Abstract
With the development of modern industry and agriculture, human is chronically exposed to various toxic environmental pollutants, such as heavy metals, pesticides, antibiotics, other persistent organic pollutants, and some biological contaminants. Most of them are non-degradable and can be accumulated in bodies, which poses various adverse health concern as well as alterations in the metabolic activity and/or the composition of the gut microbiota (GM). Conversely, pollutants-induced alterations of gut microbiota have been shown to modulate the toxicity of environmental pollutants to the host. Therefore, the occurrence of a lots of diseases is likely related with pollutant-altered gut microbiota. However, the physiological consequences of these alterations have not been studied in detail, especially the bidirectional correlation between the toxicological relevance of gut microbiota and host physiology. In this review, we aim to explore the modes and outcomes of different environmental pollutants on hosts health mainly from the perspective of GM based on the existing relevant studies. It is important for us to rationally manipulate the gut microbiota by the specific bacteria.
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Feng, P., Xiao, X., Zhou, T., Li, X. (2020). Effects of the Bio-accumulative Environmental Pollutants on the Gut Microbiota. In: Li, X., Liu, P. (eds) Gut Remediation of Environmental Pollutants. Springer, Singapore. https://doi.org/10.1007/978-981-15-4759-1_4
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