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Clinical Biomechanics and its Implications on Diabetic Foot pp 23–31Cite as

Pathomechanics of Diabetic Foot Syndrome

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Abstract

The understanding and reporting of the exact pathomechanics of a diabetic foot syndrome could be a highly complex process. However, the major pathogenesis mechanism is regulated by the changes in both metabolic and vascular factors. Under the metabolic factors, hyperglycemia has the highest contribution leading to axonal and microvascular injuries. The neuropathy symptoms are associated with damage to nerve fibers although less evidence is published regarding its pathogenesis. The possible explanation could be referenced to a study which found the microvascular defects using the sural nerve biopsy among patients with neuropathy. The mechanism for pathogenesis of diabetic foot syndrome could be well explained based on the etiological factors as discussed below.

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Authors and Affiliations

  1. LFAMS, Lovely Professional University, Jalandhar, Punjab, India

    Animesh Hazari

  2. Centre for Diabetic Foot Care and Research, MAHE, Manipal, Karnataka, India

    G. Arun Maiya

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  1. Animesh Hazari
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  2. G. Arun Maiya
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Correspondence to Animesh Hazari .

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Hazari, A., Maiya, G.A. (2020). Pathomechanics of Diabetic Foot Syndrome. In: Clinical Biomechanics and its Implications on Diabetic Foot. Springer, Singapore. https://doi.org/10.1007/978-981-15-3681-6_3

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  • DOI: https://doi.org/10.1007/978-981-15-3681-6_3

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-15-3680-9

  • Online ISBN: 978-981-15-3681-6

  • eBook Packages: MedicineMedicine (R0)

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