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Neutron scattering study of phosphatidylinositol 4,5-bis(phosphate) aqueous dispersion

  • Biocolloids
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Formation and Dynamics of Self-Organized Structures in Surfactants and Polymer Solutions

Part of the book series: Progress in Colloid & Polymer Science ((PROGCOLLOID,volume 106))

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Abstract

In this paper we treat the thermotropic phase behavior of phosphatidylinositol 4,5-bis(phosphate) (PIP2) aggregates in aqueous solution. By using the solvent contrast variation method in neutron small-angle scattering we could determine the absolute value of the PIP2 molecular volume in the micellar form from the contrast matching point. The shift of the contrast matching point indicates the increase of the PIP2 molecular volume of ∼11% with elevating temperature from 10 °C to 50 °C. The decrease of the gyration radius of the PIP2 micelle observed in the present experiments well agrees with our previous results of X-ray scattering study. The present results suggest that the increase of the molecular volume would be mainly attributable to the change of the hydrophilic polar head region to decrease the critical packing parameter.

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Abbreviations

N-(2-hydroxyethyl)piperazine-N′-(2-ethanesulfonic acid):

HEPES

Ethylenediaminetetraacetic acid:

EDTA

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Authors and Affiliations

  1. Department of Physics, Gunma University, 4-2 Aramaki, 371, Maebashi, Japan

    Dr. M. Hirai, S. Yabuki, T. Takizawa & K. Hayashi

  2. Institute for Solid State Physics, University of Tokyo, 106-1, Tokai, Japan

    M. Imai & Y. Matsushita

  3. Faculty of Education, Yamanashi University, 400, Koufu, Japan

    Y. Ito

Authors
  1. Dr. M. Hirai
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  2. S. Yabuki
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  3. T. Takizawa
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  4. K. Hayashi
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  5. M. Imai
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  6. Y. Matsushita
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  7. Y. Ito
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Corresponding author

Correspondence to M. Hirai .

Editor information

K. Kawasaki B. Lindman H. Okabayashi

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© 1997 Steinkopff Verlag

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Hirai, M. et al. (1997). Neutron scattering study of phosphatidylinositol 4,5-bis(phosphate) aqueous dispersion. In: Kawasaki, K., Lindman, B., Okabayashi, H. (eds) Formation and Dynamics of Self-Organized Structures in Surfactants and Polymer Solutions. Progress in Colloid & Polymer Science, vol 106. Steinkopff. https://doi.org/10.1007/BFb0111065

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  • DOI: https://doi.org/10.1007/BFb0111065

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  • Publisher Name: Steinkopff

  • Print ISBN: 978-3-7985-1096-8

  • Online ISBN: 978-3-7985-1659-5

  • eBook Packages: Springer Book Archive

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