Abstract
Blood transfusion is a common practice in the ICU with an estimate of 40% patients having transfusion. It is generally safe but occasionally may lead to minor or life-threatening consequences if attention to details and protocols is not met during transfusion.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Suggested Reading
BCSH. Guidelines for management of massive blood loss. Br J Haematol. 2006;135:634–41. It is an evidence-based guideline on management of massive blood loss
Cooper DJ, McQuilten ZK. Age of red cells for transfusion and outcomes in critically Ill adults. N Engl J Med. 2017;377(19):1858–67. Critically ill adults received randomly either the freshest available, compatible, allogeneic red cells (short-term storage group) or standard-issue (oldest available), compatible, allogeneic red cells (long-term storage group). The primary outcome was 90-day mortality. Among the 2457 patients in the short-term storage group, the mean storage duration was 11.8 days. Among the 2462 patients in the long-term storage group, the mean storage duration was 22.4 days. At 90 days, there were 610 deaths (24.8%) in the short-term storage group and 594 (24.1%) in the long-term storage group P=0.57). The age of transfused red cells did not affect 90-day mortality among critically ill adults
Klein HG, Spahn DR. Series on transfusion medicine. Lancet. 2007;370:415–48. An excellent review on red cell transfusion, platelet transfusion, and coagulation factor concentrates
Lacroix J, Hébert PC. Age of transfused blood in critically ill adults. N Engl J Med. 2015;372(15):1410–8. 1211 patients were randomly assigned to receive fresh red cells and 1219 patients were assigned to receive standard-issue red cells Red cells were stored a mean (±SD) of 6.1±4.9 days in the fresh-blood group as compared with 22.0±8.4 days in the standard-blood group (P<0.001). At 90 days, 448 patients (37.0%) in the fresh-blood group and 430 patients (35.3%) in the standard-blood group had died which was not significant. Transfusion of fresh red cells, as compared with standard-issue red cells, did not decrease the 90-day mortality among critically ill adults
Napolitano LM, Kurek S. American College of Critical Care Medicine of the Society of Critical Care Medicine, Eastern Association for the Surgery of Trauma Practice Management Workgroup. Clinical practice guideline: red blood cell transfusion in adult trauma and critical care. Crit Care Med. 2009;37:3124–57. These are evidence-based guidelines on the use of RBC transfusions in adult trauma and critical care endorsed by SCCM
Tomaselli GF, Mahaffey KW, Cuker A, Dobesh PP, Doherty JU, Eikelboom JW, Florido R, Hucker W, Mehran R, Messé SR, Pollack CV Jr, Rodriguez F, Sarode R, Siegal D, Wiggins BS. 2017 ACC Expert Consensus Decision Pathway on Management of Bleeding in Patients on Oral Anticoagulants: A Report of the American College of Cardiology Task Force on Expert Consensus Decision Pathways. J Am Coll Cardiol. 2017;70(24):3042–67.
Yazer MH, et al. How do I implement a whole blood program for massively bleeding patients? Transfusion. 2018;58(3):622–8. A review article on practical implementation of blood transfusion in massive bleeding
Websites
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2020 Springer Nature Singapore Pte Ltd.
About this chapter
Cite this chapter
Amin, N., Patil, V. (2020). Transfusion Practices and Complications. In: Chawla, R., Todi, S. (eds) ICU Protocols. Springer, Singapore. https://doi.org/10.1007/978-981-15-0902-5_7
Download citation
DOI: https://doi.org/10.1007/978-981-15-0902-5_7
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-15-0901-8
Online ISBN: 978-981-15-0902-5
eBook Packages: MedicineMedicine (R0)