. Gen. Physiol. 51: 19s
Dupont Y, Harrison SC, Hasselbach W (1973) Nature 244: 555
Herbette L, Marquardt J, Scarpa A, Blasie JK (1977) Biophys. J. 20: 245
Thomson JE, Coleman R, Finean JB (1968) Biochim. Biophys. Acta 150: 405
Limbrick AR, Fineman JB (1970) J. Cell. Sci. 7: 373
Wilkins MHF, Blaurock AE, Engelman DM (1971) Nature New Biol. 230: 72
Luzzati V (1968) X-ray diffraction studies of lipid-water systems, in: Biological Membranes, Vol. I (ed) Chapman D, p. 71, New York, Academic Press
Luzzati V, Tardieu A (1974) Ann. Rev. Phys. Chem. 79
Hauser H, Pascher I, Pearson RH, Sundell S (1981) Biochim. Biophys. Acta 650: 21
Kratky O, Glatter O (1982) Small-Angle X-Ray Scattering, London, Academic Press
Kratky O, Laggner P (1987) X-ray small angle scattering, in: Meyers RA (ed) Encyclopedia of Physical Science and Technology, Vol. 14, p. 693, New York, Academic Press
Sardet C, Tardieu A, Luzzati V (1976) J. Mol. Biol. 105: 383
Beverley Osborne H, Sardet C, Michel-Villaz M, Chabre M (1978) ibid. 123: 177
Le Maire M, Møller JV, Tardieu A (1981) ibid. 150: 273
Pachence JM, Edelman IS, Schoenborn BP (1987) J. Biol. Chem. 262: 702
Deisenhofer J, Epp O, Mike K, Huber R, Michel M (1984) J. Mol. Biol. 180: 385
Sherwood D (1976) Crystals, X-Rays and Proteins, London, Longman
Alexander LE (1969) X-Ray Diffraction Methods in Polymer Science, New York, Wiley-Interscience
Kratky O, Porod G (1948) Acta Phys. Austriaca 2: 133
Porod G (1948) ibid. 2: 255
Hosemann R, Bagchi SN (1962) Direct Analysis of Diffraction by Matter, Amsterdam, North-Holland
Bradaczek H, Luger P (1978) Acta Cryst. A34: 681
Pape EH (1974) Biophys. J. 14: 284
Pape EH, Kreuz W (1978) J. Appl. Cryst. 11: 421
Glatter O, Hainisch B (1984) ibid. 17: 435
Glatter O (1981) ibid. 14: 101
King GI (1975) Acta Cryst. A31: 130
Mitsui T (1978) Adv. Biophys. 10: 97
Blaurock AE (1971) J. Mol. Biol. 56: 35
Sayre D (1952) Acta Cryst. 5: 843
Franks NP (1976) J. Mol. Biol. 100: 345
Franks NP, Arunchalam T, Caspi E (1978) Nature 276: 530
Lesslauer W, Blasie JK (1972) Biophys. J. 12: 175
Moody MF (1974) ibid. 14: 697
Zernike F, Prins JA (1927) Z. Physik 41: 184
Kratky O (1933) Physik Z. 34: 482
Worthington CR (1986) Biophys. J. 49: 98
Blaurock AE, Nelander JC (1976) J. Mol. Biol. 103: 421
Tardieu A, Luzzati V, Reman RC (1973) ibid. 75: 711
Janiak MJ, Small DM, Shipley GG (1976) Biochemistry 15: 4575
Abrahamsson S, Dahlén B, Löfgren H, Pascher I (1978) Progr. Chem. Fats other Lipids 16: 125
Cullis P, De Kruijff B (1979) Biochim. Biophys. Acta 559: 393
De Kruijff B, Cullis P, Verkleij A, Hope MJ, Van Echteld CJA, Taraschi TF, Van Moogevast P, Killian JA, Rietveld A, Van Der Steen ATM Modulation of lipid polymorphism by lipid-protein interactions, in: “Progress in Protein-Lipid Interactions” Vol. I Watts A, De Pont JJHHM (eds) 1985 p. 89, Amsterdam, Elsevier
Caffrey M, Bilderback DM (1984) Biophys. J. 45: 627
Laggner P FEBS Advanced Course “Structure and Dynamics of Membrane Lipids” April 1984, Zeist, Holland; Symp. on “New Methods in X-Ray Absorption, Scattering and Diffraction for Applications in Structural Biology”, Aug. 1984, Bristol U.K. Chance B, Bartunik HD (eds) (1986) Academic Press, London
Inoko Y, Mitsui T (1978) J. Phys. Soc. Japan 6: 1918
Ruocco MJ, Shipley GG (1982) Biochim. Biophys. Acta 691: 309
Tsong TY, Kanehisa MI (1977) Biochemistry 16: 2674
Gruenwald B (1982) Biochim. Biophys. Acta 687: 71
Lentz RB, Freire E, Biltonen RL (1978) Biochemistry 17: 4475
Cho KC, Choy CL, Young K (1981) Biochim. Biophys. Acta 663: 14
Stumpel J, Eibl H, Niksch A (1983) ibid. 727: 246
Gottlieb MH, Eanes ED (1974) Biophys. J. 14: 335
Boulin C, Gabriel A, Hendrix J (1984) Research Report EMBL 1983, p. 135, EMBL Heidelberg
Bordas J, Mandelkow E In: Fast Methods in Physical Biochemistry and Cell Biology, Sha'afi RI, Fernandez SM (eds) (1983) p. 137, Elsevier, Amsterdam
Caffrey M (1985) Biochemistry 24: 4826
Rand RP, Chapman D, Larsson K (1975) Biophys. J. 15: 1117
Kashchiev D (1984) Crystal Res. Technol. 19: 1413
Wunderlich B (1976) Macromolecular Physics, Vol. 2, Crystal Nucleation, Growth, Annealing, p. 7, New York, Academic Press
Dr Kruijff B, Verkleij AJ, Van Echteld CJA, Gerritsen WC, Mombers C, Noordam PC, De Gier J (1979) Biochim. Biophys. Acta 555: 200
Hui SW, Stewart TP, Boni LT (1983) Chem. Phys. Lipids 33: 113
Siegel CP (1984) Biophys. J. 45: 399
Siegel DP (1986) ibid 49: 1155
Laggner P, Lohner K to appear in Chem. Phys. Lipids
Ranck J-L, Letellier L, Shechter E, Krop B, Pernod P, Tardieu A (1984) Biochemistry 23: 4955
Lucy JA Biomembrane fusion, in: Biological Membranes, Vol 4 Chapman D (ed) (1982) p. 367, Academic Press, London
Siegel DP Membrane-membrane interactions in lamellar-to-inverted hexagonal phase transitions, in: Membrane Fusion Sowers AE (ed) Plenum, New York; in the press
Ebashi S, Endo M, Ohtsuki IQ (1969) Rev. Biophys. 2: 351
Meissner G, Conner GE, Fleischer S (1973) Biochim. Biophys. Acta 298: 246
Herbette LG, De Floor P, Fleischer S, Pascalini D, Scarpa A, Blasie JK (1985) ibid. 817: 103
Pierce D, Scarpa A, Trentham DR, Tapp MR, Blasie JK (1983) Biophys. J. 44: 365
McCray JA, Herbette LG, Kihava T, Trentham DR (1980) Proc. Natl. Acad. Sci. USA 77: 7237
Laggner P, Ludi H, Hasselbach W in preparation
Laggner P, Glatter O, Müller K, Kratky O, Kostner G, Holasek A (1977) Eur. J. Biochem. 77: 165
Blasie JK, Herbette LG, Pascolini D, Skita V, Pierce DH, Scarpa A (1985) Biophys. J. 48: 9
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dedicated to Professor Otto Kratky on the occasion of his eightyfifth birthday.
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Laggner, P. (1988). X-ray studies on biological membranes using synchrotron radiation. In: Synchrotron Radiation in Chemistry and Biology I. Topics in Current Chemistry, vol 145. Springer, Berlin, Heidelberg. https://doi.org/10.1007/BFb0111240
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DOI: https://doi.org/10.1007/BFb0111240
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