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Gastroesophageal Reflux Disease

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Helicobacter pylori

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Abstract

Helicobacter pylori (H. pylori) infection has an influence on the development of gastroesophageal reflux “indirectly” by altering gastric acid secretion. The outcome of H. pylori infection and eradication depends on its distribution of inflammation. If the antrum is mainly infected with H. pylori, acid secretion would increase, and gastroesophageal reflux disease (GERD) can be developed more easily. On the other hand, if the body is infected, acid secretion would decrease, and the possibility of GERD development gets lower. The outcome of H. pylori eradication also depends on the distribution of H. pylori-infected area. If H. pylori has affected the antrum, GERD symptoms tend to be improved after the eradication. On the other hand, when it has affected the body, GERD symptoms might be getting worse after the eradication. However, H. pylori eradication does not need to be hesitated just because of these trends. H. pylori eradication itself does not seem to develop GERD. It would be more correct to explain this that H. pylori infection has been masking GERD symptoms and H. pylori eradication would relieve the inflammation and no longer mask the GERD symptoms.

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Authors and Affiliations

  1. Department of Internal Medicine, Gyeongsang National University Hospital, 79 Gangnam-ro, Jinju-si, Gyeongsangnam-do, 52727, South Korea

    Jinjoo Kim MD

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  1. Jinjoo Kim MD
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Correspondence to Jinjoo Kim MD .

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Editors and Affiliations

  1. Seoul National University, Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea (Republic of)

    Nayoung Kim

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Kim, J. (2016). Gastroesophageal Reflux Disease. In: Kim, N. (eds) Helicobacter pylori. Springer, Singapore. https://doi.org/10.1007/978-981-287-706-2_29

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  • DOI: https://doi.org/10.1007/978-981-287-706-2_29

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