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Application of Gellan Gum-Based Scaffold for Regenerative Medicine

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Bioinspired Biomaterials

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1249 ))

Abstract

Gellan gum (GG) is a linear microbial exopolysaccharide which is derived naturally by the fermentation process of Pseudomonas elodea. Application of GG in tissue engineering and regeneration medicine (TERM) is already over 10 years and has shown great potential. Although this biomaterial has many advantages such as biocompatibility, biodegradability, nontoxic in nature, and physical stability in the presence of cations, a variety of modification methods have been suggested due to some disadvantages such as mechanical properties, high gelation temperature, and lack of attachment sites. In this review, the application of GG-based scaffold for tissue engineering and approaches to improve GG properties are discussed. Furthermore, a recent trend and future perspective of GG-based scaffold are highlighted.

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Acknowledgments

This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT & Future Planning (NRF-2017R1A2B3010270) and Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health and Welfare, Republic of Korea (HI15C2996).

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Authors and Affiliations

  1. Department of BIN Convergence Technology, Department of Polymer Nano Science & Technology and Polymer BIN Research Center, Jeonbuk National University, Jeonju, South Korea

    Joo Hee Choi, Wonchan Lee, Cheolui Song & Gilson Khang

  2. Department of Polymer Nano Science & Technology, Jeonbuk National University, Jeonju-si, Jeollabuk-do, Republic of Korea

    Byung Kwan Moon

  3. Department of Orthopedic Surgery, Medical School, Jeonbuk National University, Jeonju-si, Republic of Korea

    Sun-jung Yoon

  4. 3B’s Research Group – Biomaterials, Biodegradables and Biomimetics, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, University of Minho, Guimarães, Portugal

    Nuno M. Neves & Rui L. Reis

  5. ICVS/3B’s – PT Government Associated Laboratory, Braga/Guimarães, Portugal

    Nuno M. Neves & Rui L. Reis

  6. The Discoveries Centre for Regenerative and Precision Medicine, Headquarters at University of Minho, Guimarães, Portugal

    Nuno M. Neves & Rui L. Reis

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  1. Joo Hee Choi
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  2. Wonchan Lee
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  3. Cheolui Song
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  4. Byung Kwan Moon
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  5. Sun-jung Yoon
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  6. Nuno M. Neves
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  7. Rui L. Reis
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  8. Gilson Khang
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Correspondence to Gilson Khang .

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Editors and Affiliations

  1. Institute of Cell & Tissue Engineering and College of Medicine, Catholic University of Korea, Seoul, Korea (Republic of)

    Heung Jae Chun

  2. 3B’s Research Group, I3Bs – Research Institute on Biomaterials, Biodegradables and Biomimetics, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, University of Minho, Guimarães, Portugal

    Rui L. Reis

  3. Department of Industrial Engineering and BIOtech Research Center, University of Trento, Trento, Italy

    Antonella Motta

  4. Department of BIN Convergence Technology, Department of Polymer Nano Science & Technology and Polymer BIN Research Center, Jeonbuk National University, Jeonju, Korea (Republic of)

    Gilson Khang

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Choi, J.H. et al. (2020). Application of Gellan Gum-Based Scaffold for Regenerative Medicine. In: Chun, H.J., Reis, R.L., Motta, A., Khang, G. (eds) Bioinspired Biomaterials. Advances in Experimental Medicine and Biology, vol 1249 . Springer, Singapore. https://doi.org/10.1007/978-981-15-3258-0_2

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