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Photodynamic Therapy for Lung Cancer

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Respiratory Endoscopy
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Abstract

Photodynamic therapy (PDT) causes a photodynamic reaction by a low-power laser irradiation tumor affinity light-sensitive material, the energy conversion of when the transition to the excited state a result, the antitumor effect by producing the active oxygen. Be familiar with handling of equipment and use the right probe for a particular device. Check whether the laser equipment is operating correctly prior to administration of the photosensitizer. Sequential electronic scope cannot be used. PDT for advanced lung cancer is currently an off-label treatment modality, at least in Japan. The dose of laser irradiation has not been established, but it has been proven to be superior to ablation therapy. PDT for peripheral-type lung cancer is currently an off-label treatment, so its performance needs ethics committee review and should be in the context of a clinical trial. The laser irradiation dose for such purpose has not been established.

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References

  1. Diaz-Jimenez JP, Martinez-Ballarin JE, Llunell A, et al. Efficacy and safety of photodynamic therapy versus Nd-YAG laser resection in NSCLC with airway obstruction. Eur Respir J. 1999;14:800–15.

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Correspondence to Takaaki Tsuchida .

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Tsuchida, T., Izumo, T. (2017). Photodynamic Therapy for Lung Cancer. In: Izumo, T., Sasada, S., Aso, T., Nasu, K., Arai, Y. (eds) Respiratory Endoscopy. Springer, Singapore. https://doi.org/10.1007/978-981-287-916-5_29

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  • DOI: https://doi.org/10.1007/978-981-287-916-5_29

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-287-914-1

  • Online ISBN: 978-981-287-916-5

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