H+ transport by a non-electrogenic gastric ATpase as a model for acid secretion

Part of the Reviews of Physiology, Biochemistry and Pharmacology book series (REVIEWS, volume 79)


It would appear, therefore, that hog gastric mucosa contains a particularly interesting system which in many respects is compatible with a model for H+ secretion. It is quite different, at current levels of analysis, from the H+ ATPase of mitochondria. Indeed the stomach appears to have developed a unique method of developing H+ gradients. The magnitude of this gradient is such that perhaps this ATPase is only partially responsible, and that a second pump, in series with the one discussed in some detail here, is required for the complete process.


Gastric Mucosa Acid Secretion Plasma Membrane ATPase Electrogenic Pump Electrophoretic Fraction 
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Copyright information

© Springer-Verlag 1977

Authors and Affiliations

  1. 1.Laboratory of Membrane BiologyUniversity of Alabama in BirminghamBirminghamUSA

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