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Drug-Induced and Exogenous Hypertension

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Abstract

Numerous substances including prescription medications, over-the-counter medications, herbals, and other substances have been reported to be associated with the development of hypertension. The commonly used drugs such as nonsteroidal anti-inflammatory drugs or glucocorticoids may bring about sufficient elevation in blood pressure (BP) to raise the suspicion of secondary hypertension and can interfere with BP-lowering effects of antihypertensive agents in treated hypertensive patients and worsening BP control in known hypertensive patients. In clinical assessment of hypertension, careful collection of drug and food substance history is important when a diagnosis for secondary hypertension is considered, with close attention paid to not only prescription medications but also over-the-counter substances, illicit drugs, herbal products, and food substances, which may also affect BP, changes in BP that occur because of drugs, and other agents resulted from drug–drug or drug–food interactions. When feasible, drugs or food substances associated with increased BP should be reduced or discontinued, and alternative agents should be used [1, 2].

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Li, N., Heizhati, M., Lu, S., Aierken, N. (2020). Drug-Induced and Exogenous Hypertension. In: Li, N. (eds) Secondary Hypertension. Springer, Singapore. https://doi.org/10.1007/978-981-15-0591-1_20

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