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Ultrafast Spectroscopy of Hydrogenase Enzyme Models

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Coherent Multidimensional Spectroscopy

Part of the book series: Springer Series in Optical Sciences ((SSOS,volume 226))

Abstract

Hydrogenase enzymes are nature’s solution to using molecular hydrogen as an energy source. While the air-sensitivity of these biological catalysts make them impractical for industrial hydrogen generation, synthetic mimics show promise in acting as effective substitutes. Hydrogenase model compounds also enable detailed investigation of the ultrafast dynamics and chemical reaction mechanisms using ultrafast infrared spectroscopy. This chapter reviews the progress in applying ultrafast transient infrared absorption and multidimensional spectroscopy to a range of small molecule hydrogenase model compounds, as well as several macromolecular and larger constructs. The rich vibrational structure and straightforward chemical modularity of these diiron compounds represent an exciting class of molecules that are, at the same time, excellent model systems for fundamental chemical dynamics, and practical molecular catalytic components with direct application to next-generation hydrogen-based energy strategies.

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Acknowledgements

Our research on hydrogenase models is supported by the National Science Foundation (CHE–1300239 and CHE-1565795).

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Author notes

  1. Peter A. Eckert

    Present address: Oak Ridge National Laboratory, Oak Ridge, TN, USA

Authors and Affiliations

  1. Department of Chemistry, University of Michigan, 930 N. University Ave, Ann Arbor, MI, 48109, USA

    Peter A. Eckert & Kevin J. Kubarych

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  1. Peter A. Eckert
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  2. Kevin J. Kubarych
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Correspondence to Kevin J. Kubarych .

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Editors and Affiliations

  1. Department of Chemistry, Korea University, Seoul, Korea (Republic of)

    Minhaeng Cho

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Eckert, P.A., Kubarych, K.J. (2019). Ultrafast Spectroscopy of Hydrogenase Enzyme Models. In: Cho, M. (eds) Coherent Multidimensional Spectroscopy. Springer Series in Optical Sciences, vol 226. Springer, Singapore. https://doi.org/10.1007/978-981-13-9753-0_11

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