Abstract
The rising popularity and attractive applications of nanotechnologies have impacted all areas of research, including science, agriculture, and health care. Nanoparticles are finding great potential as delivery systems to specific targets in living organisms. Recent advances in food science have revealed that food-derived bioactives significantly influence changes in the genome, epigenome, proteome, and metabolome. This concept is termed “nutrigenomics.” The research in nutrigenomics is fast emerging and explored for the prevention or therapy of various lifestyle-associated disorders such as diabetes, cardiovascular diseases, cancer, and others. The major obstacle in achieving the efficacy from the bioactives is their bioavailability in the plasma and/or at the target site following consumption. The advent of various nanotechnology methods have contributed to promising tools such as nanodelivery systems, including nanocapsules, nanospheres, and biogenic nanoparticles that can enhance the bioavailability of bioactive compounds. This chapter focuses on applications of nanotechnologies in nutrigenomics with a particular focus on their applications for prevention or treatment of certain metabolic disorders.
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Acknowledgments
The authors are thankful to the Director, CSIR-CFTRI, Mysuru, for providing facilities and infrastructure. The corresponding author thanks the Department of Biotechnology and the Science and Engineering Research Board (SERB), Department of Science and Technology, New Delhi, for providing funds in the form of Ramalingaswami fellowship and extramural grant, respectively.
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Janhavi, P., Natasha, J., Neelam, R., Ravindra, P.V. (2020). Nanotechnology and Nutrigenomics. In: Ghorbanpour, M., Bhargava, P., Varma, A., Choudhary, D. (eds) Biogenic Nano-Particles and their Use in Agro-ecosystems. Springer, Singapore. https://doi.org/10.1007/978-981-15-2985-6_19
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DOI: https://doi.org/10.1007/978-981-15-2985-6_19
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