Abstract
The phytochemical investigation of the roots of Aegle marmelos revealed the presence of secondary metabolites like alkaloids, anthraquinones, cardiac glycosides, flavonoids, glycosides, phenols, saponins, steroids, tannins, terpenoids, amino acids, and carbohydrates. The antimicrobial activity and minimum inhibition concentration values were determined for these phytochemical constituents as crude extracts using the agar well diffusion and twofold serial dilution methods, respectively. The results indicated that Bacillus subtilis was the most susceptible bacterium with high inhibition zones for the methanol and chloroform extracts of 31 and 26 mm, respectively. The minimum inhibitory concentration values indicated that extracts possess good phytochemicals with significant minimum inhibitory concentration value against Bacillus subtilis, Klebsiella pneumoniae, and Staphylococcus aureus at 31.2 μg/ml concentration. The extracts showed marked antimicrobial activity against both bacteria and fungi. Among the bacterial strains, Gram-positive bacteria were more susceptible than the Gram-negative. All the tested 12 microorganisms showed dose-dependent susceptibility towards the phytochemicals present in the solvent as well as aqueous crude extracts. The present study suggests that Aegle marmelos roots possess potent antimicrobial activity and can be a good source for the development of new antibiotics.
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Owk, A.K., Lagudu, M.N. (2020). Aegle marmelos (Rutaceae): Evaluation of Root Phytochemical Constituents for Antimicrobial Activity. In: Khasim, S.M., Long, C., Thammasiri, K., Lutken, H. (eds) Medicinal Plants: Biodiversity, Sustainable Utilization and Conservation. Springer, Singapore. https://doi.org/10.1007/978-981-15-1636-8_34
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DOI: https://doi.org/10.1007/978-981-15-1636-8_34
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