Abstract
Chondroid matrix is seen in lesions comprised of chondrocyte proliferation. The radiographic appearance can be described as ring-and-arc, punctate, curved, stippled, or coarser flocculent foci of calcification. The radiographic presence of chondroid matrix implies mature cartilage production; however, this may be seen in both benign and malignant lesions. A benign enchondroma may be radiographically identical to a low-grade chondrosarcoma in the absence of aggressive features such as cortical destruction and soft tissue extension. The location of the chondroid matrix within the bone and the age of the patient help narrow the differential diagnosis. A chondroid lesion in the epiphysis of a pediatric patient is almost certainly a chondroblastoma, whereas the same lesion in the third or fourth decades of life may represent a clear cell chondrosarcoma. An intramedullary lesion in the metaphysis of an adult patient may represent an enchondroma or chondrosarcoma.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Suggested Reading
Benign: Osteochondroma
Kenan S, Abdelwahab IF, Klein MJ, Hermann G, Lewis MM. Lesions of juxtacortical origin (surface lesions of bone). Skelet Radiol. 1993;22:337–57.
Ludwig K. Cartilage tumours. In: Davies AM, Sundaram M, James SLJ, editors. Imaging of bone tumors and tumor-like lesions: techniques and applications. 1st ed. Berlin: Springer; 2009. p. 225–50.
Motamedi K, Seeger LL. Benign bone tumors. Radiol Clin N Am. 2011;49:1115–34.
Murphey MD, Choi JJ, Kransdorf MJ, Flemming DJ, Gannon FH. Imaging of osteochondroma: variants and complications with radiologic-pathologic correlation. Radiographics. 2000;20:1407–34.
Nichols RE, Dixon LB. Radiographic analysis of solitary bone lesions. Radiol Clin N Am. 2011;49:1095–114.
Benign : Enchondroma
Currie JW, Davis KW, Lafita VS, Blankenbaker DG, De Smet AA, Rosas H, Lee KS. Musculoskeletal mnemonics: differentiating features. Curr Probl Diagn Radiol. 2011;40:45–71.
Eisenberg RL. Bubbly lesions of bone. AJR Am J Roentgenol. 2009;193:W79–94.
Ludwig K. Cartilage tumours. In: Davies AM, Sundaram M, James SLJ, editors. Imaging of bone tumors and tumor-like lesions: techniques and applications. 1st ed. Berlin: Springer; 2009. p. 225–50.
Motamedi K, Seeger LL. Benign bone tumors. Radiol Clin N Am. 2011;49:1115–34.
Nichols RE, Dixon LB. Radiographic analysis of solitary bone lesions. Radiol Clin N Am. 2011;49:1095–114.
Benign: Periosteal Chondroma (Juxtacortical Chondroma)
Kenan S, Abdelwahab IF, Klein MJ, Hermann G, Lewis MM. Lesions of juxtacortical origin (surface lesions of bone). Skelet Radiol. 1993;22:337–57.
Ludwig K. Cartilage tumours. In: Davies AM, Sundaram M, James SLJ, editors. Imaging of bone tumors and tumor-like lesions: techniques and applications. 1st ed. Berlin: Springer; 2009. p. 225–50.
Motamedi K, Seeger LL. Benign bone tumors. Radiol Clin N Am. 2011;49:1115–34.
Seeger LL, Yao L, Eckardt JJ. Surface lesions of bone. Radiology. 1998;206:17–33.
Benign: Chondromyxoid Fibroma
Ludwig K. Cartilage tumours. In: Davies AM, Sundaram M, James SLJ, editors. Imaging of bone tumors and tumor-like lesions: techniques and applications. 1st ed. Berlin: Springer; 2009. p. 225–50.
Motamedi K, Seeger LL. Benign bone tumors. Radiol Clin N Am. 2011;49:1115–34.
Benign: Subungual Exostosis
Higuchi K, Oiso N, Yoshida M, Kawada A. Preoperative assessment using magnetic resonance imaging for subungual exostosis beneath the proximal region of the nail plate. Case Rep Dermatol. 2011;3:155–7.
Kenan S, Abdelwahab IF, Klein MJ, Hermann G, Lewis MM. Lesions of juxtacortical origin (surface lesions of bone). Skelet Radiol. 1993;22:337–57.
Ludwig K. Cartilage tumours. In: Davies AM, Sundaram M, James SLJ, editors. Imaging of bone tumors and tumor-like lesions: techniques and applications. 1st ed. Berlin: Springer; 2009. p. 225–50.
Murphey MD, Choi JJ, Kransdorf MJ, Flemming DJ, Gannon FH. Imaging of osteochondroma: variants and complications with radiologic-pathologic correlation. Radiographics. 2000;20:1407–34.
Seeger LL, Yao L, Eckardt JJ. Surface lesions of bone. Radiology. 1998;206:17–33.
Benign: Bizarre Parosteal Osteochondromatous Proliferation
Kenan S, Abdelwahab IF, Klein MJ, Hermann G, Lewis MM. Lesions of juxtacortical origin (surface lesions of bone). Skelet Radiol. 1993;22:337–57.
Seeger LL, Yao L, Eckardt JJ. Surface lesions of bone. Radiology. 1998;206:17–33.
Torreggiani WC, Munk PL, Al-Ismail K, O'Connell JX, Nicolaou S, Lee MJ, Masri BA. MR imaging features of bizarre parosteal osteochondromatous proliferation of bone (Nora’s lesion). Eur J Radiol. 2001; 40:224–31.
Benign: Chondroblastoma
Kaim AH, Hügli R, Bonél HM, Jundt G. Chondroblastoma and clear cell chondrosarcoma: radiological and MRI characteristics with histopathological correlation Skeletal Radiol. 2002;31:88–95.
Ludwig K. Cartilage tumours. In: Davies AM, Sundaram M, James SLJ, editors. Imaging of bone tumors and tumor-like lesions: techniques and applications. 1st ed. Berlin: Springer; 2009. p. 225–50.
Motamedi K, Seeger LL. Benign bone tumors. Radiol Clin N Am. 2011;49:1115–34.
Malignant: Conventional Intramedullary Chondrosarcoma
Czerniak B. Malignant cartilage tumors. In: Czerniak B, editor. Dorfman and Czerniak’s bone tumors. 2nd ed. Philadelphia: Elsevier Saunders; 2016. p.474–569.
Kaste SC. Imaging pediatric bone sarcomas. Radiol Clin N Am. 2011; 49:749–65.
Ludwig K. Cartilage tumours. In: Davies AM, Sundaram M, James SLJ, editors. Imaging of bone tumors and tumor-like lesions: techniques and applications. 1st ed. Berlin: Springer; 2009. p. 225–50.
Murphey MD, Flemming DJ, Boyea SR, Bojescul JA, Sweet DE, Temple HT. Enchondroma versus chondrosarcoma in the appendicular skeleton: differentiating features. Radiographics. 1998;18:1213–37
Rajiah P, Ilaslan H, Sundaram M. Imaging of primary malignant bone tumors (nonhematological). Radiol Clin N Am. 2011;49:1135–61.
Malignant: Periosteal/Juxtacortical Chondrosarcoma
Czerniak B. Malignant cartilage tumors. In: Czerniak B, editor. Dorfman and Czerniak’s bone tumors. 2nd ed. Philadelphia: Elsevier Saunders; 2016. p.474–569.
Kenan S, Abdelwahab IF, Klein MJ, Hermann G, Lewis MM. Lesions of juxtacortical origin (surface lesions of bone). Skelet Radiol. 1993;22:337–57.
Ludwig K. Cartilage tumours. In: Davies AM, Sundaram M, James SLJ, editors. Imaging of bone tumors and tumor-like lesions: techniques and applications. 1st ed. Berlin: Springer; 2009. p. 225–50.
Rajiah P, Ilaslan H, Sundaram M. Imaging of primary malignant bone tumors (nonhematological). Radiol Clin N Am. 2011;49:1135–61.
Seeger LL, Yao L, Eckardt JJ. Surface lesions of bone. Radiology. 1998;206:17–33.
Malignant: Mesenchymal Chondrosarcoma
Czerniak B. Malignant cartilage tumors. In: Czerniak B, editor. Dorfman and Czerniak’s bone tumors. 2nd ed. Philadelphia: Elsevier Saunders; 2016. p. 474–569.
Ludwig K. Cartilage tumours. In: Davies AM, Sundaram M, James SLJ, editors. Imaging of bone tumors and tumor-like lesions: techniques and applications. 1st ed. Berlin: Springer; 2009. p. 225–50.
Rajiah P, Ilaslan H, Sundaram M. Imaging of primary malignant bone tumors (nonhematological). Radiol Clin N Am. 2011;49:1135–61.
Malignant: Clear Cell Chondrosarcoma
Czerniak B. Malignant cartilage tumors. In: Czerniak B, ed. Dorfman and Czerniak’s bone tumors. 2nd ed. Philadelphia: Elsevier Saunders; 2016. p. 474–569.
Kaim AH, Hügli R, Bonél HM, Jundt G. Chondroblastoma and clear cell chondrosarcoma: radiological and MRI characteristics with histopathological correlation Skeletal Radiol. 2002;31:88–95.
Ludwig K. Cartilage tumours. In: Davies AM, Sundaram M, James SLJ, editors. Imaging of bone tumors and tumor-like lesions: techniques and applications. 1st ed. Berlin: Springer; 2009. p. 225–50.
Rajiah P, Ilaslan H, Sundaram M. Imaging of primary malignant bone tumors (nonhematological). Radiol Clin N Am. 2011;49:1135–61.
Malignant: Dedifferentiated Chondrosarcoma
Czerniak B. Malignant cartilage tumors. In: Czerniak B, editor. Dorfman and Czerniak’s bone tumors. 2nd ed. Philadelphia: Elsevier Saunders; 2016. p. 474–569.
Ludwig K. Cartilage tumours. In: Davies AM, Sundaram M, James SLJ, editors. Imaging of bone tumors and tumor-like lesions: techniques and applications. 1st ed. Berlin: Springer; 2009. p. 225–50.
MacSweeney F, Darby A, Saifuddin A. Dedifferentiated chondrosarcoma of the appendicular skeleton: MRI-pathological correlation. Skelet Radiol. 2003;32:671–8.
Rajiah P, Ilaslan H, Sundaram M. Imaging of primary malignant bone tumors (nonhematological). Radiol Clin N Am. 2011;49:1135–61.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2017 Springer Science+Business Media Singapore
About this chapter
Cite this chapter
Kang, H.S., Ahn, J.M., Kang, Y. (2017). Chondrogenic Tumors. In: Oncologic Imaging: Bone Tumors. Springer, Singapore. https://doi.org/10.1007/978-981-287-703-1_3
Download citation
DOI: https://doi.org/10.1007/978-981-287-703-1_3
Publisher Name: Springer, Singapore
Print ISBN: 978-981-287-702-4
Online ISBN: 978-981-287-703-1
eBook Packages: MedicineMedicine (R0)