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Endoscopic Diagnosis of Squamous Cell Carcinoma of the Esophagus

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Abstract

Recent advance in endoscopic imaging technology enables the endoscopists to detect esophageal squamous cell carcinoma (ESCC) more accurately than conventional white light imaging (WLI) and Lugol chromoendoscopy. Especially, a combination of narrow-band imaging (NBI) (Kaltenbach T, Gastroenterology 134:327–40, 2008) and magnifying endoscopy opened a brand new door of the endoscopic diagnostic field. NBI is classified in the category of equipment-based image-enhanced endoscope (IEE). Equipment-based IEE includes blue laser imaging (BLI) and i-scan optical enhancement (OE), which were developed after NBI.

Equipment-based IEE combined with magnifying endoscopy can visualize the microstructure of the squamous epithelial surface and microvasculature. Based on the morphological changes in these structures, we can make diagnosis ESCC more correctly and objectively. Therefore, in addition to the previous conventional strategy of endoscopic diagnosis, new diagnostic strategies based on morphological changes in the microvasculature and epithelial surface are now required and needed for the endoscopists.

In this chapter, we explained diagnostic strategies by practical endoscopy including detection, differential diagnosis, evaluation of depth of invasion, and histological confirmation of ESCC.

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Correspondence to Manabu Muto .

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Muto, M. (2020). Endoscopic Diagnosis of Squamous Cell Carcinoma of the Esophagus. In: Ando, N. (eds) Esophageal Squamous Cell Carcinoma. Springer, Singapore. https://doi.org/10.1007/978-981-15-4190-2_5

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  • DOI: https://doi.org/10.1007/978-981-15-4190-2_5

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-15-4189-6

  • Online ISBN: 978-981-15-4190-2

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