Abstract
Multiple Sclerosis (MS) is an inflammatory demyelination of the central nervous system that progresses to complete or incomplete recovery of neurological dysfunction. Accurately identifying the degree of damage to the brain matter is critical for prognosis. Progression of MS must be closely monitored requiring regular assessment of symptoms through diagnostic methods like magnetic resonance imaging (MRI). This process is quite taxing and time-consuming to be done manually. This paper presents a methodology to perform automatic segmentation of multiple sclerosis via a combination approach of an unsupervised autoencoder and a pre-trained classifier for lesion detection followed by segmentation. The presented approach investigates the usability of an autoencoder for classification and segmentation. The novelty lies in reducing the reliance of the model on the availability of labeled data. This is a prevalent issue in the field of research for MS. The proposed approach has been evaluated on the FLAIR MRI images obtained from the members of Ozal University Medical Faculty in 2021 and is able to deliver good results.
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References
Sadeghibakhi M, Pourreza H, Mahyar H (2022) Multiple sclerosis lesions segmentation using attention-based CNNs in FLAIR images. IEEE J Transl Eng Health Med 10:1–11
Yoo Y, Brosch T, Traboulsee A, Li DKB, Tam R (2014) Deep learning of image features from unlabeled data for multiple sclerosis lesion segmentation. In: Wu G, Zhang D, Zhou L (eds) Machine learning in medical imaging. MLMI 2014. Lecture notes in computer science, vol 8679. Springer, Cham
Jain S, Rajpal N, Yadav J (2022) Supervised and unsupervised machine learning techniques for multiple sclerosis identification: a performance comparative analysis. https://doi.org/10.1007/978-981-16-3346-1-30
Alrabai A, Echtioui A, Hamida A (2022) Multiple sclerosis segmentation using deep learning models: comparative study. https://doi.org/10.1109/ATSIP55956.2022.9805983
McKinley R, Wepfer R, Aschwanden F et al (2021) Simultaneous lesion and brain segmentation in multiple sclerosis using deep neural networks. Sci Rep 11:1087
Rakić M, Vercruyssen S, Van Eyndhoven S, de la Rosa E, Jain S, Van Huffel S, Maes F, Smeets D, Sima DM (2021) icobrain ms 5.1: Combining unsupervised and supervised approaches for improving the detection of multiple sclerosis lesions. Neuroimage Clin 31:102707
Ansari SU, Javed K, Qaisar SM, Jillani R, Haider U (2021) Multiple sclerosis lesion segmentation in brain MRI using inception modules embedded in a convolutional neural network. J Healthc Eng 2021
Gabr RE, Coronado I, Robinson M et al (2020) Brain and lesion segmentation in multiple sclerosis using fully convolutional neural networks: a large-scale study. Multiple Sclerosis J
Alex V, Vaidhya K, Thirunavukkarasu S, Kesavadas C, Krishnamurthi G (2017) Semisupervised learning using denoising autoencoders for brain lesion detection and segmentation. J Med Imaging (Bellingham). 4(4):041311
La Rosa F, Beck ES, Maranzano J, Todea RA, van Gelderen P, de Zwart JA, Luciano NJ, Duyn JH, Thiran JP, Granziera C et al (2022) Multiple sclerosis cortical lesion detection with deep learning at ultra-high-field MRI. NMR Biomed 35:e4730
Joshi A, Sharma KK (2021) Hybrid topology of graph convolution and autoencoder deep network for multiple sclerosis lesion segmentation. In: 2021 international conference on artificial intelligence and smart systems (ICAIS), Coimbatore, India, 2021, pp 1529–1534. https://doi.org/10.1109/ICAIS50930.2021.9395914
Eshaghi A, Young AL, Wijeratne PA, Prados F, Arnold DL, Narayanan S, Guttmann CRG, Barkhof F, Alexander DC, Thompson AJ et al (2021) Identifying multiple sclerosis subtypes using unsupervised machine learning and MRI data. Nat Commun 12:2078
Merzoug A, Benamrane N, Taleb-Ahmed A (2021) Lesions detection of multiple sclerosis in 3D brain MR images by using artificial immune systems and support vector machines. Int J Cogn Inform Nat Intell 15:97–110
Garcia-Martin E, Ortiz M, Boquete L, Sánchez-Morla EM, Barea R, Cavaliere C, Vilades E, Orduna E, Rodrigo MJ (2021) Early diagnosis of multiple sclerosis by OCT analysis using Cohen’s d method and a neural network as classifier. Comput Biol Med 129:104165
Bonanno L, Mammone N, De Salvo S, Bramanti A, Rifici C, Sessa E, Bramanti P, Marino S, Ciurleo R (2021) Multiple sclerosis lesions detection by a hybrid watershed-clustering algorithm. Clin Imaging 72:162–167
Gaj S, Ontaneda D, Nakamura K (2021) Automatic segmentation of gadolinium-enhancing lesions in multiple sclerosis using deep learning from clinical MRI. PLoS One 16(9):e0255939
Rezaee A, Rezaee K, Haddadnia J, Gorji HT (2020) Supervised meta-heuristic extreme learning machine for multiple sclerosis detection based on multiple feature descriptors in MR images. SN Appl Sci 2:866
Valverde S, Salem M, Cabezas M et al (2019) One-shot domain adaptation in multiple sclerosis lesion segmentation using convolutional neural networks. NeuroImage Clin 21:101638. pmid:30555005
Baur C, Denner S, Wiestler B, Navab N, Albarqouni S (2021) Autoencoders for unsupervised anomaly segmentation in brain MR images: a comparative study. Med Image Anal 69:101952. ISSN 1361-8415. Article ID 4138137, 10 p
Shmueli OZ, Solomon C, Ben-Eliezer N, Greenspan H (2022) Deep learning based multiple sclerosis lesion detection utilizing synthetic data generation and soft attention mechanism. In: Proceedings of the medical imaging 2022: computer-aided diagnosis, San Diego, CA, USA, 20 February–28 March 2022, vol 12033, p 120330R
Macin G, Tasci B, Tasci I, Faust O, Barua PD, Dogan S, Tuncer T, Tan R-S, Acharya UR (2022) An accurate multiple sclerosis detection model based on exemplar multiple parameters local phase quantization: ExMPLPQ. Appl Sci 12:4920
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Rajangam, V., Nagarajan, S., Farheen, M.M., Yayavaram, A., Nasheeda, V.P. (2024). Segmentation of Multiple Sclerosis Using Autoencoder and Classifier. In: Asirvatham, D., Gonzalez-Longatt, F.M., Falkowski-Gilski, P., Kanthavel, R. (eds) Evolutionary Artificial Intelligence. ICEASSM 2017. Algorithms for Intelligent Systems. Springer, Singapore. https://doi.org/10.1007/978-981-99-8438-1_9
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