Abstract
Biological neuronal networks are subject to modifications along development. It is well known how specific mechanisms such as hebbian transformation of the synapsis contribute to the final configuration of the adult circuits. Synchronization and desynchronization of spontaneously firing cells could play a critical role in the reinforcement of the connectivity patterns. The purpose of this work is to investigate such synchronizing mechanism in the newborn hippocampus. We show that immature hippocampal CA3 and CA1 cells burst synchronously and discuss its implications in the operation of the implicated neural networks.
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References and Notes
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Current injections evoking a burst of spikes either in the first or the second neurons do not elicit any response in the other.
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© 1997 Springer-Verlag Berlin Heidelberg
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de la Prida, L.M., Sanchez-Andres, J.V. (1997). Mechanisms of synchronization in the hippocampus and its role along development. In: Mira, J., Moreno-Díaz, R., Cabestany, J. (eds) Biological and Artificial Computation: From Neuroscience to Technology. IWANN 1997. Lecture Notes in Computer Science, vol 1240. Springer, Berlin, Heidelberg. https://doi.org/10.1007/BFb0032473
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DOI: https://doi.org/10.1007/BFb0032473
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