Abstract
Tannins are high-molecular-weight and water-soluble naturally occurring polyphenols that are widely distributed in many species of plants at higher levels. Syzygium samarangense (Blume) Merr. & L.M. Perry is a famous deciduous tree belonging to Myrtaceae family, which is being cultivated in India mainly for its edible fruits. It is also well known by other names, e.g. java apple and water apple. Based on literature survey, we found that S. samarangense is having a rich content of tannins. In this study, we have isolated two compounds, i.e. methyl gallate and 3-methoxy ellagic acid, from acetone extract of stem bark of S. samarangense by using two different methods; and further, these fractions were individually separated and purified by using RP-HPLC. The structures of these purified compounds were confirmed by using different spectral techniques.
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References
Akiyama H, Kazuyasu F, Yamasaki O, Oono T, Iwatsuki K (2001) Antibacterial action of several tannins against Staphylococcus aureus. J Antimicrob Chemother 48:487–491
Arbenz A, Avérous L (2015) Chemical modification of tannins to elaborate aromatic biobased macromolecular architectures. Green Chem 17:2626–2646
Bajec MR, Pickering GJ (2008) Astringency: mechanisms and perception. Crit Rev Food Sci Nutr 48:858–875
Bate-Smith EC, Swain T (1962) In: Mason HS, Florkin M (eds) Comparative biochemistry, vol 3. Academic Press, New York, p 764
Funatogawa K, Hayashi S, Shimomura H, Yoshida T, Hatano T, Ito H (2004) Antibacterial activity of hydrolysable tannins derived from medicinal plants against Helicobacter pylori. Microbiol Immunol 48(4):251–261
Ghayur MN, Gilani AH, Khan A, Amor EC, Villaseñor IM, Choudhary MI (2006) Presence of calcium antagonist activity explains the use of Syzygium samarangense in diarrhea. Phytother Res 20(1):49–52
Haslam E (1989) Plant polyphenols-vegetable tannins revisited-chemistry and pharmacology of natural products. Cambridge University Press, Cambridge, p 165
Jain P, Jain S, Pareek A, Sharma S (2013) A comprehensive study on the natural plant phenols: perception to current scenario. Bull Pharm Res 3(2):90–106
Kesava Rao B, Asha Bhanu P, Usha Rani G (2016) Atomic absorption spectral analysis & pharmacological properties of multi-metals isolated from the stem bark of syzygium samarangense (myrtaceae family). Int J Rec Sci Res 7(4):10633–10635
Khanbabaee K, van Ree T (2001) Tannins: classification and definition. Nat Prod Rep 18:641–649
Kuo YC, Yang LM, Lin LC (2004) Isolation and immunomodulatory effect of flavonoids from Syzygium samarangense. Planta Med 70(12):1237–1239
Landete JM (2011) Ellagitannins, ellagic acid and their derived metabolites a review about source, metabolism, functions and health. Food Res Int 44(5):1150–1160
Lin LU, Shu-wen L, Shi-bo J, Shu-guang W (2004) Tannin inhibits HIV-1 entry by targeting gp 41. Acta Pharm Sin 25(2):213–218
Morton J (1987) Fruits of warm climates. Julia F. Morton Publication, Miami, pp 381–382
Nair AGRS, Krishnan S, Ravikrishna C, Madhusudanan KP (1999) New and rare flavonol glycosides from leaves of Syzygium samarangense. Fitoterapia 70:148–151
Nonaka G-I, Aiko Y, Aritake K, Nishioka I (1992) Tannins and related compounds: CXIX. Samarangenins A and B, novel proanthocyanidins with doubly bonded structures from Syzygium samarangense and Syzygium aqueum. Chem Pharm Bull 40(10):2671–2673
Okuda T (2005) Systematics and health effects of chemically distinct tannins in medicinal plants. Phytochemistry 66:2012–2031
Porter LJ (1989) In: Dey PM, Harborne JB (eds) Methods in plant biochemistry—plant phenolics series, vol 1. Academic Press, London, p 389
Raga DD, Cheng CL, Lee KC, Olaziman WZ, De Guzman VJ, Shen CC, Franco FC Jr, Ragasa CY (2011) Bioactivities of triterpenes and a sterol from Syzygium samarangense. Z Nat C 66(5–6):235–244
Schofield P, Mbugua DM, Pell AN (2001) Analysis of condensed tannins a review. Anim Feed Sci Technol 91:21–40
Soubir T (2007) Antioxidant activities of some local bangladeshi fruits (Artocarpus heterophyllus, Annona squamosa, Terminalia bellirica, Syzygium samarangense, Averrhoa carambola and Olea europa). Sheng Wu Gong Cheng XueBao 23(2):257–261
Srivastava R, Shaw AK, Kulshreshtha DK (1995) Triterpenoids and chalcone from Syzygium samarangense. Phytochemistry 38(3):687–689
Tabak LA (1995) In defense of the oral cavity: structure, biosynthesis & function of salivary mucins. Annu Rev Physiol 57(1):547–564
Acknowledgements
We are very much thankful to all the faculty members of the Department of Chemistry and to the administration of Acharya Nagarjuna University, for their constant encouragement. P. Asha Bhanu is very much thankful to University Grants Commission for sanctioning her Rajiv Gandhi National Fellowship for the year 2015–2017.
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Bhanu, P.A., Mohan Krishna Reddy, M., Sadhana Reddy, N., Kesava Rao, B. (2020). Isolation and Characterization of Pharmacologically Active Tannins from Stem Bark of Syzygium samarangense. In: Khasim, S.M., Long, C., Thammasiri, K., Lutken, H. (eds) Medicinal Plants: Biodiversity, Sustainable Utilization and Conservation. Springer, Singapore. https://doi.org/10.1007/978-981-15-1636-8_32
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