Abstract
This chapter specifically reviews studies that have been done with disulfiram in head on comparisons with other agents used in the long-term management of alcohol dependence. This chapter also analyses the potential combinations of pharmacotherapy with disulfiram which would supplement, synergize and even enhance the effect of disulfiram therapy. Various drugs used in the pharmacotherapy of alcohol dependence are analyzed in the context of their use with disulfiram.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
De Sousa A, De Sousa A. An open randomized study comparing disulfiram and acamprosate in the treatment of alcohol dependence. Alcohol Alcohol. 2005;40(6):545–8.
De Sousa A, De Sousa A. A one-year pragmatic trial of naltrexone vs disulfiram in the treatment of alcohol dependence. Alcohol Alcohol. 2004;39(6):528–31.
De Sousa AA, De Sousa J, Kapoor H. An open randomized trial comparing disulfiram and topiramate in the treatment of alcohol dependence. J Subs Abuse Treat. 2008;34(4):460–3.
Diehl A, Ulmer L, Mutschler J, Herre H, Krumm B, Croissant B, Mann K, Kiefer F. Why is disulfiram superior to acamprosate in the routine clinical setting? A retrospective long-term study in 353 alcohol-dependent patients. Alcohol Alcohol. 2010;45(3):271–7.
Laaksonen E, Koski-Jännes A, Salaspuro M, Ahtinen H, Alho H. A randomized, multicentre, open-label, comparative trial of disulfiram, naltrexone and acamprosate in the treatment of alcohol dependence. Alcohol Alcohol. 2007;43(1):53–61.
Pettinati HM, Kampman KM, Lynch KG, Xie H, Dackis C, Rabinowitz AR, Charles PO. A double blind, placebo-controlled trial that combines disulfiram and naltrexone for treating co-occurring cocaine and alcohol dependence. Addict Behav. 2008;33(5):651–67.
Petrakis IL, Poling J, Levinson C, Nich C, Carroll K, Rounsaville B, VA New England VISN I MIRECC Study Group. Naltrexone and disulfiram in patients with alcohol dependence and comorbid psychiatric disorders. Biol Psychiatry. 2005;57(10):1128–37.
Kranzler HR, Van Kirk J. Efficacy of naltrexone and acamprosate for alcoholism treatment: a meta-analysis. Alcohol Clin Exp Res. 2001;25(9):1335–41.
O’Brien CP, Volpicelli LA, Volpicelli JR. Naltrexone in the treatment of alcoholism: a clinical review. Alcohol. 1996;13(1):35–9.
Krystal JH, Cramer JA, Krol WF, Kirk GF, Rosenheck RA. Naltrexone in the treatment of alcohol dependence. N Engl J Med. 2001;345(24):1734–9.
Savas MC, Güllü İH. Disulfiram–ethanol test reaction: significance of supervision. Ann Pharmacother. 1997;31(3):374–5.
Brewer C, Meyers RJ, Johnsen J. Does disulfiram help to prevent relapse in alcohol abuse? CNS Drugs. 2000;14(5):329–41.
Preston KL, Silverman K, Umbricht A, DeJesus A, Montoya ID, Schuster CR. Improvement in naltrexone treatment compliance with contingency management. Drug Alcohol Depend. 1999;54(2):127–35.
Poulsen HE, Loft S, Andersen JR, Andersen M. Disulfiram therapy–adverse drug reactions and interactions. Acta Psychiatr Scand. 1992;86(S369):59–66.
Wilson A. Disulfiram implantation in alcoholism treatment. A review. J Stud Alcohol. 1975;36(5):555–65.
Lobmaier PP, Kunøe N, Gossop M, Waal H. Naltrexone depot formulations for opioid and alcohol dependence: a systematic review. CNS Neurosci Ther. 2011;17(6):629–36.
Carmen B, Angeles M, Ana M, MarÃa AJ. Efficacy and safety of naltrexone and acamprosate in the treatment of alcohol dependence: a systematic review. Addiction. 2004;99(7):811–28.
Mason BJ. Treatment of alcohol-dependent outpatients with acamprosate: a clinical review. J Clin Psychiatry. 2001;62:42–8.
Plosker GL. Acamprosate: a review of its use in alcohol dependence. Drugs. 2015;75(11):1255–68.
Kenna GA, Lomastro TL, Schiesl A, Leggio L, Swift RM. Review of topiramate: an antiepileptic for the treatment of alcohol dependence. Curr Drug Abuse Rev. 2009;2(2):135–42.
De Sousa A. The role of topiramate and other anticonvulsants in the treatment of alcohol dependence: a clinical review. CNS Neurol Disord Drug Targets. 2010;9(1):45–9.
Guglielmo R, Martinotti G, Quatrale M, Ioime L, Kadilli I, Di Nicola M, Janiri L. Topiramate in alcohol use disorders: review and update. CNS Drugs. 2015;29(5):383–95.
Olmsted CL, Kockler DR. Topiramate for alcohol dependence. Ann Pharmacother. 2008;42(10):1475–80.
Lamb EJ, Stevens PE, Nashef L. Topiramate increases biochemical risk of nephrolithiasis. Ann Clin Biochem. 2004;41(2):166–9.
Volkow ND, Wang GJ, Fowler JS, Tomasi D, Telang F. Addiction: beyond dopamine reward circuitry. Proc Natl Acad Sci U S A. 2011;108(37):15037–42.
Gass JT, Olive MF. Glutamatergic substrates of drug addiction and alcoholism. Biochem Pharmacol. 2008;75(1):218–65.
Cruz HG, Ivanova T, Lunn ML, Stoffel M, Slesinger PA, Lüscher C. Bi-directional effects of GABA B receptor agonists on the mesolimbic dopamine system. Nat Neurosci. 2004;7(2):153–9.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer Nature Singapore Pte Ltd.
About this chapter
Cite this chapter
De Sousa, A. (2019). Disulfiram in Comparison and Combination with Other Agents in the Management of Alcohol Dependence. In: Disulfiram. Springer, Singapore. https://doi.org/10.1007/978-981-32-9876-7_5
Download citation
DOI: https://doi.org/10.1007/978-981-32-9876-7_5
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-32-9875-0
Online ISBN: 978-981-32-9876-7
eBook Packages: Behavioral Science and PsychologyBehavioral Science and Psychology (R0)