Abstract
The pinwheel-like arrangement of iso-orientation domains around orientation centers is a ubiquitous structural element of orientation preference maps in primary visual cortex. We show that activity-dependent self-organization of orientation preference implies that low densities of orientation centers develop through an initial overproduction and subsequent annihilation of pinwheels. Monitoring their density during development therefore offers a powerful novel approach to test whether orientation preference arises by activity-dependent mechanisms or is intrinsically predetermined. Observed interspecies differences in the density of orientation centers can be explained by a dynamic interaction of ocular dominance and orientation columns during development.
Keywords
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Preview
Unable to display preview. Download preview PDF.
References
Hubel, D. H. and Wiesel, T. N. J. Physiol. 160, 215–243 (1962).
Hubel, D. H. and Wiesel, T. N. J. Physiol. 160, 106–154 (1963).
von der Malsburg, C. Kybernetik 14, 85–100 (1973).
Nass, M. M. and Cooper, L. N. Biol. Cybernetics 19, 1–18 (1975).
Albus, K. and Wolf, W. J. Physiol. 348, 153–185 (1984).
Chapman, B. and Stryker, M. P., J. Neurosci. 13, 5251–5262 (1993).
Thompson, I. D., Kossut, M., and Blakemore, C. Nature 301, 712–715 (1983).
Chapman, B., Stryker, M. P., and Bonhoeffer, T., J. Neurosci. 16, 6443–6453 (1996).
Bonhoeffer, T. Arzneimittel-Forschung 45(1), 351–356 (1995).
Miller, K. D. J. Neuroscience 14(1), 409–441 (1994).
von der Malsburg, C. and Cowan, J. D., Biol. Cybernetics 45, 49–56 (1982).
Obermayer, K., Blasdel, G. G., and Schulten, K. Phys. Rev. A 45, 7568–7589 (1992).
Barlow, H. B. Nature 258, 199–204 (1975).
Movshon, J. and Sluyters, R. C. V. Ann. Rev. Psychol. 32, 447–522 (1981).
Singer, W. Science 270, 758–764 (1995).
Gödecke, I. and Bonhoeffer, T. Nature 379, 251–254 (1996).
Bonhoeffer, T. and Grinvald, A. Nature 353, 429–431 (1991).
Blasdel, G. G. J. Neurosci. 12, 3139–3161 (1992).
Bonhoeffer, T., Kim, D.-S., Malonek, D., Shoham, D., and Grinvald, A. Europ. J. Neurosci. 7, 1973–1988 (1995).
Bartfeld, E. and Grinvald, A. Proc. Natl. Acad. Sci. 89, 11905–11909 (1992).
Blasdel, G., Livingstone, M., and Hubel, D. J. Neuroscience 12, 1500 (1993).
Weliky, M. and Katz, L. C. J. Neurosci. 14, 7291–7305 (1994).
Fitzpatrick, D., Schofield, B. R., and Strote, J. In Soc. Neurosci. Abstracts, 837. Society for Neurosci., (1994).
Swindale, N. In Models of the Visual Cortex, Rose, D. and Dobson, V., editors, chapter 47, 452–461. Wiley, New York (1985).
Blasdel, G. G. Annu. Rev. Physiol. 51, 561–581 (1989).
Gödecke, I., Maldonado, P., Gray, C., and Bonhoeffer, T. In Göttinger Neurobiology Report 1996, Elsner, N. and Schnitzler, H.-U., editors, 412, (1996).
Obermayer, K. and Blasdel, G. G. Neural Computation 9, 555–575 (1997).
Rao, S., Toth, L., and Sur, M. J. Comp. Neurol. 387, 358–370 (1997).
Löwel, S., Freeman, B., and Singer, W. J. Comp. Neurol. 255, 401–415 (1987).
Bosking, W. H., Zhang, Y., Schofield, B. R., and Fitzpatrick, D. J. Neurosci. 17, 2112–2127 (1997).
LeVay, S. and Nelson, S. B. In Vision and Visual Dysfunction, chapter 11, 266–315. Macmillan, Houndsmill (1991).
Horton, J. C. and Hocking, D. R. J. Neurosci. 16, 5510–5522 (1996).
Humphrey, A., Skeen, L., and Norton, T. J. Comp. Neurol. 192, 544–566 (1980).
Hubel, D. H., Wiesel, T. N., and Stryker, M. J. Comp. Neurol. 177, 361–380 (1978).
Miller, K. D. In Models of Neural Networks III, Domany, E., Van Hemmen, J., and Schulten, K., editors. Springer-Verlag, NY (1995).
Swindale, N. Network 7, 161–247 (1996).
Adler, R. J. The Geometry of Random Fields. John Wiley, NY, (1981).
Halperin, B. I. In Physics of Defects, Les Houches, Session XXXV, 1980, Balian, R., Kléman, M., and Poirier, J.-P., editors (North-Holland, Amsterdam, 1981).
Wolf, F. and Geisel, T. Nature 395, 73–78 (1998).
Durbin, R. and Mitchinson, G. Nature 343, 644–647 (1990).
Erwin, E., Obermayer, K., and Schulten, K. Neural Comp. 7, 425–468 (1995).
Wiesel, T. N. and Hubel, D. H. J. Comp. Neurol. 158, 307–318 (1974).
Stryker, M. P. In Neurosci. Res. Prog. Bull., Vol. 15, No. 3, chapter VII, 454–462. MIT Press, Cambridge, Mass (1977).
Changeux, J.-P. and Danchin, A. Nature 264, 705–712 (1976).
Obermayer, K. and Blasdel, G. G. J. Neurosci. 13, 4114–4129 (1993).
Hübener, M., Shoham, D., Grinvald, A., and Bonhoeffer, T. In Göttinger Neurobiology Report 1996, Elsner, N. and Schnitzler, H.-U., editors, 410, (1996).
Löwel, S., Schmidt, K., Kim, D.-S., Singer, W., and Bonhoeffer, T. In Learning and Memory, Elsner, N. and Menzel, R., editors, volume 14, 98, (1995).
Spatz, W. Brain Res. 488, 376–380 (1989).
LeVay, S., Connolly, M., Houde, J., and van Essen, D. J. Neurosci. 5, 486–501 (1985).
Jones, D. G., Sluyters, R. C. V., and Murphy, K. M., J. Neurosci. 11, 3794–3808 (1991).
Kaas, J. In Comparative Neurology of the Telencephalon, Ebbeson, S., editor, 483–502. Plenum Press, NY (1980).
Gilbert, C. and Wiesel, T. J. Neurosci. 9, 2432–2442 (1989).
Malach, R., Amir, Y., Harel, M., and Grinvald, A. Proc. Natl. Acad. Sci USA 90, 10469–10473 (1993).
Fitzpatrick, D. In Cold Spring Harbour Symposia on Quantitative Biology. (1995).
Katz, L. C. and Callaway, E. M. Ann. Rev. Neurosci. 15, 31–56 (1992).
Fitzpatrick, D. Cerebral Cortex 6, 329–341 (1996).
Blasdel, G. G., Obermayer, K., and Kiorpes, L. Visual Neuroscience 12, 589–603 (1995).
Weliky, M., Kandler, K., Fitzpatrick, D., and Katz, L. C. Neuron 15, 541–552 (1995).
Weliky, M., Bosking, W. H., and Fitzpatrick, D. Nature 379, 725–728 (1996).
Wolf, F., Bauer, H.-U., Pawelzik, K., and Geisel, T. Nature 382, 306–307 (1996).
Kim, D.-S. and Bonhoeffer, T. Nature 370, 370–372 (1994).
Antonini, A. and Stryker, M. P. Science 260, 1819–1821 (1993).
Thoenen, H. Science 270, 593–598 (1995).
Wong, R., Meister, M., and Shatz, C. Neuron 11, 923–938 (1993).
Yuste, R., Nelson, D. A., Rubin, W. W., and Latz, L. C. Neuron 14, 7–17 (1995).
Kossel, A., Löwel, S., and Bolz, J. J. Neuroscience 15, 3913–3926 (1995).
Cross, M. and Hohenberg, P. Rev. Mod. Phys. 65(3), 850–1112 (1993).
Reid, R. C. and Alonso, J.-M. Nature 378, 281–284 (1995).
Ferster, D., Chung, S., and Wheat, H. S. Nature 380, 249–252 (1996).
Goodman, C. S. and Shatz, C. J. Neuron 10, 77–98 (1993).
Pettigrew, J. D. In Neuronal Plasticity, Cotman, C. W., editor, 311–330. Raven Press, NY (1978).
Hubel, D. and Wiesel, T. J. Physiol. 206, 419–436 (1970).
Cragg, B. J. Comp. Neurol. 160, 147–166 (1975).
Mitchell, D. E. and Timney, B. In Analysis of Visual Behavior, Ingle, D., Goodale, M., and Mansfield, R., editors, chapter 16, 483–523. MIT Press, Cambridge, Mass (1982).
Shaw, C., Wilkinson, M., Cynader, M., Needler, M., Aoki, C., and Hall, S. Brain Res. Bull. 16, 223–233 (1986).
Kato, N., Artola, A., and Singer, W. Dev. Brain Res. 60, 43–50 (1991).
Kirkwood, A., Lee, H.-K., and Bear, M. F. Nature 375, 328–331 (1995).
Hubel, D. H. and Wiesel, T. N. J. Neurophysiol. 26, 994–1002 (1963).
Braastad, B. and Heggelund, P. J. Neurophysiol. 53, 1158–1178 (1985).
Author information
Authors and Affiliations
Editor information
Rights and permissions
Copyright information
© 1999 Springer-Verlag
About this paper
Cite this paper
Wolf, F., Geisel, T. (1999). Pattern formation in the developing visual cortex: Topological defects, their generation, motion, and annihilation. In: Reguera, D., Vilar, J., Rubí, J. (eds) Statistical Mechanics of Biocomplexity. Lecture Notes in Physics, vol 527. Springer, Berlin, Heidelberg. https://doi.org/10.1007/BFb0105017
Download citation
DOI: https://doi.org/10.1007/BFb0105017
Published:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-66245-7
Online ISBN: 978-3-540-48486-8
eBook Packages: Springer Book Archive