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Ionic Concentration and Action Potential Differences Between a Healthy and Alzheimer’s Disease Person

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Data Science and Analytics (REDSET 2019)

Part of the book series: Communications in Computer and Information Science ((CCIS,volume 1229))

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Abstract

Depressed \( Na^{ + } \)/\( K^{ + } \) ATParse amount and diminished glutamate agreement in Alzheimer’s disease brain is coupled through Alzheimer’s disease. Cellular ion disparity might be its outcome. As soon as the cell is energized by some inner or exterior spur then action potential in the shape of very small pulses arises. It overreaches the decisive threshold of the membrane. The action potential initiation observed in cortical neurons is not capable to be explained by HH type models. This paper reviews HH model and shows the difference between a HH model with its sodium and potassium ion currents and the ionic concentrations of sodium and potassium of a person with Alzheimer’s disease in it. Results are generated in form of graphs. This model is implemented in Matlab software to fairly accurate the differential equations. By using HH model, further parameters are created, \( Na^{ + } \) and \( K^{ + } \). The new parameters need to be carefully considered and analyzed.

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Authors and Affiliations

  1. Computer Science Department, K. R. Mangalam University, Gurugram, India

    Shruti Gupta & Kaushal Kumar

  2. Computer Science Department, IILM College of Engineering and Technology, Gurugram, India

    Jyotsna Singh

Authors
  1. Shruti Gupta
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  2. Jyotsna Singh
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  3. Kaushal Kumar
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Corresponding authors

Correspondence to Shruti Gupta , Jyotsna Singh or Kaushal Kumar .

Editor information

Editors and Affiliations

  1. GD Goenka University, Gurugram, India

    Usha Batra

  2. GD Goenka University, Sohna, Haryana, India

    Nihar Ranjan Roy

  3. University of Arkansas, Fayetteville, AR, USA

    Brajendra Panda

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Gupta, S., Singh, J., Kumar, K. (2020). Ionic Concentration and Action Potential Differences Between a Healthy and Alzheimer’s Disease Person. In: Batra, U., Roy, N., Panda, B. (eds) Data Science and Analytics. REDSET 2019. Communications in Computer and Information Science, vol 1229. Springer, Singapore. https://doi.org/10.1007/978-981-15-5827-6_23

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  • DOI: https://doi.org/10.1007/978-981-15-5827-6_23

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-15-5826-9

  • Online ISBN: 978-981-15-5827-6

  • eBook Packages: Computer ScienceComputer Science (R0)

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