Intrathyroidal amines in the regulation of thyroid activity

Part of the Reviews of Physiology, Biochemistry and Pharmacology book series (volume 73)


Mast Cell Thyroid Hormone Follicle Cell Thyroid Activity Parafollicular Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Ackerman, N. B., Arons, W. L.: The effect of epinephrine and norepinephrine on the acute thyroid release of thyroid hormones. Endocrinology 62, 723–737 (1958).Google Scholar
  2. Ahn, C.S., Athans. J.C, Rosenberg, I. N.: Effects of epinephrine and of alteration in glandular blood flow upon thyroid function: studies using thyroid vein cannulation in dogs. Endocrinology 84, 501–507 (1969).Google Scholar
  3. Al Saadi, A.: Effect of normal iodine diet on the thyroid gland of iodine deficient rats: an electron microscopic study. Abstracts from the 4th meeting of the European Thyroid Association, Berne, Switzerland, 1971, abstract No. 60, p. 36.Google Scholar
  4. Aleshin, B. V., Chuprinova, S. I.: The effect of sympathetic impulses on the intrathyroidal hormonogenesis when the pituitary thyrotropic function is depressed. Probl. Endokr. (Moscow) 13, 63–67 (1967).Google Scholar
  5. Almqvist, S., Malmqvist, E., Owman, Ch., Ritzén, M., Sundler, F., Swedin, G.: Dopamine synthesis and storage, calcium-lowering activity and thyroidal properties of chicken ultimobranchial cells. Gen. comp. Endocr. 17, 512–525 (1971).Google Scholar
  6. Atack, C. V., Ericson, L. E., Melander, A.: Intracellular distribution of amines and calcitonin in the sheep thyroid gland. J. Ultrastruct. Res. 41, 484–498 (1972).Google Scholar
  7. Avioli, L. V., Shieber, W., Kipnis, D. M.: Role of glucagon and adrenergic receptors in thyrocalcitonin release in the dog. Endocrinology 88, 1337–1340 (1971).Google Scholar
  8. Bates, F. R. L., Bruce, J. B., Care, A. D.: The effect of catecholamines on calcitonin secretion in the pig. J. Endocr. 46, xi–xii (1970).Google Scholar
  9. Becker, H. D., Konturek, S. J., Reeder, D. D., Thompson, J. C: Effect of calcium and calcitonin on gastrin and gastric secretion in cats. Amer. J. Physiol. 225, 277–280 (1973).Google Scholar
  10. Becker, H. D., Reeder, D. D., Scurry, M. T., Thompson, J. C: Inhibition of gastrin release and gastric secretion by calcitonin in patients with peptic ulcer. Amer. J. Surg. 127, 71–75 (1974).Google Scholar
  11. Bell, N. H., Queener, S.: Stimulation of calcitonin synthesis and release in vitro by calcium and dibutyryl cyclic AMP. Nature (Lond.) 248, 343 (1974).Google Scholar
  12. Benditt, E. P., Wong, R. L., Arase, M., Roeper, E.: 5-Hydroxytryptamine in mast cells. Proc. Soc. exp. Biol. (N.Y.) 90, 303–304 (1955).Google Scholar
  13. Bertler, Å., Falck, B., Hillarp, N. Å., Rosengren, E., Torp, A.: Dopamine and chromaffin cells. Acta physiol. scand. 47, 251–258 (1959).Google Scholar
  14. Björkman, U., Ekholm, R., Elmqvist, L.-G., Ericson, L. E., Melander, A., Smeds, S.: Induced unidirectional transport of protein into the thyroid follicular lumen. Endocrinology 95, 1506–1517 (1974).Google Scholar
  15. Bowers, C. Y., Schally, A. V., Reynolds, G. A., Hawley, W. D.: Interactions of l-thyroxine or l-triiodothyronine and thyrotropin-releasing factor on the release and synthesis of thyrotropin from the anterior pituitary gland of mice. Endocrinology 81, 741–747 (1967).Google Scholar
  16. Brown-Grant, K., Gibson, J. G.: The effect of exogenous and endogenous adrenaline on the uptake of radio-iodine by the thyroid gland of the rabbit. J. Physiol. (Lond.) 131, 85–101 (1956).Google Scholar
  17. Brown-Grant, K., Harris, G. W., Reichlin, S.: The effect of emotional and physical stress on thyroid activity in the rabbit. J. Physiol. (Lond.) 126, 29–40 (1954).Google Scholar
  18. Brown-Grant, K., Pethes, G.: The response of the thyroid gland of the guinea-pig to stress. J. Physiol. (Lond.) 151, 40–50 (1960).Google Scholar
  19. Bussolati, G., Pearse, A. G. E.: Immunofluorescent localization of calcitonin in the “C” cells of pig and dog thyroid. J. Endocr. 37, 205–209 (1967).Google Scholar
  20. Cannon, W. B.: Studies of ductless glands by the electric method. Proc. nat. Acad. Sci. (Wash.) 2, 319–320 (1916).Google Scholar
  21. Cannon, W. B., Binger, L., Fitz, R.: Experimental hyperthyroidism. Amer. J. Physiol. 36, 363–364 (1915).Google Scholar
  22. Cannon, W. B., Catell, McK.: The secretory innervation of the thyroid. Amer. J. Physiol. 41, 58–73 (1916).Google Scholar
  23. Cannon, W. B., Fitz, R.: Further observation on overactivity of the cervical sympathetic. Amer. J. Physiol. 40, 126 (1916).Google Scholar
  24. Capen, C. C., Young, D. M.: Fine structural alterations of thyroid parafollicular cells of cows in response to experimental hypercalcemia induced by vitamin D. Amer. J. Path. 57, 365–382 (1969).Google Scholar
  25. Care, A. D., Bates, P. F. L.: The secretion of parathyroid hormone and calcitonin. Hormones 1, 364–378 (1970).Google Scholar
  26. Care, A. D., Bates, R. F. L., Bruce, J. B., Swaminathau, R., Bloom, S., Ganguli, P. C.: Stimulation of calcitonin secretion by gastro-intestinal hormones. J. Endocr. 52, 27–28 (1972).Google Scholar
  27. Care, A. D., Bates, R. F. L., Swaminathau, R., Ganguli, P. C: The role of gastrin as a calcitonin secretagogue. J. Endocr. 51, 735–744 (1971).Google Scholar
  28. Chiu, H., Lagunoff, D.: Histochemical comparison of vertebrate mast cells. Histochem. J. 4, 135–144 (1972).Google Scholar
  29. Clayton, J. A., Masuoka, D. T.: TSH-induced mobilization of serotonin from perivascular mast cells in the rat thyroid. Endocrinology 83, 263–271 (1968).Google Scholar
  30. Clayton, J. A., Szego, C. M.: Depletion of rat thyroid serotonin accompanied by increased blood flow as an acute response to thyroid-stimulating hormone. Endocrinology 80, 689–698 (1967).Google Scholar
  31. Cooper, C. W., Schwesinger, W. H., Mahgoub, A.M., Ontjes, D. A.: Thyrocalcitonin: stimulation of secretion by pentagastrin. Science 172, 1238–1240 (1971).Google Scholar
  32. Cooper, C. W., Schwesinger, W. H., Ontjes D. A., Maghoub, A. M., Munson, P. L.: Stimulation of secretion of pig thyrocalcitonin by gastrin and related hormonal peptides. Endocrinology 91, 1079–1089 (1972).Google Scholar
  33. Copp, H. D.: Calcitonin and parathyroid hormone. Ann. Rev. Pharmacol. 9, 327–344 (1969).Google Scholar
  34. Copp, H. D.: Endocrine regulation of calcium metabolism. Ann. Rev. Physiol. 32, 61–86 (1970).Google Scholar
  35. Dahlström, A., Ericson, L. E.: Monoamines in rat thyroid parafollicular cells and the effect of vitamin D2-induced degranulation. Z. Zellforsch. 128, 406–425 (1972).Google Scholar
  36. De Grandi, P. B., Kraehenbuhl, J. P., Campiche, M. A.: Ultrastructural localization of calcitonin in the parafollicular cells of pig thyriod gland with cytochrome C-labeled antibody fragments. J. Cell Biol. 50, 446–456 (1971).Google Scholar
  37. Ducommun. P., Sakiz, E., Guillemin, R.: Lability of plasma TSH levels in response to nonspecific exteroceptive stimuli. Proc. Soc. exp. Biol. (N. Y.) 121, 921–923 (1966).Google Scholar
  38. Ehrlich, P.: Beiträge zur Kenntnis der granulierten Bindegewebszellen und der eosinophilen Leukocythen. Arch. Anat. Physiol. 3, 166–169 (1879).Google Scholar
  39. Ekholm, R., Ericson, L. E.: The ultrastructure of the parafollicular cells of the thyroid gland in the rat. J. Ultrastruct. Res. 23, 378–402 (1968).Google Scholar
  40. Ekholm, R., Ericson, L. E., Lundquist, I.: Monoamines in the pancreatic islets of the mouse. Subcellular localization of 5-hydroxytryptamine by electron microscopic autoradiography. Diabetologia 7, 339–348 (1971).Google Scholar
  41. Ekholm, R., Smeds, S.: On dense bodies and droplets in the follicular cells of the guinea-pig thyroid. J. Ultrastruct. Res. 16, 71–82 (1966).Google Scholar
  42. Enerbäck, L. Cytofluorometric demonstration of a catecholamine in rat mast cells after the administration of DOPA. Histochem. J. 5, 131–142 (1972).Google Scholar
  43. Enerbäck, L., Häggendal, J.: Uptake and storage of catecholamines in mucosal mast cells of the rat. J. Histochem. Cytochem. 18, 803–811 (1970).Google Scholar
  44. Englund, N. E., Nilsson, G., Owman, Ch., Sundler, F.: Human thyroid C cells: Occurrence and amine formation studied by perfusion of surgically removed goitrous gland. J. clin. Endocr. 35, 90–96 (1972).Google Scholar
  45. Ericson, L. E.: Degranulation of the parafollicular cells of the rat thyroid by vitamin D2-induced hypercalcemia. J. Ultrastruct. Res. 24, 145–149 (1968).Google Scholar
  46. Ericson, L. E.: Subcellular localization of 5-hydroxytryptamine in the parafollicular cells of the mouse thyroid gland. An autoradiographic study. J. Ultrastruct. Res. 31, 162–177 (1970).Google Scholar
  47. Ericson, L. E.: Quantitative electron microscopic autoradiography on the mouse thyroid gland after administration of 3H-l-DOPA. Z. Zellforsch. 126, 182–192 (1972a).Google Scholar
  48. Ericson, L. E.: Formation and storage of 5-hydroxytryptamine in thyroid parafollicular cells. J. Ultrastruct. Res. 41, 467–483 (1972b).Google Scholar
  49. Ericson, L. E.: The calcitonin-producing cells of the thyroid gland. Ultrastructural aspects of the storage of monoamines and the polypeptide hormone. Thesis, Göteborg (1972c).Google Scholar
  50. Ericson, L. E., Håkanson, R., Melander, A., Owman, Ch., Sundler, F.: TSH-induced release of 5-hydroxytryptamine and histamine from rat thyroid mast cells. Endocrinology 90, 795–801 (1972).Google Scholar
  51. Ericson, L. E., Melander, A., Owman, Ch., Sundler, F.: Endocytosis of thyroglobulin and release of thyroid hormone in mice by catecholamines and 5-hydroxytryptamine. Endocrinology 87, 915–923 (1970).Google Scholar
  52. Falck, B., Larson, B., v. Mecklenburg, C., Rosengren, E., Svenaeus, K.: On the presence of a second specific cell system in mammalian thyroid gland. Acta physiol. scand. 62, 491–492 (1964b).Google Scholar
  53. Falck, B., Nystedt, T., Rosengren, E., Stenflo, J.: Dopamine and mast cells in ruminants. Acta pharmacol. toxicol. 21, 51–58 (1964 a).Google Scholar
  54. Falck, B., Owman, Ch.: 5-Hydroxytryptamine and related amines in endocrine cell systems. Advanc. Pharmacol. 6 (A), 211–231 (1968).Google Scholar
  55. Falconer, I. R.: The effect of adrenaline and noradrenaline on hormone secretion and blood flow from the thyroid vein in sheep with exteriorized thyroids. J. Physiol. (Lond.) 188, 425–434 (1967).Google Scholar
  56. Falconer, I. R., Hetzel, B. S.: Effect of emotional stress and TSH on thyroid vein hormone level in sheep with exteriorized thyroids. Endocrinology 75, 42–48 (1964).Google Scholar
  57. Fillion, G. M. B., Slorach, S. A., Uvnäs, B. The release of histamine, heparin and granule protein from rat mast cells treated with compound 48/80 in vitro. Acta physiol. scand. 78, 547–560 (1970).Google Scholar
  58. Frankel, S., Yasumura, S.: Changes in the thyroidal content of thyrocalcitonin produced by vitamin D in rats. Endocrinology 88, 267–270 (1971).Google Scholar
  59. Galton, V.A.: Thyroid hormone-catecholamine interrelationships. Endocrinology 77, 278–284 (1965).Google Scholar
  60. Gershon, M. D., Belshaw, B., Nunez, E. A.: Biochemical, histochemical and ultrastructural studies of thyroid serotonin, parafollicular and follicular cells during development in the dog. Amer. J. Anat. 132, 5–20 (1971).Google Scholar
  61. Gershon, M. D., Nunez, E. A.: Histochemical and radioautographic studies of serotonin and parafollicular cells in the thyroid gland of the prehibernating bat. Endocrinology 86, 160–166 (1970).Google Scholar
  62. Gershon, M. D., Nunez, E. A.: Subcellular storage organelles for 5-hydroxytryptamine in parafollicular cells of the thyroid gland. The effect of drugs which deplete the amine. J. Cell Biol. 56, 676–689 (1973).Google Scholar
  63. Gershon, M. D., Ross, L. L.: Location of sites of 5-hydroxytryptamine storage and metabolism by radioautography. J. Physiol. (Lond.) 186, 477–492 (1966).Google Scholar
  64. Goldman, H.: Effect of acute stress on the pituitary gland: endocrine blood flow. Endocrinology 72, 588–591 (1963).Google Scholar
  65. Guillemin, R.: The adenohypophysis and its hypothalamic control. Ann. Rev. Physiol. 44, 161–185 (1967).Google Scholar
  66. Harrison, T. S.: Adrenal medullary and thyroid relationships. Physiol. Rev. 44, 161–185.Google Scholar
  67. Harrison, T. S., Silver, D. M., Zuidema, G. D.: Thyroid and adrenal medullary function in chronic “executive” monkeys. Endocrinology 78, 685–689 (1966).Google Scholar
  68. Hays, M. T.: Effect of epinephrine on radioiodine uptake by the normal human thyroid. J. clin. Endocr. 25, 465–468 (1965).Google Scholar
  69. Håkanson, R., Melander, A., Owman, Ch., Sundler, F.: Depletion of secretory granules, calcitonin, and formaldehyde-ozone-induced fluorescence from cat thyroid C cells by vitamin D2 treatment. Histochemie 36, 89–96 (1973).Google Scholar
  70. Håkanson, R., Owman, Ch., Sundler, F.: Aromatic l-amino acid decarboxylase in calcitoninproducing cells. Biochem. Pharmacol. 20, 2187–2190 (1971).Google Scholar
  71. Hillier, A. P.: Thyroxine deiodination during cold exposure in the rat. J. Physiol. (Lond.) 197, 123–134 (1968).Google Scholar
  72. Iino, S.: Influence of the stimulation of the cervical sympathetic nerve on the mechanism of the hormonal secretion of the thyroid gland. Folia endocr. japon. 34, 933 (1959).Google Scholar
  73. Ingbar, S. H.: Thyrotoxic storm. In: The thyroid. New York: Harper & Row 1971.Google Scholar
  74. Johansson, S., Levi, L., Lindstedt, S.: Stress and the thyroid gland: A review of clinical and experimental studies, and a report of own data on experimentally induced PBI reactions in man. Reports from the Laboratory for Clinical Stress Research. 17, No. 17 (1970)Google Scholar
  75. Kalina, M., Pearse, A. G. E.: Ultrastructural localization of calcitonin in C-cells of dog thyroid; an immunocytochemical study. Histochemie 26, 1–8 (1971).Google Scholar
  76. Kameda, Y.: Light and electron microscopic alterations of the dog parafollicular cells induced by antithyroid drug. Arch. histol. japon. 36, 205–220 (1974).Google Scholar
  77. Kapitola, J., Schüllerova, M., Schreiberova, O.: Blood flow and radioiodine uptake in the thyroid gland of rats after administration and discontinuation of methylthiouracil. Acta endocr. 65, 435–441 (1970).Google Scholar
  78. Kapitola, J., Schüllerova, M., Schreiberova, O.: Blood flow and radioiodine uptake in the thyroid gland of rats after administration and discontinuation of carbimazole and perchlorate. Acta endocr. 68, 817–825 (1971).Google Scholar
  79. Kosanović, M., Ekholm, R., Strandberg, U., Smeds, S.: The effect of TSH on the acid phosphatase and thyroglobulin hydrolyzing activities in the guinea-pig thyroid. Exp. Cell Res. 52, 147–160 (1968).Google Scholar
  80. Kracht, J., Hachmeister, U., Breustedt, H.-J., Lenke, M.: Immunohistological studies on thyrocalcitonin in C-cells. Endokrinologie 52, 395–401 (1968).Google Scholar
  81. Kraus, F., Friedenthal, H.: Ueber die Wirkung der Schilddrüsenstoffe. Berl. klin. Wschr. 45, 1709–1714 (1908).Google Scholar
  82. Larson, B., Owman, Ch. Sundler, F.: Monoaminergic mechanisms in parafollicular cells of the mouse thyroid gland. Endocrinology 78, 1109–1114 (1966).Google Scholar
  83. Le Douarin, N., La Lièvre, C.: Démonstration de l'orgine neurale des cellules à calcitonine du corps ultomobranchial chez l'embryon du poulet. C.R. Acad. Sci. (Paris), Ser. D 270, 2857–2860.Google Scholar
  84. Levi, L.: Stress and distress in response to psychosocial stimuli. Acta med. scand., Suppl. 528 (1972).Google Scholar
  85. Lidz, T., Cohn, G. I.: Hyperthyroidism: Emotional factors. In: The thyroid. New York: Harper & Row 1971Google Scholar
  86. Lundquist, I.: Insulin release. Acta physiol. scand., Suppl. 372 (1971).Google Scholar
  87. Lundquist, I., Ekholm, R., Ericson, L. E.: Monoamines in the pancreatic islets of the mouse. 5-Hydroxytryptamine as an intracellular modifier of insulin secretion and the hypoglycaemic action of monoamine oxidase inhibitors. Diabetologia 7, 414–422 (1971).Google Scholar
  88. Maayan, M. L., Ingbar, S. H.: Epinephrine. Effect on uptake of iodine by dispersed cells of calf thyroid gland. Science 162, 124–125 (1968).Google Scholar
  89. Maayan, M. L., Ingbar, S. H.: Effects of epinephrine on iodine and intermediary metabolism in isolated thyroid cells. Endocrinology 87, 585–595 (1970).Google Scholar
  90. Maayan, M. L., Miller, S. L., Ingbar, S. H.: Effects of serotonin on iodide and intermediary metabolism in isolated thyroid cells. Endocrinology 88, 620–626 (1971).Google Scholar
  91. Malmqvist, E., Ericson, L. E., Almqvist, S., Ekholm, R.: Granulated cells, uptake of amine precursors, and calcium lowering activity in the ultimobranchial body of the domestic fowl. J. Ultrastruct. Res. 23, 457–461 (1968).Google Scholar
  92. McKenzie, J. M.: Does LATS cause hyperthyroidism in Grave's disease? (A review biased toward the affirmative). Metabolism 21, 883–894 (1972).Google Scholar
  93. Melander, A.: Amines and mouse thyroid activity: A thyroid-stimulating effect of 5-hydroxytryptamine and dopamine. Acta endocr. 62, 565–576 (1969).Google Scholar
  94. Melander, A.: Amines and mouse thyroid activity: Release of thyroid hormone by catecholamines and indoleamines and its inhibition by adrenergic blocking drugs. Acta endocr. 65, 371–384 (1970).Google Scholar
  95. Melander, A.: Thyroid hormone secretion. Its regulation by intrathyroidal amines. Acta physiol. scand., Suppl. 370 (1971 a).Google Scholar
  96. Melander, A.: Interactions of adrenergic blocking drugs with the in vivo release of thyroid hormone induced by thyrotropin and the long-acting thyroid stimulator. Acta endocr. 66, 151–161 (1971b).Google Scholar
  97. Melander, A., Ericson, L. E., Ljunggren, J.-G., Norberg, K.-A., Persson, B., Sundler, F., Tibblin, S., Westgren, U.: Sympathetic innervation of the normal human thyroid. J. clin. Endocr. 39, 713–718 (1974b) (October).Google Scholar
  98. Melander, A., Ericson, L. E., Sundler, F., Ingbar, S. H.: Sympathetic innervation of the mouse thyroid and its significance in thyroid hormone secretion. Endocrinology 94, 959–966 (1974a).Google Scholar
  99. Melander, A., Nilsson, E., Sundler, F.: Sympathetic activation of thyroid hormone secretion in mice. Endocrinology 90, 194–199 (1972).Google Scholar
  100. Melander, A., Owman, Ch., Sundler, F.: TSH-induced appearance and stimulation of aminecontaining mast cells in the mouse thyroid. Endocrinology 89, 528–533 (1971a).Google Scholar
  101. Melander, A., Owman, Ch., Sundler, F.: Concomitant depletion of dopamine and secretory granules from cells in the ultimobranchial gland of vitamin D2-treated chicken. Histochemie 25, 21–31 (1971b).Google Scholar
  102. Melander, A., Owman, Ch., Sundler, F.: Effect of vitamin D2 stimulation on amine stores and secretory granules in the calcitonin cells of the mouse. Histochemie 25, 32–44 (1971c).Google Scholar
  103. Melander, A., Rerup, C.: Studies on the thyroid activity in the mouse. 1. The effects of thyroxine, corticosteroids, hypophysectomy, and changes in environmental temperature. Acta endocr. 58, 202–214 (1968).Google Scholar
  104. Melander, A., Sundler, F.: Interactions between catecholamines, 5-hydroxytryptamine and TSH on the secretion of thyroid hormone. Endocrinology 90, 188–193 (1972a).Google Scholar
  105. Melander, A., Sundler, F.: Significance of thyroid mast cells in thyroid hormone secretion. Endocrinology 90, 802–807 (1972b).Google Scholar
  106. Melander, A., Sundler, F.: Appearance of amine-containing mast cells in the mouse thyroid induced by the human long-acting thyroid stimulator (LATS). Endocrinology 92, 1362–1366 (1973).Google Scholar
  107. Melander, A., Sundler, F., Ingbar, S. H.: Effect of polyphloretin phosphate on the induction of thyroid hormone secretion by various thyroid stimulators. Endocrinology 92, 1269–1273 (1973b).Google Scholar
  108. Melander, A., Sundler, F., Westgren, U.: Intrathyroidal amines and the synthesis of thyroid hormone. Endocrinology 93, 193–200 (1973a).Google Scholar
  109. Melander, A., Sundler, F., Westgren, U.: Sympathetic innervation of the thyroid: Variation with species and with age. Endocrinology 96, 102–106 (1975).Google Scholar
  110. Mowbray, J. D., Peart, W. S.: Effects of noradrenaline and adrenaline on the thyroid. J. Physiol. (Lond.) 151, 261–271 (1960).Google Scholar
  111. Nanba, H., Fujita, H.: Fine structure of the thyroid parafollicular cells in normal vitamin D and CaCl2-treated mice. Arch. histol. japon. 30, 283–293 (1969).Google Scholar
  112. Nunez, E. A., Gershon, M. D.: Synthesis and storage of serotonin by parafollicular (C) cells of the thyroid gland of active, prehibernating and hibernating bats. Endocrinology 90, 1008–1024 (1972).Google Scholar
  113. Nunez, E. A., Gershon, M.D.: Species differences in mast cells of the thyroid gland. Endocrinology 92, 152–159 (1973).Google Scholar
  114. Nunez, E.A., Gould, R.P., Hamilton, D. W., Hayward, J. S., Holt, S. J.: Seasonal changes in the fine structure of the basal granular cells of the bat thyroid. J. Cell Sci. 2, 401–410 (1967).Google Scholar
  115. Nunez, E. A., Gould, R. P., Holt, S. J.: A study of granule formation in the bat parafollicular cells. J. Cell Sci. 5, 531–539 (1969).Google Scholar
  116. Owman, Ch., Sundler, F.: Indole metabolism in thyroid C cells of the mouse: Effects of thyrocalcitonin and thiouracil. In: Calcitonin: Symposium on thyrocalcitonin and C cells. London: Heinemann 1968.Google Scholar
  117. Pearse, A. G. E.: Common cytochemical and ultrastructural characteristics of cells producing polypeptide hormones (the APUD series) and their relevance to thyroid and ultimobranchial C cells and calcitonin. Proc. roy. Soc. Med. B 170, 71–80 (1968).Google Scholar
  118. Pearse, A. G. E.: The cytochemistry and ultrastructure of polypeptide hormone-producing cells of the APUD series and the embryologic, physiologic and pathologic implications of the concept. J. Histochem. Cytochem. 17, 303–313 (1969).Google Scholar
  119. Pearse, A. G. E., Carvalheira, A. F.: Cytochemical evidence for an ultimobranchial origin of rodent thyroid C cells. Nature (Lond.) 214, 929–930 (1967).Google Scholar
  120. Pearse, A. G. E., Pollak, J. M.: Cytochemical evidence for the neural crest origin of mammalian ultimobranchial C cells. Histochemie 27, 96–102 (1971).Google Scholar
  121. Phillippo, M., Bruce, J. B., Lawrence, C. B.: The effect of adrenaline on calcitonin secretion in conscious sheep. J. Endocr. 46, xii–xiii (1970).Google Scholar
  122. Pitt-Rivers, R., Cavalieri, R. R.: Thyroid hormone biosynthesis. In: The thyroid gland. London: Butterworths 1964.Google Scholar
  123. Purves, H. D.: Control of thyroid function. In: The thyroid gland. London: Butterworths 1964.Google Scholar
  124. Reichlin, S.: Regulation of pituitary thyrotropin release. In: Thyrotropin. Springfield, Ill.: Charles C. Thomas 1963.Google Scholar
  125. Reith, A.: Exophthalmosis-enlargement of thyroid gland: Death-autopsy-affection of cervical sympathetic. Med. Times Gazette 2, 521–523 (1865).Google Scholar
  126. Rerup, C., Melander, A.: On the bioassay of thyrotropin in plasma. Acta endocr. 50, 177–194 (1965).Google Scholar
  127. Ritzén, M., Hammarström, L., Ullberg, S.: Autoradiographic distribution of 5-hydroxytryptamine and 5-hydroxytryptophan in the mouse. Biochem. Pharmacol. 14, 313–321 (1965).Google Scholar
  128. Röhlich, P., Andersson, R., Uvnäs, B.: Electron microscope observations on compound 48/80-induced degranulation in rat thyroid mast cells. Evidence for sequential exocytosis of storage granules. J. Cell Biol. 51, 465–483 (1971).Google Scholar
  129. Romeis, B.: Mikroskopische Technik. München: Oldenbourg 1948.Google Scholar
  130. Rosenberg, I. N., Bastomsky, C. H.: The thyroid. Ann. Rev. Physiol. 27, 71–106 (1965).Google Scholar
  131. Santini, F.: Le Mastzellen nella tiroide di ratto e lo loro modificazioni in rapporto ai vari stati funzionali della ghiandiola. Arch. ital. Anat. Embriol. 67, 443–458 (1962).Google Scholar
  132. Sapirstein, L. A.: Regional blood flow by fractional distribution of indicators. Amer. J. Physiol. 193, 161–168 (1958).Google Scholar
  133. Schubert, M., Hammerman, D.: Metachromasia: chemical theory and histochemical use. J. Histochem. Cytochem. 4, 159–189 (1956).Google Scholar
  134. Seljelid, R.: A study of endocytosis in thyroid follicle cells. Thesis. Stockholm: Balder AB 1966.Google Scholar
  135. Selye, H.: The mast cells. Washington, D.C.: Butterworths 1965.Google Scholar
  136. Sjoerdsma, A., Waalkes, T. P., Weissbach, H.: Serotonin and histamine in mast cells. Science 125, 1202–1204 (1957).Google Scholar
  137. Skillern, P. G.: Genetics of Graves' disease. Mayo Clin. Proc. 47, 848–849 (1972).Google Scholar
  138. Söderberg, U. Short-term reactions in the thyroid gland. Acta physiol. scand. 42, Suppl. 147 (1958).Google Scholar
  139. Söderberg, U. Temporal characteristics of thyroid activity. Physiol. Rev. 39, 777–810 (1959).Google Scholar
  140. Solomon, D. H., Chopra, I. J.: Graves' disease — 1972. Mayo Clin. Proc. 47, 803–813 (1972).Google Scholar
  141. Stein, O., Gross, J.: Metabolism of 125I in the thyroid gland studied with electron microscopic autoradiography. Endocrinology 75, 787–798 (1964).Google Scholar
  142. Sundler, F.: Histochemistry of fluorogenic amines and peptides with NH2-terminal tryptophan in polypeptide hormone-secreting cells. Thesis. Lund 1973.Google Scholar
  143. Tjälve, H.: Catechol-and indolamines in some endocrine cell systems. An autoradiographical, histochemical and radioimmunological study. Acta physiol. scand., Suppl. 360 (1971).Google Scholar
  144. Tong, W.: Thyroid hormone synthesis and release. In: The thyroid. New York: Harper & Row 1971.Google Scholar
  145. Tong, W., Kerkof, P., Chaikoff, I. L.: Iodine metabolism of dispersed thyroid cells obtained by trypsinization of sheep thyroid glands. Biochim. biophys. Acta (Amst.) 60, 1–19 (1962).Google Scholar
  146. Uvnäs, B.: The mast cell and its biogenic amines. Pharmacology and the future of man. Vol. 4. Basel: S. Karger 1973.Google Scholar
  147. Volpe, R., Edmonds, M., Lamki, L., Clarke, P. V., Row, V. V.: The pathogenesis of Graves' disease: A disorder of delayed hypersensitivity? Mayo Clin. Proc. 47, 824–834 (1972).Google Scholar
  148. Waldstein, S. S.: Thyroid-catecholamine interrelations. Ann. Rev. Med. 17, 123–132 (1966).Google Scholar
  149. Werner, S. C: Thyrotropin. Springfield, Ill.: Charles C. Thomas 1963.Google Scholar
  150. Werner, S. C: Hyperthyroidism. Pathogenesis and Etiology. In: The thyroid. New York: Harper & Row 1971.Google Scholar
  151. Wetzel, B. K., Spicer, S. S., Wollman, S. H.: Changes in fine structure and acid phosphate localization in rat thyroid cells following thyrotropin administration. J. Cell Biol. 25, 593–618 (1965).Google Scholar
  152. Wollman, S. H., Spicer, S. S., Burstone, M. S.: Localization of esterase and acid phosphatase in granules and droplets in rat thyroid epithelium. J. Cell Biol. 21, 191–202 (1964).Google Scholar
  153. Young, D. M., Capen, C. C.: The effect of low calcium diet and vitamin D on thyrocalcitonin in cows. Endocrinology 86, 1463–1466 (1970).Google Scholar
  154. Ziegler, R., Delling, G., Pfeiffer, E. F.: The secretion of calcitonin by the perfused ultimobranchial gland of the hen. In: Calcitonin 1969. London: Heinemann 1970.Google Scholar

Copyright information

© Springer-Verlag 1975

Authors and Affiliations

  1. 1.Division of Clinical Pharmacology, Department of PharmacologyUniversity of LundSweden
  2. 2.Department of AnatomyUniversity of GöteborgGöteborgSweden
  3. 3.Department of Histology, Institute of Anatomy and HistologyUniversity of LundSweden
  4. 4.Department of PharmacologyUniversity of LundSweden

Personalised recommendations