Abstract
Aging is manifested within an individual due to cognitive dysfunction, oxidative stress, decline in the volumes and functions of certain areas of brain, central neurotransmitter deficits, and undernutrition/malnutrition. Progressive dysfunction of the body’s homeostasis and increased susceptibility to stress and diseases are manifested with advancing age. Aging is heritable either due to allelic variation or due to polymorphism of genes. Aging alters the function of cells and various organs of the body. Despite numerous theories (cellular senescence theory, molecular inflammatory theory, mitochondrial aging theory, glycation theory, shorter telomeres theory, etc.) have been proposed, the mechanism of decline of progressive physiological functions with advancing age is poorly understood. Nutritional interventions will help to age successfully with higher functional ability in all aspects (physical, mental, and social), even at old age.
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Further Reading
Carroll MA (2018) Cognitive aging and changes in brain morphology: a narrative review. Top Geriatr Rehabil 34(1):1–7
Kregel KC, Zhang HJ (2007) An integrated view of oxidative stress in aging: basic mechanism, functional effects, and pathological considerations. Am J Physiol Regul Integr Comp Physiol 292:R18–R36
Poscia A et al (2018) Effectiveness of nutritional interventions addressed to elderly persons: umbrella systematic review with meta-analysis. Eur J Pub Health 28(2):275–283
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Chakrabarty, K., Chakrabarty, A.S. (2019). An Integrated View of Cognition, Oxidative Stress, Brain Functions, and Nutritional Interventions in Aging. In: Textbook of Nutrition in Health and Disease. Springer, Singapore. https://doi.org/10.1007/978-981-15-0962-9_15
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DOI: https://doi.org/10.1007/978-981-15-0962-9_15
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