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The immobilization of whole cells

Conference paper
Part of the Advances in Biochemical Engineering book series (ABE, volume 5)

Abstract

The literature of the last three years has seen a renaissance in the use of immobilized enzyme systems made practical by the immobilization of the entire cell. Such systems have proven to have a diversity of application unattainable with isolated pure enzymes and the operation of such systems in continuous reactors has proven to be less costly than more conventional processes based on free intact cells. Thus, whole cell immobilization as a technique should be of expanding practical and academic significance in the future.

Keywords

Cell Immobilization Free Cell Serratia Marcescens Wheat Germ Agglutinin Micrococcus Luteus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Zaborsky, O.: Immobilized Enzymes, CRC Press, Cleveland (1973).Google Scholar
  2. 2.
    Newman, H. N.: Microbios 9, 247 (1974).PubMedGoogle Scholar
  3. 3.
    Zvyagintsev, D., Pertososkaya, A. F., Yakhnin, E. D., Averbach, E. I.: Mikrobiologya 40, 1024 (1971).Google Scholar
  4. 4.
    Atkinson, B., Knight, A. J.: Biotechnol. Bioeng. 17, 1245 (1975).CrossRefGoogle Scholar
  5. 5.
    Larsen, D. H., Dimmick, R. L.: J. Bac. 88, 1381 (1964).Google Scholar
  6. 6.
    Van Wezel, A. L.: In: Tissue Culture Methods and Applications. (Patterson, M. K., Kruuse Jr., P., eds.), p. 372. New York: Academic Press 1973.Google Scholar
  7. 7.
    Chibata, I., Tosa, T., Sato, T.: Applied Microbiol. 27, 878 (1974).Google Scholar
  8. 8.
    Shimizu, S., Morioka, H., Tani, Y., Ogita, K.: J. Ferment. Technol. 53, 77 (1975).Google Scholar
  9. 9.
    Martin, G. K. A., Perlman, D.: Biotechnol. Bioeng. 18, 217 (1976).CrossRefPubMedGoogle Scholar
  10. 10.
    Mosbach, K., Mosbach, R.: Acta Chem. Scand. 20, 2807 (1966).PubMedGoogle Scholar
  11. 11.
    Updike, S. M., Harris, D. R., Shrago, E.: Nature (London) 224, 1122 (1969).PubMedGoogle Scholar
  12. 12.
    Mosbach, K., Larsson, P. O.: Biotechnol. Bioeng. 12, 19 (1970).CrossRefPubMedGoogle Scholar
  13. 13.
    Franks, N. E.: Biochem. Biophys. Acta 252, 246 (1971).PubMedGoogle Scholar
  14. 14.
    Franks, N. E.: In: Enzyme Engineering (Wingard Jr., L. B., ed.), p. 327. New York: Wiley Interscience 1972. (Biotechnol. Bioeng., Symp. No. 3).Google Scholar
  15. 15.
    Yamamoto, K., Sato, T., Tosa, T., Chibata, I.: Biotechnol. Bioeng. 16, 1601 (1974).CrossRefPubMedGoogle Scholar
  16. 16.
    Yamamoto, K., Sato, T., Tosa, T., Chibata, I.: Biotechnol. Bioeng. 16, 1589 (1974).CrossRefPubMedGoogle Scholar
  17. 17.
    Tosa, T., Sato, T., Mori, T., Chibata, I.: Applied Microbiol. 27, 886 (1974).Google Scholar
  18. 18.
    Sato, T., Mori, T., Tosa, T., Chibata, I., Furui, M., Yamashita, K., Sumi, A.: Biotechnol. Bioeng. 17, 1797 (1975).CrossRefPubMedGoogle Scholar
  19. 19.
    Saif, S., Tani, Y., Ogata, K.: J. Ferment. Technol. 53, 380 (1975).Google Scholar
  20. 20.
    Slowinski, W., Cham, S. E.: Biotechnol. Bioeng. 15, 973 (1973).CrossRefPubMedGoogle Scholar
  21. 21.
    Vieth, W. R., Wang, S. S., Saini, R.: Biotechnol Bioeng. 15, 565 (1973).CrossRefPubMedGoogle Scholar
  22. 22.
    Venkatasubramanian, K., Saini, R., Vieth, W. R.: J. Ferment. Technol. 52, 268 (1974).Google Scholar
  23. 23.
    Kennedy, J. F., Barker, S. A., Humphreys, J. D.: Nature (London) 261, 242 (1976).CrossRefPubMedGoogle Scholar
  24. 24.
    Toda, K., Shoda, M.: Biotechnol. Bioeng. 17, 481 (1975).CrossRefGoogle Scholar
  25. 25.
    Toda, K.: Biotechnol. Bioeng. 17, 1729 (1975).CrossRefGoogle Scholar
  26. 26.
    Mohan, R. R., Li, N. N.: Biotechnol. Bioeng. 17, 1137 (1975).CrossRefPubMedGoogle Scholar
  27. 27.
    Mohan, R. R., Li, N. N.: Biotechnol. Bioeng. 16, 513 (1974).CrossRefPubMedGoogle Scholar
  28. 28.
    Leuschner, F.: German Pat. 1227855 (Cl. C12d).Google Scholar
  29. 29.
    Rotman, B.: Bac. Rev's. 24, (1960).Google Scholar
  30. 30.
    Zvyagintsev, D. G.: Mikrobiologiya 31, 339 (1971).Google Scholar
  31. 31.
    Daniels, S. L., Kempe, L. L.: In: Chemical Engineering in Medicine and Biology (Herschey, D., ed.), p. 391. New York: Plenum Press 1967.Google Scholar
  32. 32.
    Zvyagintsev, D. G., Gusev, V. S.: Mikrobiologiya 40, 139 (1971).Google Scholar
  33. 33.
    Bonomi, A., Fredrickson, A. G.: Biotechnol. Bioeng. 18, 239 (1976).CrossRefPubMedGoogle Scholar
  34. 34.
    Van den Ende, P.: Science 181, 562 (1973).Google Scholar
  35. 35.
    Helmstetter, C. E.: J. Mol. Biol. 24, 417 (1967).CrossRefGoogle Scholar
  36. 36.
    Helmstetter, C. E., Cooper, S.: J. Mol. Biol. 31, 507 (1968).CrossRefPubMedGoogle Scholar
  37. 37.
    Hattori, T., Furusaka, C.: Biochem. (Tokyo) 50, 312 (1961).Google Scholar
  38. 38.
    Hattori, T., Furusaka, C.: Biochem. (Tokyo) 48, 831 (1960).Google Scholar
  39. 39.
    Hattori, R., Hattori, T., Furusaka, C.: J. Gen. Appl. Microbiol. 18, 271 (1972).Google Scholar
  40. 40.
    Hattori, R., Hattori, T., Furusaka, C.: J. Gen. Appl. Microbiol. 18, 285 (1972).Google Scholar
  41. 41.
    Hattori, R.: J. Gen. Appl. Microbiol. 18, 319 (1972).Google Scholar
  42. 42.
    Johnson, D. E., Ciegler, A.: Arch. Biochem. and Biophys. 130, 384 (1969).CrossRefGoogle Scholar
  43. 43.
    Cautrecasas, P.: Proc. Nat. Acad. Sci., U.S. 63, 450 (1969).Google Scholar
  44. 44.
    Cautrecasas, P.: In: Biochemical Aspects of Reactions on Solid Support (Stark, G. R., ed.), p. 79. New York: Plenum Press 1971.Google Scholar
  45. 45.
    Moskowitz, G. J.: U.S. Patent 3843442 (1974).Google Scholar
  46. 46.
    Lee, C. K., Long, M. E.: U.S. Patent 3821086 (1974).Google Scholar
  47. 47.
    Zabriskie, D., Ollis, D. F., Burger, M. M.: Biotechnol. Bioeng. 15, 981 (1973).CrossRefGoogle Scholar
  48. 48.
    Rutishauser, U., Sachs, L.: J. Cell Biol. 65, 247 (1975).CrossRefPubMedGoogle Scholar
  49. 49.
    Kinzel, V., Kubler, D., Richards, J., Stohr, M.: Science 192, 487 (1976).PubMedGoogle Scholar
  50. 50.
    Wigzell, H., Anderson, B.: J. Exp. Med. 129, 23 (1969).CrossRefPubMedGoogle Scholar
  51. 51.
    Evans, W. H., Mage, M. G., Peterson, E. A.: J. Immunol. 102, 899 (1969).PubMedGoogle Scholar
  52. 52.
    Truffi-Bachi, P., Wofsy, L.: Proc. Nat. Acad. Sci., U.S. 66, 685 (1970).Google Scholar
  53. 53.
    Dazzo, F. D., Hubell, P. H.: Applied Microbiol. 30, 1017 (1975).Google Scholar
  54. 54.
    Beveridge, T., Murray, R. G. E.: Private Communication.Google Scholar
  55. 55.
    Chipley, J. R.: Microbios 10, 115 (1974).PubMedGoogle Scholar
  56. 56.
    Jack, T. R., Zajic, J. E.: Biotechnol. Bioeng., in press.Google Scholar

Copyright information

© Springer-Verlag 1977

Authors and Affiliations

  1. 1.Scarborough CollegeUniversity of TorontoWest Hill
  2. 2.Faculty of Engineering ScienceThe University of Western OntarioLondon

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