Abstract
The studies show that genetic factors are partially involved in spontaneous preterm labor. However, most studies till date have not been successful in establishing a clear causal relationship between spontaneous preterm birth and genetic factors. The progress in recent high-throughput genomic analysis is expected to improve genetic analysis of premature birth. As a result, it has become possible to thoroughly analyze numerous spontaneous preterm labor cases and controls. Additionally, it is possible to target rare genetic variants and de novo mutations that have not been analyzed sufficiently in the past. In the future, detailed analysis will be performed after considering environmental factors such as the microbiome.
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Hata, K. (2020). Genetic Analysis of Spontaneous Preterm Birth. In: Sameshima, H. (eds) Preterm Labor and Delivery. Comprehensive Gynecology and Obstetrics. Springer, Singapore. https://doi.org/10.1007/978-981-13-9875-9_24
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DOI: https://doi.org/10.1007/978-981-13-9875-9_24
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