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Results-III. SIRT6 Is an Acetylated Protein and a NAD+-Dependent Self-deacetylase

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SIRT6 Activities in DNA Damage Repair and Premature Aging

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Abstract

This chapter establishes p300 and MOF-mediated acetylation as a novel post-translational modification of SIRT6, with implications in DNA damage responses. It further illustrates the self-deacetylation function of SIRT6 in the presence of NAD+.

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Correspondence to Shrestha Ghosh .

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Ghosh, S. (2019). Results-III. SIRT6 Is an Acetylated Protein and a NAD+-Dependent Self-deacetylase. In: SIRT6 Activities in DNA Damage Repair and Premature Aging. Springer Theses. Springer, Singapore. https://doi.org/10.1007/978-981-32-9267-3_5

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