Abstract
Infectious laryngotracheitis (ILT), caused by Iltovirus or gallid herpesvirus I (GaHV-1) of Alphaherpesvirinae, is an acute highly contagious viral respiratory disease of chickens. The disease is characterized by sneezing, expectoration of blood-mixed mucus, severe haemorrhagic tracheitis and conjunctivitis amidst mortality of up to 70% in its acute form, and a milder form shows varying degrees of catarrhal tracheitis, sinusitis and conjunctivitis with relatively low morbidity and occasional mortality. ILT has been associated with colossal economic loss to the poultry industry due to high mortality, reduced egg production, poor growth and expenses spent on vaccination, biosecurity management and treatment to counteract secondary infections. Vaccination and strict biosecurity measures are the principal components in controlling disease. Live attenuated and recombinant viral vector vaccines are commercially available. The live attenuated tissue culture or chicken embryo origin vaccines significantly reduce the mortality; however, these vaccines retain or regain their virulence after bird-to-bird passage leading to outbreaks simulating classical disease in unprotected flocks. The recombinant viral vector vaccines are reported to be a safer alternative, but still they are not completely safe as they often fail to reduce shedding of the challenge virus posing threat of outbreaks. Now, several new strategies to improve the live attenuated as well as recombinant vector vaccines are being evaluated in order to have a better ILT vaccine that would have least residual virulence and mass application potentials.
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References
Abbas F, Andreasen JR Jr (1996) Comparison of diagnostic tests for infectious laryngotracheitis. Avian Dis 40:290–295
Alcami A, Koszinowski UH (2000) Viral mechanisms of immune evasion. Immunol Today 21:447–455
Alcami A, Symons JA, Khanna A, Smith GL (1998) Poxviruses: capturing cytokines and chemokines. Semin Virol 5:419–427
Anderton TL, Maskell DJ, Preston A (2004) Ciliostasis is a key early event during colonization of canine tracheal tissue by Bordetella bronchiseptica. Microbiology:2843–2855
Andreasen JR Jr, Glisson JR, Villegas P (1990) Differentiation of vaccine strains and Georgia field isolates of infectious laryngotracheitis virus by their restriction endonuclease fragment patterns. Avian Dis 34:646–656
Bagust TJ (1986) Laryngotracheitis (Gallid-1) herpesvirus infection in the chicken. 4. Latency establishment by wild and vaccine strains of ILT virus. Avian Pathol 15:581–595
Bagust TJ, Guy JS (1997) Laryngotracheitis. In: Calnek BW, Barnes HJ, Beard CW, McDougald LR, Saif YM (eds) Diseases of poultry, 10th edn. Iowa State University Press, Ames, pp 527–539
Bagust TJ, Calnek BW, Fahey KJ (1986) Gallid-1 herpesvirus infection in the chicken. 3. Reinvestigation of the pathogenesis of infectious laryngotracheitis in acute and early post-acute respiratory disease. Avian Dis 30:179–190
Basavarajappa MK, Kumar S, Khattar SK, Gebreluul GT, Paldurai A, Samal SK (2014) A recombinant Newcastle disease virus (NDV) expressing infectious laryngotracheitis virus (ILTV) surface glycoprotein D protects against highly virulent ILTV and NDV challenges in chickens. Vaccine 28:3555–3563
Benton WJ, Cover MS, Greene LM (1958) The clinical and serological response of chickens to certain laryngotracheitis viruses. Avian Dis 2:383–396
Boettger CM, Keeler CL (2004) A commercial ILTV CEO vaccine is composed of a mixed population of viruses exhibiting differences in pathogenicity and sequence. In: 10th international symposium on Marek’s Disease and Avian Herpesvirus, East Lansing, Michigan, July 20–23
Bryant NA, Davis-Poynter N, Vanderplasschen A, Alcami A (2003) Glycoprotein G isoforms from some alphaherpesviruses function as broad-spectrum chemokine binding proteins. EMBO J 22(4):833–846
Bubien-Waluszewska A (1981) The cranial nerves. In: King AS, Mclelland J (eds) Form and function in birds, vol 2. London/New York, Academic, pp 385–438
Bublot M, Pritchard N, Swayne DE, Selleck P, Karaca K, Suarez DL (2006) Development and use of fowlpox vectored vaccines for avian influenza. Ann N Y Acad Sci 1081:193–201
Calnek BW, Fahey KJ, Bagust TJ (1986) In vitro infection studies with infectious Laryngotracheitis virus. Avian Dis 30(2):327
Chacón JL, Ferreira AJ (2009) Differentiation of field isolates and vaccine strains of infectious laryngotracheitis virus by DNA sequencing. Vaccine 27:6731–6738
Chacon JL, Mizuma MY, Piantino Ferreira AJ (2010) Characterization by restriction fragment length polymorphism and sequence analysis of field and vaccine strains of infectious laryngotracheitis virus involved in severe outbreaks. Avian Pathol 39(6):425–433
Chang PW, Jasty V, Fry D, Yates VJ (1973) Replication of a cell-culture-modified infectious laryngotracheitis virus in experimentally infected chickens. Avian Dis 17:683–689
Chang PW, Sculco F, Yates VJ (1977) An in vivo and in vitro study of infectious laryngotracheitis virus in chicken leukocytes. Avian Dis 21(4):492–500
Chang PC, Lee YL, Shien JH, Shieh HK (1997) Rapid differentiation of vaccine strains and field isolates of infectious laryngotracheitis virus by restriction fragment length polymorphism of PCR products. J Virol Methods 66:179–186. https://doi.org/10.1016/S0166-0934(97)00050-5
Chen HY, Zhang HY, Li XS, Cui BA, Wang SJ, Geng JW, Li K (2011) Interleukin-18-mediated enhancement of the protective effect of an infectious laryngotracheitis virus glycoprotein B plasmid DNA vaccine in chickens. J Med Microbiol 60:110–116
Coppo MJ, Noormohammadi AH, Hartley CA, Gilkerson JR, Browning GF, Devlin GF (2011) Comparative in vivo safety and efficacy of a glycoprotein G deficient candidate vaccine strain of infectious laryngotracheitis virus delivered via eye drop. Avian Pathol 40:411–417
Coppo MJ, Hartley CA, Devlin JM (2013) Immune responses to infectious laryngotracheitis virus. Dev Comp Immunol 41(3):454–462
Coppo MJC, Devlin JM, Legione AR, Vaz PK, Sang-Won L, Quinteros JA, Gilkerson JR, Ficorilli N, Reading PC, Noormohammadi AH, Hartley CA (2018) Infectious laryngotracheitis virus viral chemokine-binding protein glycoprotein G alters transcription of key inflammatory mediators in vitro and in vivo. J Virol 92(1):e01534–e01517
Craig MI, Rojas MF, van der Ploeg Claudia A, Valeria O, Vagnozzi Ariel E, Perez Andrés M, König Guido A (2017) Molecular characterization and cluster analysis of field isolates of avian infectious laryngotracheitis virus from Argentina. Front Vet Sci 4:212
Crawshaw GJ, Boycott BR (1982) Infectious laryngotracheitis in peafowl and pheasants. Avian Dis 26(397):401
Creelan JL, Calvert VM, Graham DA, McCullough SJ (2006) Rapid detection and characterization from field cases of infectious laryngotracheitis virus by real time polymerase chain reaction and restriction fragment length polymorphism. Avian Pathol 35:173–179
Cruickshank JG, Berry DM, Hay B (1963) The fine structure of infectious laryngotracheitis virus. Virology 20:376–378
Darbyshire JH, Cook JKA, Peters RW (1976) Organ culture studies on the efficiency of infection of chicken tissues with avian infectious bronchitis virus. Br J Exp Pathol 57:443–454
Davison AJ (2010) Herpesvirus systematics. Vet Microbiol 143(1):52–69
Davison AJ, Eberle R, Hayward GS, McGeoch DJ, Minson AC, Pellet PE, Roizman B, Studdert MJ, Thiry E (2005) Family Herpesviridae. In: Fauquet CM, Mayo MA, Maniloff J, Desselberger U, Ball LA (eds) Virus taxonomy. Academic, San Diego, pp 193–212
Davison S, Gingerich EN, Casavant S, Eckroade RJ (2006) Evaluation of the efficacy of a live fowlpox-vectored infectious laryngotracheitis/avian encephalomyelitis vaccine against ILT viral challenge. Avian Dis 50:50–54
Davison AJ, Eberle R, Hayward GS, Mcgeoch DJ, Minson AC, Pellet PE, Roizman B, Studdert MJ, Thiry E (2009) The order herpesvirales. Arch Virol 154:171–177
Devlin JM, Browning GF, Gilkerson JR, Fenton SP, Hartley CA (2008) Comparison of the safety and protective efficacy of vaccination with glycoprotein-G-deficient infectious laryngotracheitis virus delivered via eyedrop, drinking water or aerosol. Avian Pathol 37:83–88
Devlin JM, Viejo-Borbolla A, Browning GF, Noormohammadi AH, Gilkerson JR, Alcami A, Hartley CA (2010) Evaluation of immunological responses to a glycoprotein G deficient candidate vaccine strain of infectious laryngotracheitis virus. Vaccine 28:1325–1332
Devlin JM, Hartley CA, Gilkerson JR, Coppo MJC, Vaz P, Noormohammadi AH, Wells B, Rubite A, Dhand NK, Browning GF (2011) Horizontal transmission dynamics of a glycoprotein G deficient candidate vaccine strain of infectious laryngotracheitis virus and the effect of vaccination on transmission of virulent virus. Vaccine 29:5699–5704
Esaki M, Godoy A, Rosenberger JK, Rosenberger SC, Gardin Y, Yasuda A (2013) Protection and antibody response caused by turkey herpesvirus vector Newcastle disease vaccine. Avian Dis 57:750–755
Fahey KJ, York JJ (1990) The role of mucosal antibody in immunity to infectious laryngotracheitis virus in chickens. J Gen Virol 71:2401–2405
Fahey KJ, Bagust TJ, York JJ (1983) Laryngotracheitis herpesvirus infection in the chicken: the role of humoral antibody in immunity to a graded challenge infection. Avian Pathol 12(4):505–514
Fuchs W, Mettenleiter TC (1996) DNA sequence and transcriptional analysis of the UL1 to UL5 gene cluster of infectious laryngotracheitis virus. J Genet Virol 77:2221–2229
Fuchs W, Veits J, Helferich D, Granzow H, Teifke JP, Mettenleiter TC (2007) Molecular biology of avian infectious laryngotracheitis virus. Vet Res 38:261–279
Fulton RM, Schrader DL, Will M (2000) Effect of route of vaccination on the prevention of infectious laryngotracheitis in commercial egg-laying chickens. Avian Dis 44:8–16
Garcia M (2015) ILT control options present double-edged swords. http://poultryhealthtoday.com/ilt-control-options-are-double-edge-swords
Garcia M (2017) Current and future vaccines and vaccination strategies against infectious laryngotracheitis (ILT) respiratory disease of poultry. Vet Microbiol 206:157–162
GarcÃa M, Volkening V, Riblet SM, Spatz S (2013) Genomic sequence analysis of the United States infectious laryngotracheitis vaccine strains chicken embryo origin (CEO) and tissue culture origin (TCO). Virology 440:64–74
Garcia M, Cheng Y, Spatz SJ, Riblet SM, Schneiders GH, Volkening J (2016) Attenuation and protection efficacy of open reading frame C (ORF C) gene deleted strain of the alphaherpesvirus infectious laryngotracheitis virus (ILTV). J Gen Virol 97:2352–2362
Gelenczei EF, Marty EW (1964) Studies on a tissue-culture-modified infectious laryngotracheitis virus. Avian Dis 8:105–122
Gibbs CS (1934) Infectious laryngotracheitis vaccination mass. Agric Exp Stn Bull 311:1–20
Gimeno IM (2016) Present and future of Marek’s disease and infectious laryngotracheitis virus recombinant viruses. In: 11th international symposium on Marek’s Disease and Avian Herpesvirus, Tours, France, July 6–9
Gimeno IM, Cortes AL, Guy JS, Turpin E, Williams C (2011) Replication of recombinant herpesvirus of turkeys expressing genes of infectious laryngotracheitis virus in specific pathogen free and broiler chickens following in ovo and subcutaneous vaccination. Avian Pathol 40:395–403
Gimeno IM, Cortes AL, Faiz NM, Hernandez-Ortiz BA, Guy JS, Hunt HD, Silva RB (2015) Evaluation of the protection efficacy of a serotype I Marek’s disease virus-vectored bivalent vaccine against infectious laryngotracheitis and Marek’s disease. Avian Dis 59:255–262
Gowthaman V, Singh SD, Dhama K, Barathidasan R, Mathapati BS, Srinivasan P, Saravanan S, Ramakrishnan MA (2014) Molecular detection and characterization of infectious laryngotracheitis virus (Gallid herpesvirus-1) from clinical samples of commercial poultry flocks in India. Virus Dis 25(3):345–349
Granzow H, Klupp BG, Fuchs W, Veits J, Osterrieder N, Mettenleiter TC (2001) Egress of alphaherpesviruses: comparative ultrastructural study. J Virol 75:3675–3684
Griffin AM (1991) The nucleotide sequence of the glycoprotein gB of infectious laryngotracheitis virus: analysis and evolutionary relationship to the homologous gene from other herpesviruses. J Genet Virol 72:393–398
Guo P, Scholz E, Turek J, Nodgreen R, Maloney B (1993) Assembly pathway of avian infectious laryngotracheitis virus. Am J Vet Res 54:2031–2039
Guy JS, Bagust TJ (2003) Laryngotracheitis. In: Saif YM, Barnes HJ, Glisson JR, Fadly AM, McDougald LR, Swayne DE (eds) Diseases of poultry, 11th edn. Iowa State University Press, Ames, pp 121–134
Guy JS, Garcia M (2008) Laryngotracheitis. In: Saif YM, Fadly AM, Glisson JR, McDougald LR, Nolan LK, Swayne DE (eds) Diseases of poultry, 12th edn. Blackwell Publishing Professional, Ames, pp 137–152
Guy JS, Barnes HJ, Morgan LM (1990) Virulence of infectious Laryngotracheitis viruses: comparison of modified-live vaccine viruses and North Carolina field isolates. Avian Dis 34(1):106
Guy JS, Barnes HJ, Smith L (1991) Increased virulence of modified-live infectious laryngotracheitis vaccine virus following bird-to-bird passage. Avian Dis 35:348–355
Guy JS, Barnes HJ, Smith LG (1992) Rapid diagnosis of infectious laryngotracheitis using a monoclonal antibody-based immunoperoxidase procedure. Avian Pathol 21:77–86
Han MG, Kim SJ (2003) Efficacy of live virus vaccines against infectious laryngotracheitis assessed by polymerase chain reaction-restriction fragment length polymorphism. Avian Dis 47:261–271
Hanson LE, Bagust TJ (1991) Infectious laryngotracheitis. In: CALNEK BW (ed) Diseases of poultry, 9th edn. Ames, Iowa State University Press, pp 485–495
Hayles LB, Macdonald KR, Newby WC, Wood CW, Gilchrist EW, MacNeill AC (1976) Epizootiology of infectious laryngotracheitis in British Columbia 1971–1973. Can Vet J 17:101–108
Hidalgo H (2003) Infectious laryngotracheitis: a review. Braz J Poultry Sci 5(3):157–168
Honda T, Taneno A, Sakai E, Yamada S, Takahashi E (1994) Immune response and in vivo distribution of the virus in chickens inoculated with the cell-associated vaccine of attenuated infectious laryngotracheitis (ILT) virus. J Vet Med Sci 56(4):691–695
Hughes CS, Jones RC, Gaskell RM, Jordan FTW, Bradbury JM (1987) Demonstration in live chickens of the carrier state in infectious laryngotracheitis. Res Vet Sci 42(3):407–410
Hughes CS, Gaskell RM, Jones RC, Bradbury JM, Jordan FTW (1989) Effects of certain stress factors on the re-excretion of infectious laryngotracheitis virus from latently infected carrier birds. Res Vet Sci 46:247–276
Hughes CS, Williams RA, Gaskell RM, Jordan FTW, Bradbury JM, Bennett M, Jones RC (1991) Latency and reactivation of infectious laryngotracheitis vaccine virus. Arch Virol 121(1–4):213–218
Islam AFF, Walkden-Brown SW, Groves PJ, Underwood GJ (2008) Kinetics of Marek’s disease virus (MDV) infection in broiler chickens 1: effect of varying vaccination to challenge interval on vaccinal protection and load of MDV and herpesvirus of turkey in the spleen and feather dander over time. Avian Pathol 37:225–235
Johnson MA, Prideaux CT, Kongsuwan K, Sheppard M, Fahey KJ (1991) Gallid herpesvirus 1 (infectious laryngotracheitis virus): cloning and physical maps of the SA-2 strain. Arch Virol 119(3–4):181–198
Johnson MA, Prideaux CT, Kongsuwan K, Tyack SG, Sheppard M (1995a) ICP27 immediate early gene, glycoprotein K (gK) and DNA helicase homologues of infectious laryngotracheitis virus (gallid herpesvirus 1) SA-2 strain. Arch Virol 140:623–634
Johnson MA, Tyack SG, Prideaux CT, Kongsuwan K, Sheppard M (1995b) Sequence characteristics of a gene in infectious laryngotracheitis virus homologous to glycoprotein D of herpes simplex virus. DNA sequence. J DNA Seq Mapp 5:191–194
Johnson YJ, Gedamu N, Colby MM, Myint MS, Steele SE, Salem M, Tablante NL (2005) Wind-borne transmission of infectious laryngotracheitis between commercial poultry operations. Int J Poult Sci 4:263–267
Johnson DI, Vagnozzi AE, Dorea F, Riblet SM, Mundt A, Zavala G, GarcÃa M (2010) Protection against infectious laryngotracheitis by in ovo vaccination with commercially available viral vector recombinant vaccines. Avian Dis 54:1251–1259
Jones RC (2010) Viral respiratory diseases (ILT, aMPV infections, IB): are they ever under control? Br Poult Sci 51(1):1–11
Jones BV, Hennion RM (2008) The preparation of chicken tracheal organ cultures for virus isolation, propagation and titration. Methods Mol Biol 454:103–107
Jordan FTW (1966) A review of the literature on infectious Laryngotracheitis (ILT). Avian Dis 10(1):1
Jordan FTW (1981) Immunity to infectious laryngotracheitis. In: Avian immunology, British Poultry Science symposium series, vol 16. British Poultry Science, Edinburg, pp 245–254
Jordan FT, Evanson HM, Bennett JM (1967) The survival of the virus of infectious laryngotracheitis. Zentralbl Veterinarmed B 14:135–150
Keeler CL, Hazel JW, Hasting JE, Rosenberger JK (1993) Restriction endonuclease analysis of delmarva field isolates of infectious laryngotracheitis virus. Avian Dis 37:418–426
Kernohan G (1931) Infectious laryngotracheitis in pheasants. J Am Vet Med Assoc 78:553–555
Kingsbury FW, Jungherr EL (1958) Indirect transmission of infectious Laryngotracheitis in chickens. Avian Dis 2(1):54
Kingsley DH, Hazel JW, Keeler CL Jr (1994) Identification and characterization of the infectious laryngotracheitis virus glycoprotein C gene. Virology 203:336–343
Kirkpatrick NC, Mahmoudian A, Colson CA, Devlin JM, Noormohammadi AH (2006a) Relationship between mortality: clinical signs and tracheal pathology in infectious laryngotracheitis. Avian Pathol 35:449–453
Kirkpatrick NC, Mahmoudian A, O’Rouke D, Noormohammadia AH (2006b) Differentiation of infectious laryngotracheitis virus isolates by restriction fragment length polymorphic analyses of polymerase chain reaction products amplified from multiple genes. Avian Dis 50:28–34
Kongsuwan K, Prideaux CT, Johnson MA, Sheppard M, Fahey KJ (1991) Nucleotide sequence of the gene encoding infectious laryngotracheitis virus glycoprotein B. Virology 184:404–410
Kongsuwan K, Johnson MA, Prideaux CT, Sheppard M (1993) Identification of an infectious laryngotracheitis virus encoding an immunogenic protein with a predicted Mr of 32 kilodaltons. Virus Res 29:125–140
Kotiw M, Wilks CR, May JT (1982) Differentiation of Infectious laryngotracheitis virus strains using restriction endonucleases. Avian Dis 26(4):718–730
Lee SW, Markham PF, Coppo MJ, Legione AR, Markham JF, Noormohammadi AH, Browning GF, Ficorilli N, Hartley CA, Devlin JM (2012) Attenuated vaccines can recombine to form virulent field viruses. Science 337(6091):188
Leib DA, Bradbury JM, Gaskell RM, Hughes CS, Jones RC (1986) Restriction endonuclease patterns of some European and American isolates of avian infectious laryngotracheitis virus. Avian Dis 30:835–837
Leib DA, Bradbury JM, Hart CA, McCarthy K (1987) Genome isomerism in two alphaherpesviruses:herpesvirus saimiri-1(herpesvirus tamarinus) and avian infectious laryngotracheitis virus. Arch Virol 93(3–4):287–294
Linares JA, Bickford AA, Cooper GL, Charlton BR, Woolcock PR (1994) An outbreak of infectious Laryngotracheitis in California broilers. Avian Dis 38(1):188
Loncoman CA, Hartley CA, Coppo MJC, Vaz PK, Diaz-Méndez A, Browning GF et al (2017) Development and application of a TaqMan single nucleotide polymorphism genotyping assay to study infectious laryngotracheitis virus recombination in the natural host. PLoS One 12(3):e0174590
Mahmoudian A, Markham PF, Noormohammadi AH, Browning GF (2011) Kinetics of transcription of infectious laryngotracheitis virus genes. Comp Immunol Microbiol Infect Dis 35:1–13
May HG, Tittsler RP (1925) Tracheolaryngitis in poultry. J Am Vet Med Assoc 67:229–231
McGeoch DJ, Dalrymple MA, Davison AJ, Dolan A, Frame MC, McNab D, Perry LJ, Scott JE, Taylor P (1988) The complete DNA sequence of the long unique region in the genome of herpes simplex virus type 1. J Genet Virol 69:1531–1574
Menendez KR, GarcÃa M, Spatz S, Tablante NL (2014) Molecular epidemiology of infectious laryngotracheitis: a review. Avian Pathol 43(2):108–117
Mettenleiter TC (2002) Herpesvirus assembly and egress. J Virol 76:1537–1547
Nakamichi K, Matsumoto Y, Otsuka H (2002) Bovine herpesvirus 1 glycoprotein G is necessary for maintaining cell-to-cell junctional adherence among infected cells. Virology 294:22–30
OIE, 1999. HandiSTATUS II. World avian infectious laryngotracheitis animal health status 1999. http://www.oie.int.hs2/sit_mald_cont.asp?c_mald=85&c_cont=6&annee=1999
OIE Terrestrial Manual (2014) Ch. 2.3.3 Avian infectious laryngotracheitis. 1–11
Oldoni I, Garcia M (2007) Characterization of infectious laryngotracheitis virus isolates from the US by polymerase chain reaction and restriction fragment length polymorphism of multiple genome regions. Avian Pathol 36(2):167–176
Oldoni I, RodrÃguez-Avila A, Riblet SM, Zavala G, GarcÃa M (2009) Pathogenicity and growth characteristics of selected infectious laryngotracheitis virus strains from the United States. Avian Pathol 38:47–53
Ou SC, Giambrone JJ (2012) Infectious laryngotracheitis virus in chickens. World J Virol 1:142–149
Parra SHS, Nunez LFN, Ferreira AJP (2016) Epidemiology of Avian infectious laryngotracheitis with special focus to South America: an update. Braz J Poul Sci/RevistaBrasileira de CiênciaAvÃcola 18:551–562
Parra SS, Nunez L, Buim MR, Astolfi-Ferreira CS, Piantino Ferreira AJ (2018) Development of a qPCR for the detection of infectious laryngotracheitis virus (ILTV) based on the gE gene. Br Poult Sci 59(4):402–407. https://doi.org/10.1080/00071668.2018.1479060
Parry CM, Simas JP, Smith VP, Stewart CA, Minson AC, Efstathiou S, Alcami A (2000) A broad spectrum secreted chemokine binding protein encoded by a herpesvirus. J Exp Med 191:573–578
Piccirillo A, Lavezzo E, Niero G, Moreno A, Massi P, Franchin E, Toppo S, Salata C, Palù G (2016) Full genome sequence-based comparative study of wild-type and vaccine strains of infectious laryngotracheitis virus from Italy. PLoS One. https://doi.org/10.1371/journal.pone.0149529
Portz C, Beltrao N, Furian TQ, Junior AB, Macagnan M, Griebeler J, Lima Rosa CA, Colodel EM, Driemeier D, Back A, Barth Schatzmayr OM, Canal CW (2008) Natural infection of turkeys by infectious laryngotracheitis virus. Vet Microbiol 131:57–64
Poulsen DJ, Burton CR, O’Brian JJ, Rabin SJ, Keeler CL Jr (1991) Identification of the infectious laryngotracheitis virus glycoprotein gB gene by the polymerase chain reaction. Virus Genes 5:335–347
Poulsen DJ, Thureen DR, Keeler CL (1998) Comparison of disease susceptibility and resistance in three lines of chickens experimentally infected with infectious laryngotracheitis virus. Poult Sci 77:17–21
Puvarajan B, Sukumar K, Johnson Rajeswar J, Harikrishnan TJ, Balasubramaniam GA (2013) Standardization of molecular based approach in diagnosis of recent outbreaks of infectious laryngotracheitis (ILT) in layers by polymerase chain reaction in Namakkal, Tamilnadu. J Immunol Immunopathol 15(1):55
Reemers SS, Groot Koerkamp MJ, Holstege FC, Van Eden W, Vervelde L (2009) Cellular host transcriptional responses to influenza A virus in chicken tracheal organ cultures differ from responses in in vivo infected trachea. Vet Immunol Immunopathol 132:91–100
Reynolds HA, Watrach AM, Hanson LE (1968) Development of the nuclear inclusion bodies of infectious laryngotracheitis. Avian Dis 12:332–347
Robertson GM, Egerton JR (1981) Replication of infectious laryngotracheitis virus in chickens following vaccination. Aust Vet J 57:119–123
RodrÃguez-Avila A, Oldoni I, Riblet SM, GarcÃa M (2008) Evaluation of the protection elicited by direct and indirect exposure to live attenuated infectious laryngotracheitis virus (ILTV) vaccines against a recent challenge strain from the United States. Avian Pathol 37:287–292
Roizman B, Knipe DM (2001) Herpes simplex viruses and their replication. In: Knipe DM, Howley PM (eds) Fields virology. Lippincott Williams & Wilkins, Philadelphia, pp 2399–2459
Roizman B, Knipe DM, Whiley RJ (2007) Herpes simplex virus. In: Knipe DM, Howley PM (eds) Fields virology. Lippincott Williams & Wilkins, Philadelphia, pp 2501–2601
Roizman B, Pellet PE (2001) The family Herpesviridae: a brief introduction. In: Knipe DM, Howley PM (eds) Fields virology, 4th edn. Lippincott Williams & Wilkins, Philadelphia, pp 2381–2397
Roy P, Fakhrul Islam AFM, Burgess SK, Hunt PW, McNally J, Walkden-Brown SW (2015) Real-time PCR quantification of infectious laryngotracheitis virus in chicken tissues, faeces, isolator-dust and bedding material over 28 days following infection reveals high levels in faeces and dust. J Gen Virol 96:3338–3347
Samberg Y, Cuperstein E, Bendheim U, Aronvici I (1971) The development of a vaccine against avian infectious laryngotracheitis IV. Immunization of chickens with a modified laryngotracheitis vaccine in the drinking water. Avian Dis 15:413–417
Schnitzlein WM, Radzevicius J, Tripathy DN (1994) Propagation of infectious laryngotracheitis virus in an avian liver cell line. Avian Dis 38(2):211–217
Scholz E, Porter RE, Guo P (1994) Differential diagnosis of infectious laryngotracheitis from other avian respiratory diseases by a simplified PCR procedure. J Virol Methods 50:313–322
Sharma SN, Malik BS (1970) Serological evidence of infectious laryngotracheitis, infectious bronchitis and chronic respiratory disease of poultry around Jabalpur (Madhya Pradesh). Indian Vet J 47:466–469
Silva RF, Dunn JR, Cheng HH, Niikura M (2010) A MEQ deleted Marek’s disease virus cloned as a bacterial artificial chromosome is a highly efficacious vaccine. Avian Dis 54:862–869
Singh SB, Singh GR, Singh CM (1964) A preliminary report on the occurrence of infectious laryngotracheitis of poultry in India
Sivaseelan S, Rajan T, Malmarugan S, Balasubramaniam GA, Madheswaran R (2014) Tissue tropism and pathobiology of infectious laryngotracheitis virus in natural cases of chickens. Isr J Vet Med 69(4):197–202
Spatz SJ, Volkening JD, Keeler CL, Kutish GF, Riblet SM, Boettger CM, Clark KF, Zsak L, Afonso CL, Mundt ES, Rock DL, GarcÃa M (2012) Comparative full genome analysis of four infectious laryngotracheitis virus (Gallid herpesvirus-1) virulent isolates from the United States. Virus Genes 44(2):273–285
Srinivasan P, Balachandran C, Gopalakrishna Murthy TR, Saravanan S, Pazhanivel N, Mohan B (2012) Pathology of infectious laryngotracheitis in commercial layer chicken. Indian Vet J 89
Surajit B, Bhumika SF, Nirav R, Mamta P (2016) Sero-prevalence of infectious laryngotracheitis of poultry in India. Indian J Poult Sci 51(2):234–236
Swayne DE, Beck JR, Mickle TR (1997) Efficacy of recombinant fowl Poxvirus vaccine in protecting chickens against a highly pathogenic Mexican-origin H5N2 Avian Influenza Virus. Avian Dis 41:910–922
Thureen DR, Keeler CL Jr (2006) Psittacid herpesvirus 1 and infectious laryngotracheitis virus: comparative genome sequence analysis of two avian alphaherpesviruses. J Virol 80:7863–7872
Tran LC, Kissner JM, Westerman LE, Sears AE (2000) A herpes simplex virus 1 recombinant lacking the glycoprotein G coding sequences is defective in entry through apical surfaces of polarized epithelial cells in culture and in vivo. Proc Natl Acad Sci U S A 97:1818–1822
Tripathy DN, Reed WM (1998) A laboratory manual for the isolation and identification of avian pathogens. In: Swayne DE, Glisson JR, Jackwood MW, Pearson JE, Reed WM (eds) Pox, 4th edn. American Association of Avian Pathologists, New Bolton Center, Kenneth Square, pp 137–140
van Berkel V, Barrett J, Tiffany HL, Fremont DH, Murphy PM, McFadden G, Speck SH, Virgin HWIV (2000) Identification of a gammaherpesvirus selective chemokine binding protein that inhibits chemokine action. J Virol 74:6741–6747
Vagnozzi A, Zavala G, Riblet SM, Mundt A, GarcÃa M (2012) Protection induced by commercially available live-attenuated and recombinant viral vector vaccines against infectious laryngotracheitis virus in broiler chickens. Avian Pathol 41:21–31
Von Bulow V, Klasen A (1983) Effects of avian viruses on cultured chicken bone marrow-derived macrophages. Avian Pathol 12:179–198
Watrach AM, Hanson LE, Watrach MA (1963) The structure of infectious laryngotracheitis virus. Virology 21:601–608
Wild MA, Cook S, Cochran M (1996) A genomic map of infectious laryngotracheitis virus and the sequence and organization of genes present in the unique short and flanking regions. Virus Genes 12:107–116
Williams CJ, Zedek AS (2010) Comparative field evaluations of in ovo applied technology. Poult Sci 89:189–193
Williams RA, Benett M, Bradbury JM, Gaskell RM, Jones RC, Jordan FTW (1992) Demonstration of sites of latency of infectious laryngotracheitis virus using the polymerase chain reaction. J Genet Virol 73:2415–2420
Winterfield RW, So IG (1968) Susceptibility of turkeys to infectious laryngotracheitis. Avian Dis 12:191–202
Yamada S, Matsuo K, Fukuda T, Uchinuno Y (1980) Susceptibility of ducks to the virus of infectious laryngotracheitis. Avian Dis 24:930–938
York JJ, Fahey KJ (1990) Humoral and cell-mediated immune responses to the glycoproteins of infectious laryngotracheitis. Arch Virol 115:289–297
Zavala DL (2008) Epizootiology of infectious laryngotracheitis and presentation of an industry control program. Avian Dis 52:1–7
Zhang S, Jian F, Zhao G, Huang L, Zhang L, Ning C, Wang R, Qi M, Xiao L (2012) Chick embryo tracheal organ: a new and effective in vitro culture model for Cryptosporidium baileyi. Vet Parasitol 188:376–381
Zhao W, Spatz S, Zhang Z, Wen G, Garcia M, Zsak L, Yu Q (2014) Newcastle disease virus (NDV) recombinants expressing infectious Laryngotracheitis virus (ILTV) glycoproteins gB and gD protect chickens against ILTV and NDV challenges. J Virol 88(15):8397–8406
Ziemann K, Mettenleiter TC, Fuchs W (1998) Gene arrangement within the unique long genome region of infectious laryngotracheitis virus is distinct from that of other alphaherpesviruses. J Virol 72:847–852
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Munuswamy, P., Mariappan, A.K., Dhama, K., Reddy, M.R. (2019). Avian Infectious Laryngotracheitis. In: Malik, Y., Singh, R., Yadav, M. (eds) Recent Advances in Animal Virology. Springer, Singapore. https://doi.org/10.1007/978-981-13-9073-9_5
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