Abstract
In this paper we treat the interaction of acidic-glycolipids with proteins. We used monosialoganglioside, disialoganglioside, and ganglioside mixture. The proteins used were albumins whose surfaces are modified differently with mono- and disaccharides. By using X-ray and neutron-scattering techniques we have found that the interactions of mono- and disialogangliosides with albumins having monosaccharides occur less destructively for ganglioside aggregate structures at low protein concentrations and that the interaction of monosialogangliosides with albumins having disaccharides occurs very destructively, suggesting a strong interaction between them compared with other cases.
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References
Svennerholm L. Asbury AK, Reisfeld RA, Sandhoff K, Suzuki K, Tettamanti G, Toffano G (eds) (1994) Biological Function of Gangliosides. Eisevier. Amsterdam
Tettamanti G, Sonnion S, Ghidoni R, Masserini M, Venerando B (1985) In: Corti M, Degiorgio V (eds) Physics of Amphiphiles: Micelles, Vesicles and Microemulsions. North-Holland, Amsterdam, pp 607–636
Sonnion S, Cantù L, Corti M, Acquotti D, Venerando B (1994) Chem Phys Lipids 71:21–45
Hirai M, Takizawa T, Yabuki S, Nakata Y, Hayashi K (1996) Biophys J 70:1761–1768
Hirai M, Takizawa T, Yabuki S, Hirai T, Hayashi K (1996) J Phys Chem 100:11675–11680
Hirai M, Takizawa T, Yabuki S, Hayashi K (1996) J Chem Soc Faraday Trans 92:4533–4540
Hirai M, Takizawa T, Yabuki S, Nakata Y, Mitomo H, Hirai T, Shimizu S, Kobayashi K, Furusaka M, Hayashi K (1995) Physica B 213, 214:751–753
Takizawa T, Hirai M, Yabuki S, Nakata Y, Takahashi A, Hayashi K (1995) Thermochim Acta 267:355–364
Gammack DB (1963) Biochem J 88:373–383
Furusaka M, Suzuya K, Watanabe N, Osawa M, Fujikawa I, Satoh S (1992) KEK Progress Report 92-2:25–27
Glatter O (1982) In: Glatter O and Kratky O (eds) Small Angle X-Ray Scattering. Academic Press, London, pp 119–196
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© 1997 Steinkopff Verlag
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Hirai, M., Takizawa, T., Yabuki, S., Nakata, Y., Arai, S., Furusaka, M. (1997). Structural study of protein-ganglioside interaction. In: Kawasaki, K., Lindman, B., Okabayashi, H. (eds) Formation and Dynamics of Self-Organized Structures in Surfactants and Polymer Solutions. Progress in Colloid & Polymer Science, vol 106. Steinkopff. https://doi.org/10.1007/BFb0111066
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DOI: https://doi.org/10.1007/BFb0111066
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Publisher Name: Steinkopff
Print ISBN: 978-3-7985-1096-8
Online ISBN: 978-3-7985-1659-5
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