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The principle and technology of hydrogen peroxide based biosensors

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Measurement and Control

Part of the book series: Advances in Biochemical Engineering/Biotechnology ((ABE,volume 50))

Abstract

Oxidases can be used with a hydrogen peroxide electrode to construct amperometric biosensors for determination of various analytes, including substrates, cofactors, prosthetic groups, inhibitors, activators, enzyme activities, as well as antigens/antibodies. This chapter reviews the principle and technology of hydrogen peroxide-based biosensors and the techniques for enzyme immobilization. Methods for alleviation of interference by electroactive species are cited with an emphasis on mediator technology. The present state of applications and development trends of this technology are also presented and discussed.

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Authors and Affiliations

  1. Biotechnology Research Institute, National Research Council Canada, H4P 2R2, Montreal, Quebec, Canada

    John H. T. Luong & A. -L. Nguyen

  2. Department of Chemistry, University of New Orleans, New Orleans, Louisiana, USA

    George G. Guilbault

Authors
  1. John H. T. Luong
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  2. A. -L. Nguyen
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  3. George G. Guilbault
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© 1993 Springer-Verlag

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Luong, J.H.T., Nguyen, A.L., Guilbault, G.G. (1993). The principle and technology of hydrogen peroxide based biosensors. In: Measurement and Control. Advances in Biochemical Engineering/Biotechnology, vol 50. Springer, Berlin, Heidelberg. https://doi.org/10.1007/BFb0007388

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  • DOI: https://doi.org/10.1007/BFb0007388

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-56536-9

  • Online ISBN: 978-3-540-47587-3

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