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Biomimicked Biomaterials pp 35–48Cite as

Injectable In Situ-Forming Hydrogels for Protein and Peptide Delivery

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1250))

Abstract

Injectable in situ-forming hydrogels have been used clinically in diverse biomedical applications. These hydrogels have distinct advantages such as easy management and minimal invasiveness. The hydrogels are aqueous formulations, and a simple injection at the target site replaces a traditional surgical procedure. Here, we review injectable in situ-forming hydrogels that are formulated by physical and chemical methods to deliver proteins and peptides. Prospects for using in situ-forming hydrogels for several specific applications are also discussed.

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Acknowledgment

This study was supported by a grant from Creative Materials Discovery Program through the National Research Foundation (2019M3D1A1078938) and Priority Research Centers Program (2019R1A6A1A11051471) funded by the National Research Foundation of Korea (NRF).

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Author notes

  1. Authors Seung Hun Park and Yun Bae Ji have equally contributed to this chapter.

Authors and Affiliations

  1. Department of Molecular Science and Technology, Ajou University, Suwon, South Korea

    Seung Hun Park, Yun Bae Ji, Joon Yeong Park, Hyeon Jin Ju, Mijeong Lee, Surha Lee, Jae Ho Kim, Byoung Hyun Min & Moon Suk Kim

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  1. Seung Hun Park
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Correspondence to Moon Suk Kim .

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Editors and Affiliations

  1. Institute of Cell & Tissue Engineering and College of Medicine, Catholic University of Korea, Seoul, Korea (Republic of)

    Heung Jae Chun

  2. 3B’s Research Group, I3Bs – Research Institute on Biomaterials, Biodegradables and Biomimetics, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, University of Minho, Guimarães, Portugal

    Rui L. Reis

  3. Department of Industrial Engineering and BIOtech Research Center, University of Trento, Trento, Italy

    Antonella Motta

  4. Department of BIN Convergence Technology, Department of Polymer Nano Science & Technology and Polymer BIN Research Center, Jeonbuk National University, Jeonju, Korea (Republic of)

    Gilson Khang

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Park, S.H. et al. (2020). Injectable In Situ-Forming Hydrogels for Protein and Peptide Delivery. In: Chun, H., Reis, R., Motta, A., Khang, G. (eds) Biomimicked Biomaterials. Advances in Experimental Medicine and Biology, vol 1250. Springer, Singapore. https://doi.org/10.1007/978-981-15-3262-7_3

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