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Application of UPT-POCT in Detection of Drugs

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Principles and Applications of Up-converting Phosphor Technology
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Abstract

Drugs are chemicals, anesthetics and stimulants with the addiction, including morphine, methamphetamine, tetrahydrocannabinol, ketamine, and methcathinone, etc. Due to the global expanding drug markets and drug driving problems, rapid screening detection has been performed for many countries. The detection windows of different test samples are different, such as urine, saliva, and hair. UPT-LF is of high safety, stability for preservation of evidence, accuracy with low false positive rate, portability, easily operating, and it has been widely used for detection of drugs from urine, saliva and hair samples in preliminary screening test for drug abuse. The commercial UPT-POCT reagents have been applied for detection of ketamine, methamphetamine, morphine, tetrahydrocannabinol, and carbamazepine, while the first three test reagents have obtained registration certification of the CFDA Class III medical device.

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References

  • Fabritius M, Chtioui H, Battistella G, Annoni JM, Dao K, Favrat B, Fornari E, Lauer E, Maeder P, Giroud C. Comparison of cannabinoid concentrations in oral fluid and whole blood between occasional and regular cannabis smokers prior to and after smoking a cannabis joint. Anal Bioanal Chem. 2013;405(30):9791–9803.

    Article  CAS  Google Scholar 

  • Hu Q, Wei Q, Zhang P, Li S, Xue L, Yang R, Wang C, Zhou L. An up-converting phosphor technology-based lateral flow assay for point-of-collection detection of morphine and methamphetamine in saliva. Anal. 2018;143(19):4646–4654.

    Article  CAS  Google Scholar 

  • Isbell TA, Strickland EC, Hitchcock J, McIntire G, Colyer CL. Capillary electrophoresis-mass spectrometry determination of morphine and its isobaric glucuronide metabolites. J Chromatogr B Analyt Technol Biomed Life Sci. 2015;980:65–71.

    Article  CAS  Google Scholar 

  • Kuwayama K, Tsujikawa K, Miyaguchi H, Kanamori T, Iwata YT, Inoue H. Rapid, simple, and highly sensitive analysis of drugs in biological samples using thin-layer chromatography coupled with matrix-assisted laser desorption/ionization mass spectrometry. Anal Bioanal Chem. 2012;402(3):1257–1267.

    Article  CAS  Google Scholar 

  • Mikuma T, Iwata YT, Miyaguchi H, Kuwayama K, Tsujikawa K, Kanamori T, Inoue H. The use of a sulfonated capillary on chiral capillary electrophoresis/mass spectrometry of amphetamine-type stimulants for methamphetamine impurity profiling. Forensic Sci Int. 2015;249:59–65.

    Article  CAS  Google Scholar 

  • Rodrigues WC, Wang G, Moore C, Agrawal A, Vincent MJ, Soares JR. Development and validation of ELISA and GC-MS procedures for the quantification of dextromethorphan and its main metabolite dextrorphan in urine and oral fluid. J Anal Toxicol. 2008;32(3):220–226.

    Article  CAS  Google Scholar 

  • Sarris G, Borg D, Liao S, Stripp R. Validation of an EMIT(R) screening method to detect 6-acetylmorphine in oral fluid. J Anal Toxicol. 2014;38(8):605–609.

    Article  CAS  Google Scholar 

  • Shen M, Chen H, Xiang P. Determination of opiates in human fingernail—comparison to hair. J Chromatogr B, Anal Technol Biomed Life Sci 2014;967(undefined):84–89.

    Article  CAS  Google Scholar 

  • Teerinen T, Lappalainen T, Erho T. A paper-based lateral flow assay for morphine. Anal Bioanal Chem. 2014;406(24):5955–5965.

    Article  CAS  Google Scholar 

  • Verstraete AKA, Jantos R, Skopp G, Gjerde H, Vindenes V et al. Driving under the influence of drugs, Alcohol and medicines (DRUID): per se limits—methods of defining cut-off values for zero tolerance. 2011, 2011. Accessed 20 July 2014.

    Google Scholar 

  • Xiang X, Wang X, Jiang H, Chu C, Hao W. Drugs and driving in China: status and challenge. Int J Drug Policy. 2016;31:203–204.

    Article  Google Scholar 

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Correspondence to Pingping Zhang .

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Li, Y., Zhang, Y., Zhang, P. (2019). Application of UPT-POCT in Detection of Drugs. In: Yang, R. (eds) Principles and Applications of Up-converting Phosphor Technology. Springer, Singapore. https://doi.org/10.1007/978-981-32-9279-6_15

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