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The Role of Diverse Nanoparticles in Oxidative Stress: In Vitro and In Vivo Studies

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Role of Oxidative Stress in Pathophysiology of Diseases

Abstract

Nanoparticles are a very advanced area of nanotechnology and play an important role in medical sciences and technology. Nanoparticles such as polymer and metal nanoparticles are widely used in applications for antioxidant activity. Nonenzymatic antioxidant assays using free radical–scavenging activity of nanoparticles have been investigated using different methods such as 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) assays, nitric oxide radical inhibition assays, superoxide anion–scavenging activity, reducing power, determination of total phenolic compounds and hydroxyl radical–scavenging assays. The investigated metal nanoparticle included gold, zinc oxide, copper, silver, zirconium oxide and selenium, and the polymer nanoparticles include chitosan and silica.

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Authors and Affiliations

  1. Department of Pharmacology, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Science (SIMATS), Saveetha University, Chennai, Tamil Nadu, India

    Shanmugam Rajeshkumar, Devaraj Ezhilarasan & Thangavelu Lakshmi

  2. Dental Research Cell (DRC-BRULAC), Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Science (SIMATS), Saveetha University, Chennai, Tamil Nadu, India

    Durairaj Sekar

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  1. Shanmugam Rajeshkumar
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  2. Durairaj Sekar
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  3. Devaraj Ezhilarasan
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  4. Thangavelu Lakshmi
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Editors and Affiliations

  1. Department of Biochemistry, Central University of Haryana, Mahendergarh, Haryana, India

    Pawan K. Maurya

  2. Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Sydney, NSW, Australia

    Kamal Dua

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Rajeshkumar, S., Sekar, D., Ezhilarasan, D., Lakshmi, T. (2020). The Role of Diverse Nanoparticles in Oxidative Stress: In Vitro and In Vivo Studies. In: Maurya, P., Dua, K. (eds) Role of Oxidative Stress in Pathophysiology of Diseases. Springer, Singapore. https://doi.org/10.1007/978-981-15-1568-2_3

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