Abstract
Occupational skin diseases (OSD) represent 10–40% of all registered occupational diseases in most European countries, mostly comprising contact dermatitis, contact urticaria, and skin cancer as the most important OSD. Occupational contact dermatitis (OCD) is one of the most important occupational diseases, in general, and it is frequently present in dermatology practice. This clinical entity can be manifested as an effect of irritant or allergic reaction to certain hazards that are present at the workplace. The identification of concrete etiological occupational factor could be performed by skin tests with specific workplace allergens. The cessation of occupational exposure is the first and the most important step in the management of OCD. Occupational skin cancer (OSC) (basal cell carcinoma, squamous cell carcinoma, malignant melanoma) is a frequent malignant neoplasm and the most important etiological factor is occupational exposure to ultraviolet (UV) radiation, along with arsenic, polycyclic aromatic hydrocarbons, ionizing radiation, and trauma. The prevention of OSC should involve specific technical/organizational measures, personal protective measures, preventive medical examinations of workers, and educational activities.
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References
Sasseville D. Occupational contact dermatitis. Allergy Asthma Clin Immunol. 2008;4(2):59–65. https://doi.org/10.1186/1710-1492-4-2-59.
De Craecker W, Roskams N, De Beeck RO. Occupational skin diseases. In: Occupational skin diseases and dermal exposure in the European Union (EU-25): policy and practice overview. European Agency for Safety and Health at Work. 2008. https://osha.europa.eu/en/node/6875/file_view. Accessed 21 May 2019.
Johansen JD, Aalto-Korte K, Agner T, Andersen KE, Bircher A, Bruze M, et al. European Society of Contact Dermatitis guideline for diagnostic patch testing—recommendations on best practice. Contact Dermatitis. 2015;73:195–221.
Australian Safety and Compensation Council. Occupational contact dermatitis in Australia. Australian Government. 2005. https://www.safeworkaustralia.gov.au/system/files/documents/1702/occupational_contact_dermatitis_australia.pdf. Accessed 21 May 2019.
Canadian Centre for Occupational Health and Safety. Dermatitis, allergic contact. Canadian Centre for Occupational Health and Safety. 2016. https://www.ccohs.ca/oshanswers/diseases/allergic_derm.html. Accessed 21 May 2019.
Sasseville D. Occupational contact dermatitis. In: Encyclopedia of occupational health and safety. 4th ed. International Labour Office. 1998. http://www.iloencyclopaedia.org/part-i/skin-diseases/item/470-occupational-contact-dermatitis. Accessed 21 May 2019.
American Academy of Dermatology. Contact dermatitis. American Academy of Dermatology. 2011. https://www.aad.org/public/diseases/eczema/contact-dermatitis. Accessed 21 May 2019.
The Lewin Group, Inc. Contact dermatitis. In: The burden of skin diseases 2004. The Society for Investigative Dermatology, The American Academy of Dermatology Association. 2005. https://www.clnwash.com/pdf/BurdenofSkin%20Diseases2004_FinalSept05.pdf. Accessed 21 May 2019.
European Society of Contact Dermatitis. What is contact dermatitis. European Society of Contact Dermatitis. 2019. https://www.escd.org/contact-dermatitis/what-is-contact-dermatitis/. Accessed 21 May 2019.
Coenraads PJ, Uter W, Diepgen T. Epidemiology. In: Johansen JD, Frosch PJ, Lepoittevin JP, editors. Contact dermatitis. Berlin, Heidelberg: Springer; 2011. p. 193–214.
Alfonso JH, Bauer A, Bensefa-Colas L, Boman A, Bubas M, Constandt L, et al. Minimum standards on prevention, diagnosis and treatment of occupational and work-related skin diseases in Europe—position paper of the COST Action StanDerm (TD 1206). J Eur Acad Dermatol Venereol. 2017;31(Suppl 4):31–43. https://doi.org/10.1111/jdv.14319.
European Commission Employment Social Affairs and Equal Opportunities. Health and safety at work in Europe, (1999–2007). A statistical portrait. 2010th ed. Luxembourg: Publications Office of the European Union; 2010. https://ec.europa.eu/eurostat/documents/3217494/5718905/KS-31-09-290-EN.PDF/88eef9f7-c229-40de-b1cd-43126bc4a946. Accessed 21 May 2019.
Mahler V, Aalto-Korte K, Alfonso JH, Bakker JG, Bauer A, Bensefa-Colas L, et al. Occupational skin diseases: actual state analysis of patient management pathways in 28 European countries. J Eur Acad Dermatol Venereol. 2017;31(Suppl 4):12–30. https://doi.org/10.1111/jdv.14316.
Караџинска-Бислимовска Ј, Мијакоски Д. Професионален контактен дерматитис. In: Докиќ Д, editor. Алергологија. Скопје: Матица македонска; 2017. p. 223–30.
Adisesh A, Robinson E, Nicholson PJ, Sen D, Wilkinson M. Standards of Care Working Group. U.K. standards of care for occupational contact dermatitis and occupational contact urticaria. Br J Dermatol. 2013;168:1167–75. https://doi.org/10.1111/bjd.12256.
Sulzberger MB, Finnerud CW. Industrial dermatitis. Definitions and criteria of diagnosis. JAMA. 1938;111:1528–32. https://doi.org/10.1001/jama.1938.02790430012004.
Wise F, Sulzberger MB. Industrial dermatoses. Am Med. 1933;28:4–7.
El Batawi MA. Work-related diseases. A new program of the World Health Organization. Scand J Work Environ Health. 1984;10:341–6.
World Health Organization (WHO). Occupational health. Occupational and work-related diseases. World Health Organization (WHO). 2019. http://www.who.int/occupational_health/activities/occupational_work_diseases/en/. Accessed 21 May 2019.
Караџинска-Бислимовска Ј, Минов Ј, Ристеска-Куч С, Мијакоски Д, Столески С. Медицина на трудот. 1st ed. Универзитет Св. Кирил и Методиј, Медицински факултет: Скопје; 2011.
International Labour Organization (ILO). R194 - List of Occupational Diseases Recommendation No. 194. International Labour Organization (ILO). 2002. https://www.ilo.org/dyn/normlex/en/f?p=1000:12100:0::NO::P12100_INSTRUMENT_ID,P12100_LANG_CODE:312532,en:NO. Accessed 21 May 2019.
Johansen J, Menne T, Christophersen J, Kaaber K, Veien N. Changes in the pattern of sensitization to common contact allergens in Denmark between 1985-86 and 1997-98, with a special view to the effect of preventive strategies. Br J Dermatol. 2000;142(3):490–5.
Lammintausta K. Hand eczema. 3rd ed. Boca Raton: CRC; 2000.
National Occupational Health and Safety Commission. Approved criteria for classifying hazardous substances [NOHSC:1008(2004)]. 3rd ed. Canberra: Commonwealth of Australia; 2004.
Nixon R, Frowen K. Allergic contact dermatitis to epoxy resins. J Occup Health Safety Aust NZ. 1991;7:417–24.
Benedetti J. Structure and function of the skin. In: Merck manual for the professional. Merck Sharp & Dohme Corp. 2019. https://www.merckmanuals.com/home/skin-disorders/biology-of-the-skin/structure-and-function-of-the-skin. Accessed 21 May 2019.
Kim S, Yang SW, Kim H, Kim SH, Kim SJ, Park SM, et al. Association between P478S polymorphism of the filaggrin gene and atopic dermatitis. Indian J Med Res. 2013;138(6):922–7.
Park KY, Li K, Seok J, Seo SJ. An analysis of the filaggrin gene polymorphism in Korean atopic dermatitis patients. J Korean Med Sci. 2016;31(7):1136–42. https://doi.org/10.3346/jkms.2016.31.7.1136.
Novak N, Baurecht H, Schäfer T, Rodriguez E, Wagenpfeil S, Klopp N, et al. Loss-of-function mutations in the filaggrin gene and allergic contact sensitization to nickel. J Invest Dermatol. 2008;128(6):1430–5. https://doi.org/10.1038/sj.jid.5701190.
Visser MJ, Landeck L, Campbell LE, McLean WHI, Weidinger S, Calkoen F, et al. Impact of atopic dermatitis and loss-of-function mutations in the filaggrin gene on the development of occupational irritant contact dermatitis. Br J Dermatol. 2013;168(2):326–32. https://doi.org/10.1111/bjd.12083.
West HC, Bennett CL. Redefining the role of Langerhans cells as immune regulators within the skin. Front Immunol. 2018;5(8):1941. https://doi.org/10.3389/fimmu.2017.01941.
Igyártó BZ, Kaplan DH. Antigen presentation by Langerhans cells. Curr Opin Immunol. 2013;25(1):115–9. https://doi.org/10.1016/j.coi.2012.11.007.
Karlsson I, Samuelsson K, Simonsson C, Stenfeldt A, Nilsson U, Ilag LL, et al. The fate of a hapten—from the skin to modification of macrophage migration inhibitory factor (MIF) in lymph nodes. Sci Rep. 2018;8:2895.
Helm TN. What are prehaptens associated with allergic contact dermatitis? In: Medscape allergy and immunology. WebMD LLC. 2019. https://www.medscape.com/answers/1049216-4795/what-are-prehaptens-associated-with-allergic-contact-dermatitis. Accessed 21 May 2019.
Scientific Committee on Consumer Safety (SCCS). Opinion on fragrance allergens in cosmetic products. Brussels: European Commission, Health & Consumers Directorate; 2012.
Christmas P. Toll-Like receptors: sensors that detect infection. Nat Educ. 2010;3(9):85.
Helm TN. What is the role of haptens in the pathophysiology of allergic contact dermatitis? In: Medscape allergy and immunology. WebMD LLC. 2019. https://www.medscape.com/answers/1049216-4796/what-is-the-role-of-haptens-in-the-pathophysiology-of-allergic-contact-dermatitis. Accessed 21 May 2019.
Helm TN. Allergic contact dermatitis. In: Medscape. WebMD LLC. 2019. https://emedicine.medscape.com/article/1049216-overview. Accessed 21 May 2019.
В’лчкова-Лашкоска МТ, Старова А. Клиничка дерматологија со практикум за студенти и лекари. 1st ed. Хиб Дреско: Скопје; 1998.
Ngan V. Irritant contact dermatitis. In: DermNet NZ. DermNet New Zealand Trust. 2003. https://www.dermnetnz.org/topics/irritant-contact-dermatitis/. Accessed 21 May 2019.
Birmingham DJ. Overview: occupational skin diseases. In: Encyclopedia of occupational health and safety. 4th ed. International Labour Office. 1998. http://www.iloencyclopaedia.org/part-i-47946/skin-diseases/12/overview-occupational-skin-diseases. Accessed 21 May 2019.
Schmitt J, Seidler A, Diepgen TL, Bauer A. Occupational ultraviolet light exposure increases the risk for the development of cutaneous squamous cell carcinoma: a systematic review and meta-analysis. Br J Dermatol. 2011;164:291–307. https://doi.org/10.1111/j.1365-2133.2010.10118.x.
Bauer A, Diepgen TL, Schmitt J. Is occupational solar ultraviolet irradiation a relevant risk factor for basal cell carcinoma? A systematic review and meta-analysis of the epidemiological literature. Br J Dermatol. 2011;165:612–25. https://doi.org/10.1111/j.1365-2133.2011.10425.x.
Alfonso JH, Sandvik A, John SM. Occupational skin cancer: sweeping the path to prevention. Occup Med. 2017;67:328–30.
Raissa F, Rahmayunita G, Menaldi L, Soemarko D. Occupational skin cancer and precancerous lesions. J Gen Pro DVI. 2016;1(3):77–85.
Gawkrodger DJ. Occupational skin cancers. Occup Med. 2004;54:458–63.
COST European Cooperation in Science and Technology: CA16216—Network on the Coordination and Harmonisation of European Occupational Cohorts. 2019.. http://omeganetcohorts.eu/. Accessed 21 May 2019.
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Mijakoski, D. (2020). Occupational Skin Diseases. In: Otsuki, T., Di Gioacchino, M., Petrarca, C. (eds) Allergy and Immunotoxicology in Occupational Health - The Next Step. Current Topics in Environmental Health and Preventive Medicine. Springer, Singapore. https://doi.org/10.1007/978-981-15-4735-5_9
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