Skip to main content

The treatment of time in a case-based analysis of experimental medical studies

  • Technical Papers-section 5
  • Conference paper
  • First Online:
KI-98: Advances in Artificial Intelligence (KI 1998)

Part of the book series: Lecture Notes in Computer Science ((LNAI,volume 1504))

Included in the following conference series:

  • 203 Accesses

Abstract

Case-based approaches are employed within a multitude of application areas one of which is the prediction of dynamic behaviour. Given a situation the possible development after a time span shall be determined. If only a small set of heterogenously structured cases describing observations at a variety of time points is given to start with, as it is the case when experimental medical studies shall be analysed, it becomes necessary to analyse and evaluate the temporal horizon from case to case differently, and treat time as a first class variable. This is the strategy OASES (Our Approach to Simulation based on Experimental Studies) employs. For this purpose, OASES utilises knowledge implicit in cases for matching and adaptation. Whether different time points do match in the current situation or how different time points of observation might effect the development, is decided based on cases which time is an explicit part of. Keywords: Case-Based Reasoning; Case-Based Similarity Ranking; Case-Based Adaptation; Prediction; Experimental Studies

The research was sponsored by the Forschungsschwerpunktprogramm Baden Wuerttemberg. We would like to thank the Department of Orthopaedic Research and Biomechanics at the University of Ulm for their cooperation.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. H.T. Aro and E.Y.S. Chao. Bone-healing patterns affected by loading, fracture fragment stability, fracture type, and fracture site compression. Clinical Orthopaedics and Related Research, (293): 8–17, 1993.

    Google Scholar 

  2. L. Claes, J. Reinmueller, and L. Duerselen. Experimentelle untersuchungen zum einfluss der interfragmentaeren bewegungen auf die knochenheilung. Hefte zur Unfallheilkunde, (189):53–58, 1987.

    Google Scholar 

  3. L. Claes, H.-J. Wilke, P. Augat, S. Ruebenacker, and K.J. Margevicius. Effect of dynamization on gap healing of diaphyseal fractures under external fixations. Clinical Biomechanics, 10(5):227–234, 1995.

    Article  Google Scholar 

  4. D. Damm, F.W. von Henke, A. Seitz, A.M. Uhrmacher, L. Claes, and S. Wolf. Ein fallbasiertes system f’ur die interpretation von literatur zur knochenheilung. Technical Report 98-01, Ulmer Informatik-Berichte, Universit” at Ulm, 1998.

    Google Scholar 

  5. R. Duda and P. Hart. Pattern Classification and Scene Analysis. Wiley, New York, 1973.

    MATH  Google Scholar 

  6. T.A. Einhorn. Enhancement of fracture-healing. J Bone Joint Surg Am, 77(6):940–56, 1995.

    Google Scholar 

  7. A.E. Goodship J. Kenwright. Controlled mechanical stimulation in the treatment of tibial fractures. Clin Orthop, (241):36–47, 1989.

    Google Scholar 

  8. J. Kolodner. Case-Based Reasoning. Morgan Kaufman Publishers, San Mateo, CA, 1993.

    Google Scholar 

  9. Phyllis Koton. Integrating case-based and causal reasoning. In Proceedings of the Tenth Annual Conference of the Cognitive Science Society. Montreal, 17.-19.8.1988, pages 167–173, Northvale, N.J., 1988. Erlbaum.

    Google Scholar 

  10. D.B. Leake, A. Kinley, and D. Wilson. A case study of case-based cbr. In D.B. Leake and E. Plaza, editors, Case-Based Reasoning Research and Development, Proceedings of the 2nd International Conference on Case-Based Reasoning, volume 1266 of Lecture Notes in Artificial Intelligence, pages 371–82, Berlin, 1997, Springer.

    Google Scholar 

  11. G. Nakhaeizadeh. Learning prediction of time series—a theoretical and empirical comparison of cbr with some other approaches. In S. Wess, K.-D. Althoff, and M.M. Richter, editors, Topics in Case-Based Reasoning, volume 837 of Lecture Notes in Artificial Intelligence, pages 65–76, Berlin, 1993, Springer.

    Google Scholar 

  12. A. Nebot, F.E. Cellier, and D.A. Linkens. Controlling an anaesthetic agent by means of fuzzy inductive reasoning. In Proc. QUARDET’93, IMACS Intl. Workshop on Qualitative Reasoning and Decision Technologies, Barcelona, Spain, June 1993.

    Google Scholar 

  13. M.E. O’Sullivan, J.T. Bronk, E.Y. Chao, and P.J. Kelly. Experimental study of the effect of weight bearing on fracture healing in the canine tibia. Clin Orthop, (302):273–283, 1994.

    Google Scholar 

  14. R. Schmidt, B. Heindl, B. Pollwein, and L. Gierl. Abstractions of data and time for multiparametric time course prognoses. In I. Smith and B. Faltings, editors, Advances in Case-Based Reasoning, volume 1168 of Lecture Notes in Artificial Intelligence, pages 377–391, Berlin, 1996. Springer.

    Chapter  Google Scholar 

  15. D. Shepard. A two dimensional interpolation function for irregularly-spaced data. In Proc. ACM National Conference, pages 517–524, 1968.

    Google Scholar 

  16. A.M. Uhrmacher, R.J. Frye, and F.E. Cellier. Applying fuzzy based inductive reasoning to analyze qualitatively the dynamic behavior of an ecological system. The International Journal on Artificial Intelligence in Natural Resource Management, 11(2):1–10, 1997.

    Google Scholar 

  17. D. Wettschereck, D.W. Aha, and T. Mohri. A review and comparative evaluation of feature weighting methods for lazy learning algorithms. Artificial Intelligence Review, 11:273–314, 1997.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Otthein Herzog Andreas Günter

Rights and permissions

Reprints and permissions

Copyright information

© 1998 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Seitz, A., Uhrmacher, A.M. (1998). The treatment of time in a case-based analysis of experimental medical studies. In: Herzog, O., Günter, A. (eds) KI-98: Advances in Artificial Intelligence. KI 1998. Lecture Notes in Computer Science, vol 1504. Springer, Berlin, Heidelberg . https://doi.org/10.1007/BFb0095441

Download citation

  • DOI: https://doi.org/10.1007/BFb0095441

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-65080-5

  • Online ISBN: 978-3-540-49656-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics