Abstract
Biofilms affect many industries and our daily lives. Their formation and growth processes have common essential factors, but some of their components differ from one environment to another. Biofilms have a negative side in that they cause many problems. However, on a positive note, they provide benefits if used properly and effectively. Therefore, it is very important to be able to control biofilm formation and growth. In this chapter, we describe future trends for the research and applications of biofilms and the types of results that we can expect.
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Xiao, Y., & Zhao, F. (2017). Electrochemical roles of extracellular polymeric substances in biofilms. Current Opinion in Electrochemistry, 4(1), 206–211.
Dheilly, A., Linossier, I., Darchen, A., Hadjiev, D., Corbel, C., & Alonso, V. (2008). Monitoring of microbial adhesion and biofilm growth using electrochemical impedancemetry. Applied Microbiology and Biotechnology, 79(1), 157–164.
Chen, S., Jing, X., Tang, J., Fang, Y., & Zhou, S. (2017). Quorum sensing signals enhance the electrochemical activity and energy recovery of mixed-culture electroactive biofilms. Biosensors and Bioelectronics, 97, 369–376.
Bressel, A., Schultze, J. W., Khan, W., Wolfaardt, G. M., Rohns, H. P., Irmscher, R., et al. (2003). High resolution gravimetric, optical and electrochemical investigations of microbial biofilm formation in aqueous systems. Electrochimica Acta, 48(20–22), 3363–3372.
Dong, Z. H., Shi, W., Ruan, H. M., & Zhang, G. A. (2011). Heterogeneous corrosion of mild steel under SRB-biofilm characterised by electrochemical mapping technique. Corrosion Science, 53(9), 2978–2987.
Beech, I. B., & Sunner, J. (2004). Biocorrosion: Towards understanding interactions between biofilms and metals. Current Opinion in Biotechnology, 15(3), 181–186.
Cordas, C. M., Guerra, L. T., Xavier, C., & Moura, J. J. (2008). Electroactive biofilms of sulphate reducing bacteria. Electrochimica Acta, 54(1), 29–34.
Gamby, J., Pailleret, A., Clodic, C. B., Pradier, C. M., & Tribollet, B. (2008). In situ detection and characterization of potable water biofilms on materials by microscopic, spectroscopic and electrochemistry methods. Electrochimica Acta, 54(1), 66–73.
Tian, M., Kanavillil, N., Davey, L., Leung, K. T., Schraft, H., & Chen, A. (2007). Direct growth of biofilms on an electrode surface and its application in electrochemical biosensoring. Journal of Electroanalytical Chemistry, 611(1–2), 133–139.
Hu, Z., Jin, J., Abruña, H. D., Houston, P. L., Hay, A. G., Ghiorse, W. C., et al. (2007). Spatial distributions of copper in microbial biofilms by scanning electrochemical microscopy. Environmental Science and Technology, 41(3), 936–941.
Liu, B. H., Li, K. L., Kang, K. L., Huang, W. K., & Liao, J. D. (2013). In situ biosensing of the nanomechanical property and electrochemical spectroscopy of Streptococcus mutans-containing biofilms. Journal of Physics. D. Applied Physics, 46(27), 275401.
Kim, T., Kang, J., Lee, J. H., & Yoon, J. (2011). Influence of attached bacteria and biofilm on double-layer capacitance during biofilm monitoring by electrochemical impedance spectroscopy. Water Research, 45(15), 4615–4622.
Grooters, M., Harneit, K., Wöllbrink, M., Sand, W., Stadler, R., & Fürbeth, W. (2007). Novel steel corrosion protection by microbial extracellular polymeric substances (EPS)–biofilm-induced corrosion inhibition. Advanced Materials Research, 20, 375–378. Trans Tech Publications.
Kurissery, S. R., Kanavillil, N., Leung, K. T., Chen, A., Davey, L., & Schraft, H. (2010). Electrochemical and microbiological characterization of paper mill biofilms. Biofouling, 26(7), 799–808.
Kitayama, M., Koga, R., Kasai, T., Kouzuma, A., & Watanabe, K. (2017). Structures, compositions, and activities of live Shewanella biofilms formed on graphite electrodes in electrochemical flow cells. Applied and Environmental Microbiology, 83(17), e00903–17.
Beech, I. B. (2004). Corrosion of technical materials in the presence of biofilms: Current understanding and state-of-the art methods of study. International Biodeterioration and Biodegradation, 53(3), 177–183.
Fang, H. H., Xu, L. C., & Chan, K. Y. (2002). Effects of toxic metals and chemicals on biofilm and biocorrosion. Water Research, 36(19), 4709–4716.
Cao, B., Shi, L., Brown, R. N., Xiong, Y., Fredrickson, J. K., Romine, M. F., et al. (2011). Extracellular polymeric substances from Shewanella sp. HRCR1 biofilms: Characterization by infrared spectroscopy and proteomics. Environmental Microbiology, 13(4), 1018–1031.
Dong, Z. H., Liu, T., & Liu, H. F. (2011). Influence of EPS isolated from thermophilic sulphate-reducing bacteria on carbon steel corrosion. Biofouling, 27(5), 487–495.
Chen, S., Wang, P., & Zhang, D. (2014). Corrosion behavior of copper under biofilm of sulfate-reducing bacteria. Corrosion Science, 87, 407–415.
Jang, A., Kim, S. M., Kim, S. Y., Lee, S. G., & Kim, I. S. (2001). Effect of heavy metals (Cu, Pb, and Ni) on the compositions of EPS in biofilms. Water Science and Technology, 43(6), 41–48.
Flemming, H.-C. (1995). Sorption sites in biofilms. Water Science and Technology, 32(8), 27–33.
Neu, T. R., & Lawrence, J. R. (1999). In Situ characterization of extracellular polymeric substances (EPS) in biofilm systems. In J. Wingender, T. R. Neu, & H. C. Flemming (Eds.), Microbial extracellular polymeric substances. Berlin, Heidelberg: Springer.
McLamore, E. S., Porterfield, D. M., & Banks, M. K. (2009). Non-invasive self- referencing electrochemical sensors for quantifying real-time biofilm analyte flux. Biotechnology and Bioengineering, 102(3), 791–799.
Waszczuk, K., Gula, G., Swiatkowski, M., Olszewski, J., Herwich, W., Drulis-Kawa, Z., et al. (2012). Evaluation of Pseudomonas aeruginosa biofilm formation using piezoelectric tuning fork mass sensors. Sensors and Actuators B: Chemical, 170, 7–12.
Sahoo, P. K., Janissen, R., Monteiro, M. P., Cavalli, A., Murillo, D. M., Merfa, M. V., et al. (2016). Nanowire arrays as cell force sensors to investigate adhesin- enhanced holdfast of single cell bacteria and biofilm stability. Nano Letters, 16(7), 4656–4664.
Zheng, L. Y., Congdon, R. B., Sadik, O. A., Marques, C. N., Davies, D. G., Sammakia, B. G., et al. (2013). Electrochemical measurements of biofilm development using polypyrrole enhanced flexible sensors. Sensors and Actuators B: Chemical, 182, 725–732.
Mollica, A., & Cristiani, P. (2003). On-line biofilm monitoring by BIOX electrochemical probe. Water Science and Technology, 47(5), 45–49.
Liu, J., & Mattiasson, B. (2002). Microbial BOD sensors for wastewater analysis. Water Research, 36(15), 3786–3802.
Marcus, I. M., Herzberg, M., Walker, S. L., & Freger, V. (2012). Pseudomonas aeruginosa attachment on QCM-D sensors: The role of cell and surface hydrophobicities. Langmuir, 28(15), 6396–6402.
Tribollet, B. (2003). Electrochemical sensors for biofilm and biocorrosion. Materials and Corrosion, 54(7), 527–534.
Piasecki, T., Guła, G., Nitsch, K., Waszczuk, K., Drulis-Kawa, Z., & Gotszalk, T. (2013). Evaluation of Pseudomonas aeruginosa biofilm formation using quartz tuning forks as impedance sensors. Sensors and Actuators B: Chemical, 189, 60–65.
Waszczuk, K., Gula, G., Swiatkowski, M., Olszewski, J., Drulis-Kawa, Z., Gutowicz, J., et al. (2010). Evaluation of Pseudomonas aeruginosa biofilm formation using piezoelectric tuning forks mass sensors. Procedia Engineering, 5, 820–823.
Lewandowski, Z., & Beyenal, H. (2014). Fundamentals of biofilm research (2nd ed.). Boca Raton, London, New York: CRC Press.
Beyenal, H., & Babauta, J. T. (Eds.). (2015). Biofilms in bioelectrochemical systems. Hoboken, New Jersey: Wiley.
Pringault, O., Epping, E., Guyoneaud, R., Khalili, A., & KuÈhl, M. (1999). Dynamics of anoxygenic photosynthesis in an experimental green sulphur bacteria biofilm. Environmental Microbiology, 1(4), 295–305.
Lee, J. H., Myers, R. R., Jang, A., Bhadri, P., Beyette, F., Timmons, W. & Papaurh:tsky, I. (October, 2004). Potentiometric microelectrode sensors for in situ environmental monitoring. In SENSORS, 2004 IEEE (pp. 361–364). IEEE.
Atta, N. F., Galal, A., Mark, H. B., Jr., Yu, T., & Bishop, P. L. (1998). Conducting polymer ion sensor electrodes–III. Potentiometric sulfide ion selective electrode. Talanta, 47(4), 987–999.
Vonau, W., Gabel, J., & Jahn, H. (2005). Potentiometric all solid-state pH glass sensors. Electrochimica Acta, 50(25–26), 4981–4987.
Gieseke, A. R. M. I. N., & de Beer, D. I. R. K. (2004). Use of microelectrodes to measure in situ microbial activities in biofilms, sediments, and microbial mats. Molecular Microbial Ecology Manual, 2, 1581–1612.
Pires, L., Sachsenheimer, K., Kleintschek, T., Waldbaur, A., Schwartz, T., & Rapp, B. E. (2013). Online monitoring of biofilm growth and activity using a combined multi-channel impedimetric and amperometric sensor. Biosensors and Bioelectronics, 47, 157–163.
Quintana, J. C., Idrissi, L., Palleschi, G., Albertano, P., Amine, A., El Rhazi, M., et al. (2004). Investigation of amperometric detection of phosphate: Application in seawater and cyanobacterial biofilm samples. Talanta, 63(3), 567–574.
Loret, J. F., Robert, S., Thomas, V., Levi, Y., Cooper, A. J., & McCoy, W. F. (2005). Comparison of disinfectants for biofilm, protozoa and Legionella control. Journal of Water and Health, 3(4), 423–433.
Dulon, S., Parot, S., Delia, M. L., & Bergel, A. (2007). Electroactive biofilms: New means for electrochemistry. Journal of applied electrochemistry, 37(1), 173–179.
Commault, A. S., Lear, G., Bouvier, S., Feiler, L., Karacs, J., & Weld, R. J. (2016). Geobacter-dominated biofilms used as amperometric BOD sensors. Biochemical Engineering Journal, 109, 88–95.
Paredes, J., Becerro, S., Arizti, F., Aguinaga, A., Del Pozo, J. L., & Arana, S. (2012). Real time monitoring of the impedance characteristics of Staphylococcal bacterial biofilm cultures with a modified CDC reactor system. Biosensors and Bioelectronics, 38(1), 226–232.
Muñoz-Berbel, X., Muñoz, F. J., Vigués, N., & Mas, J. (2006). On-chip impedance measurements to monitor biofilm formation in the drinking water distribution network. Sensors and Actuators B: Chemical, 118(1–2), 129–134.
Paredes, J., Becerro, S., Arizti, F., Aguinaga, A., Del Pozo, J. L., & Arana, S. (2013). Interdigitated microelectrode biosensor for bacterial biofilm growth monitoring by impedance spectroscopy technique in 96-well microtiter plates. Sensors and Actuators B: Chemical, 178, 663–670.
Zikmund, A., Ripka, P., Krasny, L., Judl, T., & Jahoda, D. (October, 2010). Biofilm detection by the impedance method. In 2010 3rd International Conference on Biomedical Engineering and Informatics (Vol. 4, pp. 1432–1434). IEEE.
Chabowski, K., Junka, A. F., Szymczyk, P., Piasecki, T., Sierakowski, A., Mączyńska, B. E. A. T. A., et al. (2015). The Application of impedance microsensors for real-time analysis of Pseudomonas aeruginosa biofilm formation. Polish Journal of Microbiology, 64, 115–120.
Paredes, J., Becerro, S., & Arana, S. (2014). Label-free interdigitated microelectrode based biosensors for bacterial biofilm growth monitoring using Petri dishes. Journal of Microbiological Methods, 100, 77–83.
Kanematsu, H., Satoh, M., Shindo, K., Barry, D. M., Hirai, N., Ogawa, A., et al. (2017). Biofilm formation behaviors on graphene by E. coli and S. epidermidis. ECS Transactions, 80(10), 1167–1175. https://doi.org/10.1149/08010.1167ecst.
Kanematsu, H., Shindo, K., Barry, D. M., Hirai, N., Ogawa, A., Kuroda, D., et al. (2018). Electrochemical responses of graphene with biofilm formation on various metallic substrates by using laboratory biofilm reactors. ECS Transactions, 85(13), 491–498. https://doi.org/10.1149/08513.0491ecst.
Kanematsu, H., Nakagawa, R., Barry, D. M., Sano, K., Ishihara, M., Ban, M., Kuroda, D. (2019). Interaction between graphene surfaces and extracellular polymeric substances of biofilms. Paper presented at the Contributed Papers from Materials Science and Technology 2019 (MS and T19).
Kanematsu, H., Nakagawa, R., Sano, K., Barry, D. M., Ogawa, A., Hira, N., et al. (2019). Graphene dispersed silane compound used as a coating to sense immunity from biofilm formatiom. Medical Devices and Sensors, 1, 1–16. https://doi.org/10.1002/mds3.10043.
Connell, J. L., Kim, J., Shear, J. B., Bard, A. J., & Whiteley, M. (2014). Real-time monitoring of quorum sensing in 3D-printed bacterial aggregates using scanning electrochemical microscopy. Proceedings of the National Academy of Sciences, 111(51), 18255–18260.
Bellin, D. L., Sakhtah, H., Rosenstein, J. K., Levine, P. M., Thimot, J., Emmett, K., et al. (2014). Integrated circuit-based electrochemical sensor for spatially resolved detection of redox-active metabolites in biofilms. Nature Communications, 5, 3256.
Hassan, R. Y., El-Attar, R. O., Hassan, H. N., Ahmed, M. A., & Khaled, E. (2017). Carbon nanotube-based electrochemical biosensors for determination of Candida albicans’s quorum sensing molecule. Sensors and Actuators B: Chemical, 244, 565–570.
Lear, G., & Lewis, G. D. (Eds.) (2012). Microbial biofilms: Current research and applications. Horizon Scientific Press.
Dietrich, L. E., Price-Whelan, A., Petersen, A., Whiteley, M., & Newman, D. K. (2006). The phenazine pyocyanin is a terminal signaling factor in the quorum sensing network of Pseudomonas aeruginosa. Molecular Microbiology, 61(5), 1308–1321.
Bellin, D. L., Sakhtah, H., Zhang, Y., Price-Whelan, A., Dietrich, L. E., & Shepard, K. L. (2016). Electrochemical camera chip for simultaneous imaging of multiple metabolites in biofilms. Nature Communications, 7, 10535.
Bukelman, O., Amara, N., Mashiach, R., Krief, P., Meijler, M. M., & Alfonta, L. (2009). Electrochemical analysis of quorum sensing inhibition. Chemical Communications, 20, 2836–2838.
Bodelón, G., Montes-García, V., López-Puente, V., Hill, E. H., Hamon, C., Sanz- Ortiz, M. N., et al. (2016). Detection and imaging of quorum sensing in Pseudomonas aeruginosa biofilm communities by surface-enhanced resonance Raman scattering. Nature Materials, 15(11), 1203.
Geske, G. D., Wezeman, R. J., Siegel, A. P., & Blackwell, H. E. (2005). Small molecule inhibitors of bacterial quorum sensing and biofilm formation. Journal of the American Chemical Society, 127(37), 12762–12763.
De Kievit, T. R. (2009). Quorum sensing in Pseudomonas aeruginosa biofilms. Environmental Microbiology, 11(2), 279–288.
Virdis, B., Harnisch, F., Batstone, D. J., Rabaey, K., & Donose, B. C. (2012). Non-invasive characterization of electrochemically active microbial biofilms using confocal Raman microscopy. Energy and Environmental Science, 5(5), 7017–7024.
Liu, X., Ramsey, M. M., Chen, X., Koley, D., Whiteley, M., & Bard, A. J. (2011). Real-time mapping of a hydrogen peroxide concentration profile across a polymicrobial bacterial biofilm using scanning electrochemical microscopy. Proceedings of the National Academy of Sciences, 108(7), 2668–2673.
Abucayon, E., Ke, N., Cornut, R., Patelunas, A., Miller, D., Nishiguchi, M. K., et al. (2013). Investigating catalase activity through hydrogen peroxide decomposition by bacteria biofilms in real time using scanning electrochemical microscopy. Analytical Chemistry, 86(1), 498–505.
Torres, C. I., Krajmalnik-Brown, R., Parameswaran, P., Marcus, A. K., Wanger, G., Gorby, Y. A., et al. (2009). Selecting anode-respiring bacteria based on anode potential: Phylogenetic, electrochemical, and microscopic characterization. Environmental Science and Technology, 43(24), 9519–9524.
Xia, F., Beyenal, H., & Lewandowski, Z. (1998). An electrochemical technique to measure local flow velocity in biofilms. Water Research, 32(12), 3631–3636.
Khan, M. M., Ansari, S. A., Lee, J. H., Lee, J., & Cho, M. H. (2013). Mixed culture electrochemically active biofilms and their microscopic and spectroelectrochemical studies. ACS Sustainable Chemistry and Engineering, 2(3), 423–432.
Kanematsu, H., Umeki, S., Hirai, N., Miura, Y., Wada, N., Kogo, T., et al. (2016). Verification of effect of alternative electromagnetic treatment on control of biofilm and scale formation by a new laboratory biofilm reactor. Ceramic Transactions, 259, 199–212. https://doi.org/10.1002/9781119323303.
Kanematsu, H., Umeki, S., Ogawa, A., Hirai, N., Kogo, T., & Tohji, K. (2016). The cleaning effect on metallic materials under a weak alternating electromagnetic field and biofilm. Paper presented at the Ninth Pacific Rim International Conference on Advanced Materials and Processing (PRICM9), Kyoto, Japan.
Kanematsu, H., Katsuragawa, T., Barry, D. M., Yokoi, K., Umeki, S., Miura, H., et al. (2019). Biofilm formation behaviors formed by E.coli under weak alternating electromagnetic fields. Ceramic Transactions (Advances in Ceramics for Environmental, Functional Structural, and Energy Applications II), 266, 195–208.
Kanematsu, H., Miura, H., Barry, D. M., & Zimmermann, S. (2019). Effect of alternating electromagnetic field on extracellular polymeric substances derived from biofilms and its mechanism. Paper presented at the Contributed Papers from Materials Science and Technology 2019 (MS&T19), Oregon Convention Center in Portland, Oregon, USA.
McLeod, B. R., Fortun, S., Costerton, J. W., & Stewart, P. S. (1999). [49] Enhanced bacterial biofilm control using electromagnetic fields in combination with antibiotics. In Methods in enzymology (Vol. 310, pp. 656–670). Academic Press.
Pickering, S. A. W., Bayston, R., & Scammell, B. E. (2003). Electromagnetic augmentation of antibiotic efficacy in infection of orthopaedic implants. The Journal of Bone and Joint Surgery. British Volume, 85(4), 588–593.
Di Campli, E., Di Bartolomeo, S., Grande, R., Di Giulio, M., & Cellini, L. (2010). Effects of extremely low-frequency electromagnetic fields on Helicobacter pylori biofilm. Current Microbiology, 60(6), 412–418.
Caubet, R., Pedarros-Caubet, F., Chu, M., Freye, E., de Belem Rodrigues, M., Moreau, J. M., et al. (2004). A radio frequency electric current enhances antibiotic efficacy against bacterial biofilms. Antimicrobial Agents and Chemotherapy, 48(12), 4662–4664.
Ehrlich, G. D., Stoodley, P., Kathju, S., Zhao, Y., McLeod, B. R., Balaban, N., & Post, J. C. (2005). Engineering approaches for the detection and control of orthopedic biofilm infections. Clinical Orthopedics and Related Research, (437), 59.
Del Pozo, J. L., Rouse, M. S., & Patel, R. (2008). Bioelectric effect and bacterial biofilms. A systematic review. The International Journal of Artificial Organs, 31(9), 786–795.
Torgomyan, H., & Trchounian, A. (2013). Bactericidal effects of low-intensity extremely high frequency electromagnetic field: An overview with phenomenon, mechanisms, targets and consequences. Critical Reviews in Microbiology, 39(1), 102–111.
Obermeier, A., Matl, F. D., Friess, W., & Stemberger, A. (2009). Growth inhibition of Staphylococcus aureus induced by low frequency electric and electromagnetic fields. Bioelectromagnetics: Journal of the Bioelectromagnetics Society, The Society for Physical Regulation in Biology and Medicine, The European Bioelectromagnetics Association, 30(4), 270–279.
Matl, F. D., Obermeier, A., Zlotnyk, J., Friess, W., Stemberger, A., & Burgkart, R. (2011). Augmentation of antibiotic activity by low-frequency electric and electromagnetic fields examining Staphylococcus aureus in broth media. Bioelectromagnetics, 32(5), 367–377.
Sureshkumar, A., Sankar, R., Mandal, M., & Neogi, S. (2010). Effective bacterial inactivation using low temperature radio frequency plasma. International Journal of Pharmaceutics, 396(1–2), 17–22.
Takashima, S., Gabriel, C., Sheppard, R. J., & Grant, E. H. (1984). Dielectric behavior of DNA solution at radio and microwave frequencies (at 20 °C). Biophysical Journal, 46(1), 29–34.
Wei, M. Q., Mengesha, A., Good, D., & Anné, J. (2008). Bacterial targeted tumour therapy-dawn of a new era. Cancer Letters, 259(1), 16–27.
Privat-Maldonado, A., O’Connell, D., Welch, E., Vann, R., & Van Der Woude, M. W. (2016). Spatial dependence of DNA damage in bacteria due to low-temperature plasma application as assessed at the single cell level. Scientific Reports, 6, 35646.
Xie, T. D., & Tsong, T. Y. (1990). Study of mechanisms of electric field-induced DNA transfection. II. Transfection by low-amplitude, low-frequency alternating electric fields. Biophysical Journal, 58(4), 897–903.
Sansonetti, P., Boileau, C., & D’hauteville, H. (1989). U.S. Patent No. 4,816,389. Washington, DC: U.S. Patent and Trademark Office.
Belloni, F., Nassisi, V., Alifano, P., Monaco, C., Talà, A., Tredici, M., et al. (2005). A suitable plane transmission line at 900 MHz rf fields for E. coli DNA studies. Review of Scientific Instruments, 76(5), 054302.
Tyurin, M., Padda, R., Huang, K. X., Wardwell, S., Caprette, D., & Bennett, G. N. (2000). Electrotransformation of Clostridium acetobutylicum ATCC 824 using high- voltage radio frequency modulated square pulses. Journal of Applied Microbiology, 88(2), 220–227.
Raffa, V., Vittorio, O., Costa, M., Ziaei, A., Nitodas, S., Riggio, C., et al. (2012). Multiwalled carbon nanotube antennas induce effective plasmid dna transfection of bacterial cells. Journal of Nanoneuroscience, 2(1), 56–62.
Sharma, A., Pruden, A., Yu, Z., & Collins, G. J. (2005). Bacterial inactivation in open air by the afterglow plume emitted from a grounded hollow slot electrode. Environmental Science and Technology, 39(1), 339–344.
De Ninno, Antonella, & Pregnolato, Massimo. (2017). Electromagnetic homeostasis and the role of low-amplitude electromagnetic fields on life organization. Electromagnetic Biology and Medicine, 36(2), 115–122.
Trushin, M. V. (2003). The possible role of electromagnetic fields in bacterial communication. Journal of Microbiology, Immunology, and Infection, 36(3), 153–160.
Karaguler, T., Kahraman, H., & Tuter, M. (2017). Analyzing effects of ELF electromagnetic fields on removing bacterial biofilm. Biocybernetics and Biomedical Engineering, 37(2), 336–340.
Brkovic, S., Postic, S., & Ilic, D. (2015). Influence of the magnetic field on microorganisms in the oral cavity. Journal of Applied Oral Science, 23(2), 179–186.
Lawrence, R. N., Dunn, W. R., Bycroft, B., Camara, M., Chhabra, S. R., Williams, P., et al. (1999). The Pseudomonas aeruginosa quorum-sensing signal molecule, N (3-oxododecanoyl)-l-homoserine lactone, inhibits porcine arterial smooth muscle contraction. British Journal of Pharmacology, 128(4), 845–848.
Zhang, L. H., & Dong, Y. H. (2004). Quorum sensing and signal interference: Diverse implications. Molecular Microbiology, 53(6), 1563–1571.
Russo, G., & Slotine, J. J. E. (2010). Global convergence of quorum-sensing networks. Physical Review E, 82(4), 041919.
Adey, W. R. (2003). Evidence for non-thermal electromagnetic bioeffects: Potential health risks in evolving low-frequency and microwave environments. Electromagnetic environments and health in buildings.
Del Pozo, J. L., & Patel, R. (2007). The challenge of treating biofilm-associated bacterial infections. Clinical Pharmacology and Therapeutics, 82(2), 204–209.
Ehrlich, G. D., Stoodley, P., Kathju, S., Zhao, Y., McLeod, B. R., Balaban, N., et al. (2005). Engineering approaches for the detection and control of orthopedic biofilm infections. Clinical Orthopaedics and Related Research, 437, 59.
Schnabel, W. (2014). Polymers and electromagnetic radiation—fundamentals and practical application. Weinheim, Germany: Wiley-VCH.
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Kanematsu, H., Barry, D.M. (2020). Biofilm Control and Thoughts for the Future. In: Formation and Control of Biofilm in Various Environments. Springer, Singapore. https://doi.org/10.1007/978-981-15-2240-6_10
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