Abstract
The facultative anaerobe Klebsiella pneumoniae converts a wide variety of sugars to 2,3-butanediol. The theoretical maximum yield of butanediol from sugar is 0.50 kg per kg. All of the sugars commonly found in hemicellulose and cellulose hydrolysates can be converted to butanediol, including glucose, xylose, arabinose, mannose, galactose, and cellobiose. In contrast with most yeast, the inducibility of the key enzyme, xylose isomerase, facilitates rapid metabolism of xylose. In this report the metabolic pathways leading from pentoses to 2,3-butanediol are reviewed. In addition, some of the key factors affecting butanediol production are discussed. These variables include temperature, pH, sugar concentration, oxygen supply, and water activity.
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Jansen, N.B., Tsao, G.T. (1983). Bioconversion of pentoses to 2,3-butanediol by Klebsiella pneumoniae . In: Pentoses and Lignin. Advances in Biochemical Engineering/Biotechnology, vol 27. Springer, Berlin, Heidelberg. https://doi.org/10.1007/BFb0009105
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DOI: https://doi.org/10.1007/BFb0009105
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