Skip to main content

Future Directions of Research on Indoor Environment, Indoor Air Quality (IAQ), and Health

  • Chapter
  • First Online:
Indoor Environmental Quality and Health Risk toward Healthier Environment for All

Abstract

The impact of the indoor environment on human health will continue to be an important topic in the future. Large prospective studies and intervention studies are needed in different indoor environments, including homes, schools, day care centers, offices, and hospitals. More epidemiological studies using biomarkers of health effects are needed. There can be different sensitive subgroups in the population reacting more strongly to indoor air pollution, linked to age, gender, allergic disposition (atopy), personality traits, stress, dietary habits, and certain types of medication. More research is needed on sensitive subgroups in a broader perspective. Investigations are needed on gene-environment interaction and gene expression in relation to different types of indoor exposure. There is a needed to continuously evaluate the health consequences of new building technologies and to perform small-scale testing of new building materials in real buildings before they are commonly used in large-scale production. It is a different task to control chemical emissions from building materials. Emission testing of building materials at dry laboratory conditions may not be relevant to evaluate chemical emissions in building with dampness. More research is needed to identify types of dampness-related exposure and etiology behind health effects of dampness and mould in buildings. There is a need to apply modern statistical methods to study multiple interactions between different VOC and other indoor factors in indoor environments with respect to health effects. Existing computer-based simulation models should be used to evaluate the risk of dampness and indoor mould growth when designing new buildings. Risk constructions, known to have a high probability for dampness and mould, should be avoided. Relevant authorities on national and international levels should set standards for concentrations of specific VOC in indoor air. Hopefully, in the future, there will be mandatory check-ups and checklists for quality improvements in the built environment. Epidemiological studies are needed on health consequences of energy use and energy saving in buildings in different climate zones, as well as on health consequences of climate change. Adaption of buildings and architectural interventions are needed to counteract the health consequences of climate change.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 159.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Locher WG. Max von Pettenkofer (1818–1901) as a pioneer of modern hygiene and preventive medicine. Environ Health Prev Med. 2007;12:238–45.

    Article  Google Scholar 

  2. Rocci S, Rebouex G. European birth cohorts. Early life exposure to microorganisms and health impact. Rev Mal Respir. 2017;34:635–44.

    Article  Google Scholar 

  3. Sparks JA, O’Reilly EJ, Barbhaiya M, Tedeschi SK, Malspeis S, Lu B, Willett WC, Costenbader KH, Karlson EW. Associations of fish intake and smoking with risk of rheumatoid arthritis and age of onset. A prospective cohort study. BMC Musculoskelet Disord. 2019;20(1):2.

    Article  Google Scholar 

  4. Norbäck D, Zock JP, Plana E, Heinrich J, Svanes C, Sunyer J, Künzli N, Villani S, Olivieri M, Soon A, Jarvis D. Mould and dampness in dwelling places, and onset of asthma: the population-based cohort ECRHS. Occup Environ Med. 2013;70:325–31.

    Article  Google Scholar 

  5. Gunnbjörnsdottir MI, Franklin KA, Norbäck D, Björnsson E, Gislason D, Lindberg E, Svanes C, Omenaas E, Norrman E, Jogi R, Jensen EJ, Dahlman-Höglund A, Janson C, RHINE Study Group. Prevalence and incidence of respiratory symptoms in relation to dampness: the RHINE study. Thorax. 2006;61:221–5.

    Article  Google Scholar 

  6. Ho SM, Johnson A, Tarapore P, Janakiram V, Zhang X, Leung YK. Environmental epigenetics and its implication on disease risk and health outcomes. ILAR J. 2012;53:289–305.

    Article  Google Scholar 

  7. Spartano NL, Davis-Plourde KL, Himali JJ, Murabito JM, Vasan RS, Beiser AS, Seshadri S. Self-reported physical activity and relations to growth and neurotropic factors in diabetes mellitus: the Framingham offspring study. J Diabetes Res. 2019;2019:2718465.

    Article  Google Scholar 

  8. Kuiper IN, Svanes C, Benediktsdottir B, Bertelsen RJ, Bråbäck L, Dharmage SC, Holm M, Janson C, Jogi R, Malinovschi A, Matheson M, Moratalla JM, Real FG, Sanchez-Ramos JL, Schlünssen V, Timm S, Johannessen A. Agreement in reporting of asthma by parents or offspring-the RHINESSA generation study. BMC Plum Med. 2018;18:122.

    Article  Google Scholar 

  9. Timm S, Frydenberg M, Abrahamson MJ, Bertelsen RJ, Bråbäck L, Benediktsdottir B, Gislason T, Holm M, Janson C, Jogi R, Johannessen A, Kim JL, Malinovschi A, Mishra G, Moratalla J, Sigsgaard T, Svanes C, Schlünssen V. Asthma and selective migration from farming environments in a three-generation cohort study. Eur J Epidemiol. 2019;34(6):601–9.

    Article  Google Scholar 

  10. Sauni R, Verbeek JH, Uitti J, Jauhiainen M, Kreiss K, Sigsgaard T. Remediating buildings damaged by dampness and mould for preventing or reducing respiratory tract symptoms, infections and asthma. Cochrane Database Syst Rev. 2015;2015:CD0077897.

    Google Scholar 

  11. Thomson H, Thomas S, Sellstrom E, Petticrew M. Housing improvements for health and associated socio-economic outcomes. Cochrane Database Syst Rev. 2013;2013:CD008657.

    Google Scholar 

  12. Gøtsche PC, Johansen HK. House dust mite control measures for asthma. Cochrane Database Syst Rev. 2008;2008:CD001187.

    Google Scholar 

  13. Norbäck D, Wieslander G. Biomarkers and chemosensory irritations. Int Arch Occup Environ Health. 2002;75:298–304.

    Article  Google Scholar 

  14. De Oliviera BF, Chacra AP, Frachures TS, Vallochi A, Hacon S. A curative review of recent literature of biomarkers used for assessing air pollution exposures and effects in humans. J Toxicol Environ Health B Crit Rev. 2014;17:369–410.

    Article  Google Scholar 

  15. Svanes C, Koplin J, Skulstad SM, Johannessen A, Bertelsen RJ, Benediktsdottir B, Bråbäck L, Elie Carsin A, Dharmage S, Dratva J, Forsberg B, Gislason T, Heinrich J, Holm M, Janson C, Jarvis D, Jogi R, Krauss-Etschmann S, Lindberg E, Macsali F, Malinovschi A, Modig L, Norbäck D, Omenaas E, Waatevik Saure E, Sigsgaard T, Skorge TD, Svanes Ø, Toren K, Torres C, Schlünssen V, Real F. Father’s environment before conception and asthma risk in his children: a multi-generation analysis of the respiratory health in northern Europe study. Int J Epidemiol. 2017;46:235–45.

    PubMed  Google Scholar 

  16. Radon K. The two sides of the “endotoxin coin”. Occup Environ Med. 2006;63:73–8.

    Article  CAS  Google Scholar 

  17. Runeson S, Norbäck D, Klinteberg B, Edling C. The influence of personality, measured by the Karolinska scales of personality (KSP), on symptoms among subjects in suspected sick buildings. Indoor Air. 2004;14:394–404.

    Article  CAS  Google Scholar 

  18. Deng Q, Deng L, Lu C, Li Y, Norbäck D. Parental stress and air pollution increase childhood asthma in China. Environ Res. 2008;165:23–31.

    Article  Google Scholar 

  19. Kim JL, Elfman L, Mi Y, Johansson M, Smedje G, Norbäck D. Current asthma and respiratory symptoms among pupils in relation to dietary factors and allergens in the school environment. Indoor Air. 2005;15:170–82.

    Article  CAS  Google Scholar 

  20. Norbäck D, Lu C, Zhang Y, Li B, Zhao Z, Huang C, Zhang X, Qian H, Sun Y, Wang J, Liu W, Sundell J, Deng Q. Sources of indoor particulate matter (PM) and outdoor air pollution in China in relation to asthma, wheeze, rhinitis and eczema among pre-school children: synergistic effects between antibiotics use and PM10 and second hand smoke. Environ Int. 2019;125:252–60.

    Article  Google Scholar 

  21. Castro-Giner F, Künzli N, Jacquemin B, Forsberg B, de Cid R, Sunyer J, Jarvis D, Briggs D, Vienneau D, Norback D, González JR, Guerra S, Janson C, Antó JM, Wjst M, Heinrich J, Estivill X, Kogevinas M. Traffic-related air pollution, oxidative stress genes, and asthma (ECHRS). Environ Health Perspect. 2009;117:1919–24.

    Article  CAS  Google Scholar 

  22. Amaral AF, Ramasamy A, Castro-Giner F, Minelli C, Accordini S, Sørheim IC, Pin I, Kogevinas M, Jogi R, Balding DJ, Norbäck D, Verlato G, Olivieri M, Probst-Hensch N, Janson C, Zock JP, Heinrich J, Jarvis DL. Interaction between gas cooking and GSTM1 null genotype in bronchial responsiveness: results from the European Community Respiratory Health Survey. Thorax. 2014;69:558–64.

    Article  Google Scholar 

  23. Tsai CH, Tung KY, Chen CH, Lee YL. Tumour necrosis factor G-308A polymorphism modifies the effect of home dampness on childhood asthma. Occup Environ Med. 2011;68:771–6.

    Article  CAS  Google Scholar 

  24. Wang IJ, Tsai CH, Kuo NW, Chiang BL, Tung KY, Lee YL. Home dampness, beta-2 adrenergic receptor genetic polymorphisms, and asthma phenotypes in children. Environ Res. 2012;118:72–8.

    Article  CAS  Google Scholar 

  25. Su MV, Tung KY, Liang PH, Tsai CH, Kuo NW, Lee YL. Gene-gene and gene-environmental interactions of childhood asthma: a multifactor dimension reduction approach. PLoS One. 2012;7:e30684.

    Article  Google Scholar 

  26. Oeder S, Jörres RA, Weichenmeier I, Pusch G, Schober F, Behrendt H, Schierl R, Kronseder A, Nowak D, Dietrich S, Fernadez-Caldas E, Lintelmann J, Zimmermann R, Lang G, Mages J, Fromme H, Butlers JT. Airborne indoor particles from schools are more toxic than outdoor particles. Am J Respir Cell Mol Biol. 2012;47:575–682.

    Article  CAS  Google Scholar 

  27. Lundholm M, Lavrell G, Mathiasson L. Self-leveling mortar as a possible cause of symptoms associated with “sick building syndrome”. Arch Environ Health. 1990;45:135–40.

    Article  CAS  Google Scholar 

  28. Wieslander G, Norbäck D, Björnsson E, Janson C, Boman G. Asthma and the indoor environment. The significance of emission of formaldehyde and volatile organic compounds from newly painted indoor surfaces. Int Arch Occup Environ Health. 1997;69:115–24.

    Article  CAS  Google Scholar 

  29. Lampa E, Lind L, Lind PM, Bornefalk-Hermansson A. The identification of complex interactions in epidemiology and toxicology: a simulation study of boosted regression trees. Environ Health. 2014;13:57.

    Article  Google Scholar 

  30. Cai GH, Mälarstig B, Kumlin A, Johansson I, Janson C, Norbäck D. Fungal DNA and pet allergen levels in Swedish day care centers and associations with building characteristics. J Environ Monit. 2011;13:2018–24.

    Article  CAS  Google Scholar 

  31. Norbäck D, Lampa E, Engvall K. Asthma, allergy and eczema among adults in multifamily houses in Stockholm (3HE-study)-associations with building characteristics, home environment and energy use for heating. PLoS One. 2014;9:e112960.

    Article  Google Scholar 

  32. Norbäck D, Zock JP, Plana E, Heinrich J, Tischer C, Jacobsen Bertelsen R, Sunyer J, Künzli N, Villani S, Olivieri M, Verlato G, Soon A, Schlünssen V, Gunnbjörnsdottir MI, Jarvis D. Building dampness and mould in European homes in relation to climate, building characteristics and socio-economic status: the European Community Respiratory Health Survey ECRHSII. Indoor Air. 2017;27:921–32.

    Article  Google Scholar 

  33. Haines A, Ebi K. The imperative for climate action to protect health. N Engl J Med. 2019;380:263–73.

    Article  Google Scholar 

  34. Demain JG. Climate change and the impact on respiratory and allergic disease: 2018. Curr Allergy Asthma Rep. 2018;18:22.

    Article  Google Scholar 

  35. Prior JH, Connon IL, McIntyre E, Adams J, Capon A, kent J, Rissel C, Thiomas LE, Thomson SM, Westcott H. Built environment interventions for human and planetary health: integrating health in climate change adaption and mitigation. Public Health Res Pract. 2018;28:2841831.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Dan Norbäck .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Nature Singapore Pte Ltd.

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Norbäck, D. (2020). Future Directions of Research on Indoor Environment, Indoor Air Quality (IAQ), and Health. In: Kishi, R., Norbäck, D., Araki, A. (eds) Indoor Environmental Quality and Health Risk toward Healthier Environment for All. Current Topics in Environmental Health and Preventive Medicine. Springer, Singapore. https://doi.org/10.1007/978-981-32-9182-9_17

Download citation

  • DOI: https://doi.org/10.1007/978-981-32-9182-9_17

  • Published:

  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-32-9181-2

  • Online ISBN: 978-981-32-9182-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics