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Molybdenum-containing enzymes

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Structure and Bonding, Volume 11

Part of the book series: Structure and Bonding ((STRUCTURE,volume 11))

Abstract

So little is known about molybdenum enzymes other than milk xanthine oxidase that there is little to be said by way of general conclusions. In all cases where there is direct evidence (except possibly for xanthine dehydrogenase from Micrococcus lactilyticus) it seems that molybdenum in the enzymes does have a redox function in catalysis. For the xanthine oxidases and dehydrogenases and for aldehyde oxidase, the metal is concerned in interaction of the enzymes with reducing substrates. However, for nitrate reductase it is apparently in interaction with the oxidizing substrate that the metal is involved. In nitrogenase the role of molybdenum is still quite uncertain.

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Authors and Affiliations

  1. School of Molecular Sciences, University of Sussex, BN19 QJ, Brighton, Great Britain

    R. C. Bray

  2. Biochemistry Department, Monash University, 3168, Clayton, Victoria, Australia

    J. C. Swann

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  1. R. C. Bray
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  2. J. C. Swann
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Bray, R.C., Swann, J.C. (1972). Molybdenum-containing enzymes. In: Structure and Bonding, Volume 11. Structure and Bonding, vol 11. Springer, Berlin, Heidelberg. https://doi.org/10.1007/BFb0002461

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  • DOI: https://doi.org/10.1007/BFb0002461

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