Diagnosis using photon diffusion: From brain oxygenation to the fat of the atlantic salmon
We present a new diagnostic method, based on optical measurements in the visible and near-infrared wavelength regime. This method has many advantages over current imaging and biopsy techniques. In order to understand and interpret the results of the measurements, a random-walk on a lattice is used to model photon diffusion in biological tissues. Applications of this method range from medicine (diagnosis of brain function (oxygenation) in neonates and early detection of breast tumors) to food science (non-destructive determination of fat and moisture content in Atlantic Salmon).
KeywordsBiological Tissue Average Path Length Turbid Medium Optical Biopsy Photon Trajectory
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- Ben-Avraham, D., Taitelbaum, H., Weiss, G.H. (1991): “Boundary conditions for a model of photon migration in a turbid medium,” Lasers Life Sci., 4, 29–36Google Scholar
- Gayen, S.K., Alfano, R.R. (1996): “Biomedical Imaging Techniques”, Optics and Photonics News, March 1996, pp. 17–22Google Scholar
- Rosen-Zvi, M., Taitelbaum, H. (1996): “Frequency-domain photon migration in two-layered tissues”, OSA TOPS on Biomedical Optical Spectroscopy and Diagnostics, 3, 101–104Google Scholar
- Taitelbaum, H. (1994): “Optical penetration depth in layered tissues”, OSA Proc. on Advances in Optical Imaging and Photon Migration, 21, 305–309Google Scholar
- Selected Papers on TISSUE OPTICS: Applications in Medical Diagnostics and Therapy (1994): V.V. Tuchin, Ed., SPIE Milestone Series, MS102Google Scholar
- Yodh, A., Chance, B. (1995): “Spectroscopy and Imaging with Diffusing Light”, Physics Today, March 1995, pp. 34–40Google Scholar