Abstract
Gastric adenoma is a benign epithelial neoplastic tumor with a glandular organization. It is characterized by localized proliferation of adenomatous epithelium with tubular and/or papillary structures [1, 2]. Gastric adenoma is regarded as a precancerous lesion and divided into low-grade adenoma (LGA, corresponding to category 3 in the Vienna classification) and high-grade adenoma (HGA, category 4.1) [3]. The risk of progression to gastric cancer increases with the histological severity, and the risk of progression from LGA to gastric cancer has been reported to be relatively low (3–9%) [4, 5].
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Goldstein NS, Lewin KJ. Gastric epithelial dysplasia and adenoma: historical review and histological criteria for grading. Hum Pathol. 1997;28:127–33.
Ming SC. Cellular and molecular pathology of gastric carcinoma and precursor lesions: a critical review. Gastric Cancer. 1998;1:31–50.
Schlemper RJ, Riddell RH, Kato Y, et al. The Vienna classification of gastrointestinal epithelial neoplasia. Gut. 2000;47:251–5.
Rugge M, Cassaro M, Di Mario F, et al. The long term outcome of gastric non-invasive neoplasia. Gut. 2003;52:1111–6.
Yamada H, Ikegami M, Shimoda T, et al. Long-term follow-up study of gastric adenoma/dysplasia. Endoscopy. 2004;36:390–6.
Dixon MF. Gastrointestinal epithelial neoplasia: Vienna revisited. Gut. 2002;51:130–1.
Kim YJ, Park JC, Kim JH, et al. Histological diagnosis based on forceps biopsy is not adequate for determining endoscopic treatment of gastric adenomatous lesions. Endoscopy. 2010;42:620–6.
Jung MK, Jeon SW, Park SY, et al. Endoscopic characteristics of gastric adenomas suggesting carcinomatous transformation. Surg Endosc. 2008;22:2705–11.
Yoon WJ, Lee DH, Jung YJ, et al. Histologic characteristics of gastric polyps in Korea: emphasis on discrepancy between endoscopic forceps biopsy and endoscopic mucosal resection specimen. World J Gastroenterol. 2006;12:4029–32.
Muehldorfer SM, Stolte M, Martus P, et al. Diagnostic accuracy of forceps biopsy versus polypectomy for gastric polyps: a prospective multicenter study. Gut. 2002;50:465–70.
Cho SJ, Choi IJ, Kim CG, et al. Risk of high-grade dysplasia or carcinoma in gastric biopsy-proven low-grade dysplasia: an analysis using the Vienna classification. Endoscopy. 2011;43:465–71.
Park DI, Rhee PL, Kim JE, et al. Risk factors suggesting malignant transformation of gastric adenoma: univariate and multivariate analysis. Endoscopy. 2001;33:501–6.
Kasuga A, Yamamoto Y, Fujisaki J, et al. Clinical characterization of gastric lesions initially diagnosed as low-grade adenomas on forceps biopsy. Dig Endosc. 2012;24:331–8.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2020 Springer Nature Singapore Pte Ltd.
About this chapter
Cite this chapter
Hatamori, H., Horiuchi, Y. (2020). Gastric Adenoma. In: Fujisaki, J. (eds) Endoscopic Treatment Strategy for Upper GI Tract Neoplasms. Springer, Singapore. https://doi.org/10.1007/978-981-32-9737-1_5
Download citation
DOI: https://doi.org/10.1007/978-981-32-9737-1_5
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-32-9736-4
Online ISBN: 978-981-32-9737-1
eBook Packages: MedicineMedicine (R0)