Abstract
Malaria being prevalent disease in urban areas, demands its accurate and fast diagnosis. Due to malaria infection in human being, the erythrocyte features got distorted. To diagnose these, various techniques have been developed, i.e., machine learning-based system, rapid diagnostic test, quantitative buffy coat, etc. In machine learning, the system performance depends on the feature set and classifier model. In this paper, the analysis of the importance of the feature set on malaria-infected erythrocyte classification has been performed. Further, a classifier model based on ANN-GA has been developed to classify the erythrocyte. The process consists of illumination correction, erythrocyte segmentation, feature extraction with or without feature selection techniques, and classification. Erythrocytes segmentation is done using image binarization with marker-controlled watershed segmentation. The six feature sets (morphological feature, texture and intensity feature) have been evaluated using various classifiers such as support vector machine (SVM), k-nearest neighbor (k-NN), and Naive Bayes to choose the better feature set. From the experimental results, it has been observed that the feature set \(\textit{f}_6\) (combination of morphological, texture and intensity feature ranked with ANOVA) outperforms other feature sets. Further, erythrocyte classification has been performed using ANN-GA with \(\textit{f}_6\) feature set. It may also conclude that the various features such as morphological feature, texture and intensity feature are equally important to detect the malaria-infected erythrocyte.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Cuomo, M.J., Noel, L.B., White, D.B.: Diagnosing Medical Parasites: A Public Health Officers Guide to Assisting Laboratory and Medical Officers http://www.phsource.us/PH/PARA/ Diagnosing Medical Parasites (2012)
Di, Ruberto C., Dempster, A., Khan, S., Jarra, B.: Analysis of infected blood cell images using morphological operators. Image Vis. Comput. 20(2), 133–146 (2002)
Nicholas, R.E., Charles, J.P., David, M.R., Adriano, G.D.: Automated image processing method for the diagnosis and classification of malaria on thin blood smears. Med Biol Eng Comput. 44(5), 427–436 (2006)
Tek, F.B., Dempster, A.G., Kale, I.: Parasite detection and identification for automated thin blood film malaria diagnosis. Comput Vis Image Und. 114(1), 21–32 (2010)
Diaz, G., Gonzalez, F.A., Romero, E.: A semi-automatic method for quantification and classification of erythrocytes infected with malaria parasites in microscopic images. J. Biomed. Inform. 42(2), 296–307 (2009)
Springl, V.: Automatic Malaria Diagnosis Through Microscopic Imaging. Faculty of Electrical Engineering, Prague (2009)
Das, D.K., Ghosh, M., Pal, M., Maiti, A.K., Chakraborty, C.: Machine learning approach for automated screening of malaria parasite using light microscopic images. Micron 45, 97–106 (2013)
Devi, S.S., Sheikh, S.A., Laskar, R.H.: Erythrocyte features for malaria parasite detection in microscopic images of thin blood smear: a review. Int. J. Interact. Multimed Artif. Intel. 4(2), 35–39 (2016)
Devi, S.S., Kumar, R., Laskar, R.H.: Recent advances on erythrocyte image segmentation for biomedical applications. In: Fourth International Conference on Soft Computing for Problem Solving (pp. 353–359). Springer, India (2015)
Devi, S.S., Roy, A., Singha, J., Sheikh, S.A., Laskar, R.H.: Malaria infected erythrocyte classification based on a hybrid classifier using microscopic images of thin blood smear. Multimedia Tools Appl. (2016). https://doi.org/10.1007/s11042-016-4264-7
Otsu, N.: A threshold selection method from gray-level histograms. IEEE Trans. Sys. Man and Cyber 9(1), 62–66 (1979)
Devi, S.S., Singha, J., Sharma, M., Laskar, R.H.: Erythrocyte segmentation for quantification in microscopic images of thin blood smears. J. Intell. Fuzzy Syst. 32(4), 2847–2856 (2017)
Burges, C.J.C.: A tutorial on support vector machines for pattern recognition. Data Min. Knowl. Discov. 2, 121–167 (1998)
Weinberger, K.Q., Saul, L.K.: Distance metric learning for large margin nearest neighbor classification. J. Mach. Learn Res. 10, 207–244 (2009)
Russell S, Norvig P (2003) Artificial Intelligence: A Modern Approach, 2nd edn. Prentice Hall. ISBN 978-0137903955
Ahmad, F., Mat-Isa, N.A., Hussain, Z., Boudville, R., Osman, M.K.: Genetic algorithm-artificial neural network (GA-ANN) hybrid intelligence for cancer diagnosis. In: 2nd International Conference on Computational Intelligence, Communication Systems and Networks, pp. 78–83 (2010)
Acknowledgements
The research work has been done in the Speech and Image Processing Laboratory of NIT Silchar, Assam-788010. For malaria parasite identification and database collection, we would like to express our gratitude to Dr. S. A. Sheikh, Silchar Medical College and Hospital, Assam and Dr. A. Talukdar, Head of the Department, Pathology, Cachar Cancer Hospital and Research Centre, Assam.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2020 Springer Nature Singapore Pte Ltd.
About this paper
Cite this paper
Devi, S.S., Herojit Singh, N., Hussain Laskar, R. (2020). Performance Analysis of Various Feature Sets for Malaria-Infected Erythrocyte Detection. In: Das, K., Bansal, J., Deep, K., Nagar, A., Pathipooranam, P., Naidu, R. (eds) Soft Computing for Problem Solving. Advances in Intelligent Systems and Computing, vol 1057. Springer, Singapore. https://doi.org/10.1007/978-981-15-0184-5_24
Download citation
DOI: https://doi.org/10.1007/978-981-15-0184-5_24
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-15-0183-8
Online ISBN: 978-981-15-0184-5
eBook Packages: Intelligent Technologies and RoboticsIntelligent Technologies and Robotics (R0)