Evolution and Interplay of Water-Associated Human Pathogens
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Cholera serogroups have been identified which later includes O139 serogroup. Genetic assortment of O139 strain changes the epidemiological status of the cholera and developed strategies for the persistence in competition O1 serogroups. Similarly, heterogeneity responsible for virulence of Salmonella has been conventionally attributed to diverse distribution of genetic elements, namely bacteriophages, chromosomal pathogenicity island, transposons, plasmids, etc. Advancement of DNA sequencing and phylogenetic analysis has led to the understanding of the clear evolutionary relationship of various Shigella spp. along with E. coli. The spatial heterogeneity and intrinsic spatial structure of CF lung selection seem to play a vital role in the diversification of P. aeruginosa. Like other commensal bacteria, Helicobacter pylori have evolved several mechanisms to evade immune responses. Wide genome scanning, discovery of the low variation regions, and signature of selective sweeps allowed us to identify the various genes of malaria that underwent mutation throughout the course of evolution. The epidemiological distribution dengue serotypes is similar; however, genetically the serotypes are diverse in nature.
KeywordsSerotypes Genetic assortment Evolution Epidemiology Mutation Antibiotic resistance
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