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Advances in Water Pollution Monitoring and Control pp 79–84Cite as

Study of Synthesis and Biological Importance of 1,4-Dihydropyridines Derivatives

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Abstract

1,4-Dihydropyridines (1,4-DHPs) are very important heterocyclic structures from which a large number of compounds are known in the field of drugs and pharmaceuticals. Interest in 1,4-dihydropyridines is mainly due to nicotinamide adenine dinucleotide (NADH), a coenzyme, with unique ability to reduce various functional groups in biological systems. They are also known for resistance reversal properties and antitubercular activities. The present study involves the reaction of three components like an aldehyde, enamine, and di keto compounds to synthesize 1,4-dihydropyridines in good yields by using green chemistry idea that is the use of an eco-friendly solvent and a catalyst TBAHS.

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Author information

Authors and Affiliations

  1. Department of Chemistry, MKP P.G. College, Dehradun, India

    Neetu Tripathi

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  1. Neetu Tripathi
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Correspondence to Neetu Tripathi .

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Editors and Affiliations

  1. Department of Health Safety, Environment and Civil Engineering, University of Petroleum and Energy Studies, Dehradun, Uttarakhand, India

    Nihal Anwar Siddiqui

  2. Department of Health Safety, Environment and Civil Engineering, University of Petroleum and Energy Studies, Dehradun, Uttarakhand, India

    S. M. Tauseef

  3. Uttarakhand State Council for Science and Technology (UCOST), Dehradun, Uttarakhand, India

    Rajendra Dobhal

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Tripathi, N. (2020). Study of Synthesis and Biological Importance of 1,4-Dihydropyridines Derivatives. In: Siddiqui, N., Tauseef, S., Dobhal, R. (eds) Advances in Water Pollution Monitoring and Control. Springer Transactions in Civil and Environmental Engineering. Springer, Singapore. https://doi.org/10.1007/978-981-32-9956-6_9

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  • DOI: https://doi.org/10.1007/978-981-32-9956-6_9

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-32-9955-9

  • Online ISBN: 978-981-32-9956-6

  • eBook Packages: EngineeringEngineering (R0)

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